PDB: 5HEZ — TYR JAK2_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 4 100.0% 5HEZB

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR JAK2-2 JAK2_HUMAN 5HEZA 2.66 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oioao APEdist_aaao 1M3, 1M3 Allosteric, Type1 842 - 1132 0 PTR1007,PTR1008 P1057A Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 5HEZB 2.66 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oioao APEdist_aaao 1M3, 1M3 Allosteric, Type1 842 - 1132 0 PTR1007,PTR1008 P1057A Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 5HEZD 2.66 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oioao APEdist_aaao 1M3, 1M3 Allosteric, Type1 842 - 1132 0 PTR1007,PTR1008 P1057A Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 5HEZC 2.66 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oioao APEdist_aaao 1M3, 1M3 Type1, Allosteric 842 - 1132 0 PTR1007,PTR1008 P1057A Tyrosine-protein kinase JAK2

PDB: 5HEZ — TYR JAK2_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 4 100.0% 5HEZB

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR JAK2-2 JAK2_HUMAN 5HEZA 2.66 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oioao APEdist_aaao 1M3, 1M3 Allosteric, Type1 842 - 1132 0 PTR1007,PTR1008 P1057A Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 5HEZB 2.66 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oioao APEdist_aaao 1M3, 1M3 Allosteric, Type1 842 - 1132 0 PTR1007,PTR1008 P1057A Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 5HEZD 2.66 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oioao APEdist_aaao 1M3, 1M3 Allosteric, Type1 842 - 1132 0 PTR1007,PTR1008 P1057A Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 5HEZC 2.66 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oioao APEdist_aaao 1M3, 1M3 Type1, Allosteric 842 - 1132 0 PTR1007,PTR1008 P1057A Tyrosine-protein kinase JAK2 Homo sapiens

PDB: 5HEZ — TYR JAK2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism