PDB: 4ZSE — TYR EGFR_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBtrans 3 75.0% 4ZSEA
DFGin BLBplus 1 25.0% 4ZSED
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 4ZSED P00533 701 1015 1210.0 ANP:4001 ATPlike Inactive DFGin 4.4807 13.6994 BLBplus -139.61, 164.7 66.53, 26.19 -71.23, 138.48 53.66, 91.47 74.43, 7.23 out-out out 13.877 Saltbr-out 13.6856 HRD-in -70.41, -53.51 80.03, -13.83 out-out-none SNCoon out-none ActLoopNT-out 6.5216 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 123.0 APE8-dihe-in -83.67, 68.18 APE8-rot-na 28.71 APE67-dihe-in -64.05, -23.47 -60.9, -39.73 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.9891 T790M,V948R None None XRAY 1.97 0.191 0.213 D 331.0 297.0 14 30 18 12 [[712, 970]] 1.0 4zse TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4ZSEA P00533 699 1007 1210.0 ANP:1101 ATPlike Inactive DFGin 5.3349 16.1805 BLBtrans -132.89, 171.35 59.18, 30.95 -64.3, 136.47 153.66, 69.99 84.54, -7.18 out-out out 13.4098 Saltbr-out 12.5416 HRD-in -69.44, -53.13 80.36, -12.32 out-out-none SNCoon out-none ActLoopNT-out 6.4997 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 151.84 APE9-dihe-in -73.75, 154.61 APE8-dihe-in -84.04, 78.01 APE8-rot-na 31.44 APE67-dihe-in -73.82, -9.83 -53.67, -42.49 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 14.7536 APE9-dist-in 7.6313 T790M,V948R None None XRAY 1.97 0.191 0.213 A 331.0 297.0 12 30 18 12 [[712, 970]] 1.0 4zse TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4ZSEB P00533 698 1022 1210.0 ANP:2001 ATPlike Inactive DFGin 5.4426 16.5343 BLBtrans -132.18, 168.84 69.74, 21.23 -63.33, 134.02 158.02, 77.95 88.87, -12.59 out-out out 13.5937 Saltbr-out 12.7288 HRD-in -70.54, -56.98 84.69, -9.62 out-out-none SNCoon out-none ActLoopNT-out 6.279 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, -169.23 APE9-dihe-in -113.21, 138.46 APE8-dihe-in -83.6, 77.16 APE8-rot-na 29.29 APE67-dihe-in -64.08, -26.4 -59.09, -39.81 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 14.0951 APE9-dist-in 7.6641 T790M,V948R None None XRAY 1.97 0.191 0.213 B 331.0 313.0 12 30 18 12 [[712, 970]] 1.0 4zse TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4ZSEC P00533 700 1013 1210.0 ANP:3001 ATPlike Inactive DFGin 5.5274 16.5509 BLBtrans -132.06, 169.7 72.1, 15.79 -57.63, 131.91 161.52, 79.23 90.56, -14.81 out-out out 13.4639 Saltbr-out 12.8398 HRD-in -70.03, -52.52 81.38, -14.98 out-out-none SNCoon out-none ActLoopNT-out 6.2175 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 117.83 APE8-dihe-in -83.98, 70.07 APE8-rot-na 31.43 APE67-dihe-in -69.54, -11.42 -60.89, -38.4 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.9162 T790M,V948R None None XRAY 1.97 0.191 0.213 C 331.0 301.0 13 30 17 13 [[712, 970]] 1.0 4zse TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 4ZSE — TYR EGFR_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBtrans 3 75.0% 4ZSEA
DFGin BLBplus 1 25.0% 4ZSED
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 4ZSED P00533 701 1015 1210.0 ANP:4001 ATPlike Inactive DFGin 4.4807 13.6994 BLBplus -139.61, 164.7 66.53, 26.19 -71.23, 138.48 53.66, 91.47 74.43, 7.23 out-out out 13.877 Saltbr-out 13.6856 HRD-in -70.41, -53.51 80.03, -13.83 out-out-none SNCoon out-none ActLoopNT-out 6.5216 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 123.0 APE8-dihe-in -83.67, 68.18 APE8-rot-na 28.71 APE67-dihe-in -64.05, -23.47 -60.9, -39.73 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.9891 T790M,V948R None None XRAY 1.97 0.191 0.213 D 331.0 297.0 14 30 18 12 [[712, 970]] 1.0 4zse Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4ZSEA P00533 699 1007 1210.0 ANP:1101 ATPlike Inactive DFGin 5.3349 16.1805 BLBtrans -132.89, 171.35 59.18, 30.95 -64.3, 136.47 153.66, 69.99 84.54, -7.18 out-out out 13.4098 Saltbr-out 12.5416 HRD-in -69.44, -53.13 80.36, -12.32 out-out-none SNCoon out-none ActLoopNT-out 6.4997 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 151.84 APE9-dihe-in -73.75, 154.61 APE8-dihe-in -84.04, 78.01 APE8-rot-na 31.44 APE67-dihe-in -73.82, -9.83 -53.67, -42.49 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 14.7536 APE9-dist-in 7.6313 T790M,V948R None None XRAY 1.97 0.191 0.213 A 331.0 297.0 12 30 18 12 [[712, 970]] 1.0 4zse Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4ZSEB P00533 698 1022 1210.0 ANP:2001 ATPlike Inactive DFGin 5.4426 16.5343 BLBtrans -132.18, 168.84 69.74, 21.23 -63.33, 134.02 158.02, 77.95 88.87, -12.59 out-out out 13.5937 Saltbr-out 12.7288 HRD-in -70.54, -56.98 84.69, -9.62 out-out-none SNCoon out-none ActLoopNT-out 6.279 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, -169.23 APE9-dihe-in -113.21, 138.46 APE8-dihe-in -83.6, 77.16 APE8-rot-na 29.29 APE67-dihe-in -64.08, -26.4 -59.09, -39.81 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 14.0951 APE9-dist-in 7.6641 T790M,V948R None None XRAY 1.97 0.191 0.213 B 331.0 313.0 12 30 18 12 [[712, 970]] 1.0 4zse Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4ZSEC P00533 700 1013 1210.0 ANP:3001 ATPlike Inactive DFGin 5.5274 16.5509 BLBtrans -132.06, 169.7 72.1, 15.79 -57.63, 131.91 161.52, 79.23 90.56, -14.81 out-out out 13.4639 Saltbr-out 12.8398 HRD-in -70.03, -52.52 81.38, -14.98 out-out-none SNCoon out-none ActLoopNT-out 6.2175 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 117.83 APE8-dihe-in -83.98, 70.07 APE8-rot-na 31.43 APE67-dihe-in -69.54, -11.42 -60.89, -38.4 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.9162 T790M,V948R None None XRAY 1.97 0.191 0.213 C 331.0 301.0 13 30 17 13 [[712, 970]] 1.0 4zse Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 4ZSE — TYR EGFR_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name