PDB: 4ZSE — TYR EGFR_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBtrans 3 75.0% 4ZSEA
DFGin BLBplus 1 25.0% 4ZSED
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 4ZSED P00533 701 1015 1210.0 ANP:4001 ATPlike Inactive DFGin 4.481 13.699 BLBplus -139.61, 164.7 66.53, 26.19 -71.23, 138.48 53.66, 91.47 74.43, 7.23 out-out out 13.877 Saltbr-out 13.686 HRD-in -70.41, -53.51 80.03, -13.83 out-out-none SNCoon out-none ActLoopNT-out 6.522 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 123.0 APE8-dihe-in -83.67, 68.18 APE8-rot-na 28.71 APE67-dihe-in -64.05, -23.47 -60.9, -39.73 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.989 T790M,V948R None None XRAY 1.97 0.191 0.213 D 331 297 14 0 0 12 [[712, 970]] 1.0 4zse TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4ZSEA P00533 699 1007 1210.0 ANP:1101 ATPlike Inactive DFGin 5.335 16.18 BLBtrans -132.89, 171.35 59.18, 30.95 -64.3, 136.47 153.66, 69.99 84.54, -7.18 out-out out 13.41 Saltbr-out 12.542 HRD-in -69.44, -53.13 80.36, -12.32 out-out-none SNCoon out-none ActLoopNT-out 6.5 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 151.84 APE9-dihe-in -73.75, 154.61 APE8-dihe-in -84.04, 78.01 APE8-rot-na 31.44 APE67-dihe-in -73.82, -9.83 -53.67, -42.49 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 14.754 APE9-dist-in 7.631 T790M,V948R None None XRAY 1.97 0.191 0.213 A 331 297 12 0 0 12 [[712, 970]] 1.0 4zse TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4ZSEB P00533 698 1022 1210.0 ANP:2001 ATPlike Inactive DFGin 5.443 16.534 BLBtrans -132.18, 168.84 69.74, 21.23 -63.33, 134.02 158.02, 77.95 88.87, -12.59 out-out out 13.594 Saltbr-out 12.729 HRD-in -70.54, -56.98 84.69, -9.62 out-out-none SNCoon out-none ActLoopNT-out 6.279 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, -169.23 APE9-dihe-in -113.21, 138.46 APE8-dihe-in -83.6, 77.16 APE8-rot-na 29.29 APE67-dihe-in -64.08, -26.4 -59.09, -39.81 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 14.095 APE9-dist-in 7.664 T790M,V948R None None XRAY 1.97 0.191 0.213 B 331 313 12 0 0 12 [[712, 970]] 1.0 4zse TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4ZSEC P00533 700 1013 1210.0 ANP:3001 ATPlike Inactive DFGin 5.527 16.551 BLBtrans -132.06, 169.7 72.1, 15.79 -57.63, 131.91 161.52, 79.23 90.56, -14.81 out-out out 13.464 Saltbr-out 12.84 HRD-in -70.03, -52.52 81.38, -14.98 out-out-none SNCoon out-none ActLoopNT-out 6.218 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 117.83 APE8-dihe-in -83.98, 70.07 APE8-rot-na 31.43 APE67-dihe-in -69.54, -11.42 -60.89, -38.4 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.916 T790M,V948R None None XRAY 1.97 0.191 0.213 C 331 301 13 0 0 13 [[712, 970]] 1.0 4zse TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 4ZSE — TYR EGFR_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBtrans 3 75.0% 4ZSEA
DFGin BLBplus 1 25.0% 4ZSED
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 4ZSED P00533 701 1015 1210.0 ANP:4001 ATPlike Inactive DFGin 4.481 13.699 BLBplus -139.61, 164.7 66.53, 26.19 -71.23, 138.48 53.66, 91.47 74.43, 7.23 out-out out 13.877 Saltbr-out 13.686 HRD-in -70.41, -53.51 80.03, -13.83 out-out-none SNCoon out-none ActLoopNT-out 6.522 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 123.0 APE8-dihe-in -83.67, 68.18 APE8-rot-na 28.71 APE67-dihe-in -64.05, -23.47 -60.9, -39.73 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.989 T790M,V948R None None XRAY 1.97 0.191 0.213 D 331 297 14 0 0 12 [[712, 970]] 1.0 4zse Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4ZSEA P00533 699 1007 1210.0 ANP:1101 ATPlike Inactive DFGin 5.335 16.18 BLBtrans -132.89, 171.35 59.18, 30.95 -64.3, 136.47 153.66, 69.99 84.54, -7.18 out-out out 13.41 Saltbr-out 12.542 HRD-in -69.44, -53.13 80.36, -12.32 out-out-none SNCoon out-none ActLoopNT-out 6.5 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 151.84 APE9-dihe-in -73.75, 154.61 APE8-dihe-in -84.04, 78.01 APE8-rot-na 31.44 APE67-dihe-in -73.82, -9.83 -53.67, -42.49 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 14.754 APE9-dist-in 7.631 T790M,V948R None None XRAY 1.97 0.191 0.213 A 331 297 12 0 0 12 [[712, 970]] 1.0 4zse Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4ZSEB P00533 698 1022 1210.0 ANP:2001 ATPlike Inactive DFGin 5.443 16.534 BLBtrans -132.18, 168.84 69.74, 21.23 -63.33, 134.02 158.02, 77.95 88.87, -12.59 out-out out 13.594 Saltbr-out 12.729 HRD-in -70.54, -56.98 84.69, -9.62 out-out-none SNCoon out-none ActLoopNT-out 6.279 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, -169.23 APE9-dihe-in -113.21, 138.46 APE8-dihe-in -83.6, 77.16 APE8-rot-na 29.29 APE67-dihe-in -64.08, -26.4 -59.09, -39.81 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 14.095 APE9-dist-in 7.664 T790M,V948R None None XRAY 1.97 0.191 0.213 B 331 313 12 0 0 12 [[712, 970]] 1.0 4zse Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4ZSEC P00533 700 1013 1210.0 ANP:3001 ATPlike Inactive DFGin 5.527 16.551 BLBtrans -132.06, 169.7 72.1, 15.79 -57.63, 131.91 161.52, 79.23 90.56, -14.81 out-out out 13.464 Saltbr-out 12.84 HRD-in -70.03, -52.52 81.38, -14.98 out-out-none SNCoon out-none ActLoopNT-out 6.218 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 117.83 APE8-dihe-in -83.98, 70.07 APE8-rot-na 31.43 APE67-dihe-in -69.54, -11.42 -60.89, -38.4 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.916 T790M,V948R None None XRAY 1.97 0.191 0.213 C 331 301 13 0 0 13 [[712, 970]] 1.0 4zse Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 4ZSE — TYR EGFR_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name