PDB: 5KX7 — TKL IRAK4_HUMAN

Total number of chains: 2
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 5KX7B
None None 1 50.0% 5KX7A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL IRAK4 IRAK4_HUMAN 5KX7B Q9NWZ3 163 459 460.0 6YD:9901 Type1 Active DFGin 6.8554 13.2518 BLAminus -138.07, 174.73 58.64, 80.86 -106.82, 34.07 322.11, 87.79 -71.78, -44.9 in-in in 8.6821 Saltbr-in 3.2371 HRD-in -69.76, -47.63 72.83, 1.05 in-in-in SNCiii in-in ActLoopNT-in 2.7592 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -136.02, 154.26 APE9-dihe-na 136.96, -175.89 APE8-dihe-in -105.94, 108.82 APE8-rot-in 305.34 APE67-dihe-in -58.95, -17.61 -32.77, -53.96 APE12-dist-in 9.941 APE11-dist-in 11.4956 APE10-dist-in 6.1747 APE9-dist-in 3.7173 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 2.8 0.213 0.25 B 301.0 289.0 8 30 26 4 [[183, 456]] 1.0 5kx7 TKL_IRAK4_HUMAN TKL 4.1e-84 288.2 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5KX7A Q9NWZ3 192 459 460.0 No_ligand No_ligand Inactive None 7.5134 999.0 None -138.26, 174.6 58.57, 81.01 -106.91, 34.11 322.12, 87.89 -72.06, -44.46 none-none none 999.0 Saltbr-none 999.0 HRD-in -69.47, -47.61 72.64, 1.38 none-in-in SNCnii in-in ActLoopNT-in 2.7601 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -136.3, 154.34 APE9-dihe-na 136.56, -175.85 APE8-dihe-in -106.22, 109.07 APE8-rot-in 305.46 APE67-dihe-in -59.17, -17.42 -32.79, -54.17 APE12-dist-in 9.9579 APE11-dist-in 11.4997 APE10-dist-in 6.1778 APE9-dist-in 3.7121 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 2.8 0.213 0.25 A 301.0 240.0 45 30 26 4 [[183, 456]] 1.0 5kx7 TKL_IRAK4_HUMAN TKL 4.1e-84 288.2 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4

PDB: 5KX7 — TKL IRAK4_HUMAN

Total number of chains: 2
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 5KX7B
None None 1 50.0% 5KX7A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL IRAK4 IRAK4_HUMAN 5KX7B Q9NWZ3 163 459 460.0 6YD:9901 Type1 Active DFGin 6.8554 13.2518 BLAminus -138.07, 174.73 58.64, 80.86 -106.82, 34.07 322.11, 87.79 -71.78, -44.9 in-in in 8.6821 Saltbr-in 3.2371 HRD-in -69.76, -47.63 72.83, 1.05 in-in-in SNCiii in-in ActLoopNT-in 2.7592 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -136.02, 154.26 APE9-dihe-na 136.96, -175.89 APE8-dihe-in -105.94, 108.82 APE8-rot-in 305.34 APE67-dihe-in -58.95, -17.61 -32.77, -53.96 APE12-dist-in 9.941 APE11-dist-in 11.4956 APE10-dist-in 6.1747 APE9-dist-in 3.7173 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 2.8 0.213 0.25 B 301.0 289.0 8 30 26 4 [[183, 456]] 1.0 5kx7 Homo sapiens TKL_IRAK4_HUMAN TKL 4.1e-84 288.2 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 5KX7A Q9NWZ3 192 459 460.0 No_ligand No_ligand Inactive None 7.5134 999.0 None -138.26, 174.6 58.57, 81.01 -106.91, 34.11 322.12, 87.89 -72.06, -44.46 none-none none 999.0 Saltbr-none 999.0 HRD-in -69.47, -47.61 72.64, 1.38 none-in-in SNCnii in-in ActLoopNT-in 2.7601 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -136.3, 154.34 APE9-dihe-na 136.56, -175.85 APE8-dihe-in -106.22, 109.07 APE8-rot-in 305.46 APE67-dihe-in -59.17, -17.42 -32.79, -54.17 APE12-dist-in 9.9579 APE11-dist-in 11.4997 APE10-dist-in 6.1778 APE9-dist-in 3.7121 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 2.8 0.213 0.25 A 301.0 240.0 45 30 26 4 [[183, 456]] 1.0 5kx7 Homo sapiens TKL_IRAK4_HUMAN TKL 4.1e-84 288.2 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4

PDB: 5KX7 — TKL IRAK4_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name