PDB: 4RMZ — TKL IRAK4_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 4RMZA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL IRAK4 IRAK4_HUMAN 4RMZA Q9NWZ3 165 458 460.0 T20:501 Type1 Inactive DFGin 6.9177 13.9891 BLAminus -126.68, 170.9 71.61, 84.5 -108.32, 13.5 307.27, 99.22 -63.08, -23.58 in-out in 9.2564 Saltbr-out 5.0284 HRD-in -71.37, -54.68 82.53, 0.08 out-in-in SNCoii in-in ActLoopNT-in 2.6851 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -142.07, 154.46 APE9-dihe-na 140.89, -175.55 APE8-dihe-in -107.53, 124.9 APE8-rot-in 311.29 APE67-dihe-in -64.19, -16.01 -66.65, -36.99 APE12-dist-in 10.1681 APE11-dist-in 11.8109 APE10-dist-in 6.8502 APE9-dist-in 3.935 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 2.2 0.239 0.296 A 307.0 287.0 7 30 27 3 [[183, 456]] 1.0 4rmz TKL_IRAK4_HUMAN TKL 4.4e-84 288.1 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 4RMZB Q9NWZ3 165 458 460.0 T20:501 Type1 Inactive DFGin 6.6818 13.8372 BLAminus -127.34, 178.11 67.71, 81.3 -107.41, 14.46 311.78, 87.68 -59.65, -35.76 in-out in 9.1851 Saltbr-out 4.3576 HRD-in -77.65, -51.27 81.38, -11.53 out-in-in SNCoii in-in ActLoopNT-in 2.8032 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -127.02, 148.94 APE9-dihe-na 142.43, 179.5 APE8-dihe-in -98.65, 120.34 APE8-rot-in 323.49 APE67-dihe-in -67.37, -15.66 -55.22, -41.75 APE12-dist-in 10.2326 APE11-dist-in 12.0489 APE10-dist-in 6.7697 APE9-dist-in 4.476 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 2.2 0.239 0.296 B 307.0 284.0 10 30 24 6 [[183, 456]] 1.0 4rmz TKL_IRAK4_HUMAN TKL 4.4e-84 288.1 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4

PDB: 4RMZ — TKL IRAK4_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 4RMZA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL IRAK4 IRAK4_HUMAN 4RMZA Q9NWZ3 165 458 460.0 T20:501 Type1 Inactive DFGin 6.9177 13.9891 BLAminus -126.68, 170.9 71.61, 84.5 -108.32, 13.5 307.27, 99.22 -63.08, -23.58 in-out in 9.2564 Saltbr-out 5.0284 HRD-in -71.37, -54.68 82.53, 0.08 out-in-in SNCoii in-in ActLoopNT-in 2.6851 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -142.07, 154.46 APE9-dihe-na 140.89, -175.55 APE8-dihe-in -107.53, 124.9 APE8-rot-in 311.29 APE67-dihe-in -64.19, -16.01 -66.65, -36.99 APE12-dist-in 10.1681 APE11-dist-in 11.8109 APE10-dist-in 6.8502 APE9-dist-in 3.935 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 2.2 0.239 0.296 A 307.0 287.0 7 30 27 3 [[183, 456]] 1.0 4rmz Homo sapiens TKL_IRAK4_HUMAN TKL 4.4e-84 288.1 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 4RMZB Q9NWZ3 165 458 460.0 T20:501 Type1 Inactive DFGin 6.6818 13.8372 BLAminus -127.34, 178.11 67.71, 81.3 -107.41, 14.46 311.78, 87.68 -59.65, -35.76 in-out in 9.1851 Saltbr-out 4.3576 HRD-in -77.65, -51.27 81.38, -11.53 out-in-in SNCoii in-in ActLoopNT-in 2.8032 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -127.02, 148.94 APE9-dihe-na 142.43, 179.5 APE8-dihe-in -98.65, 120.34 APE8-rot-in 323.49 APE67-dihe-in -67.37, -15.66 -55.22, -41.75 APE12-dist-in 10.2326 APE11-dist-in 12.0489 APE10-dist-in 6.7697 APE9-dist-in 4.476 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 2.2 0.239 0.296 B 307.0 284.0 10 30 24 6 [[183, 456]] 1.0 4rmz Homo sapiens TKL_IRAK4_HUMAN TKL 4.4e-84 288.1 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4

PDB: 4RMZ — TKL IRAK4_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name