PDB: 4RIY — 2 kinases

Total number of chains: 4
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 50.0% 4RIYC
DFGin None 2 50.0% 4RIYD
All chains - renumbered by
Uniprot PDB Alignment

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 4RIYB P00533 688 984 1210.0 ADP:61001 ATPlike Inactive DFGin 5.952 14.655 None -154.99, 131.23 -173.19, -76.87 64.96, 12.46 300.69, 132.23 -71.94, -28.32 in-in in 8.685 Saltbr-in 2.95 HRD-out -79.99, 96.69 -77.78, 9.7 in-in-none SNCiin in-none ActLoopNT-in 2.884 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 133.59 APE8-dihe-in -76.15, 93.2 APE8-rot-na 346.43 APE67-dihe-in -79.33, 6.83 -64.49, -46.47 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.35 V948R,F997A,L1001A None None XRAY 2.981 0.221 0.267 B 345 293 4 0 0 4 [[712, 970]] 1.0 4riy TYR_EGFR_HUMAN TYR 9.4e-88 299.9 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4RIYD P00533 688 984 1210.0 ADP:61001 ATPlike Inactive DFGin 5.892 14.398 None -146.72, -160.68 90.34, -82.61 63.94, 14.36 297.22, 112.71 -69.53, -27.12 in-in in 8.333 Saltbr-in 2.327 HRD-in -73.91, -45.57 61.02, 4.8 in-in-in SNCiii in-in ActLoopNT-in 2.976 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -106.34, 113.28 APE9-dihe-in -130.38, 137.58 APE8-dihe-in -69.37, 99.85 APE8-rot-na 344.82 APE67-dihe-in -75.56, 6.57 -58.1, -42.52 APE12-dist-na 11.232 APE11-dist-na 10.201 APE10-dist-na 9.961 APE9-dist-in 6.258 V948R,F997A,L1001A None None XRAY 2.981 0.221 0.267 D 345 297 0 0 0 0 [[712, 970]] 1.0 4riy TYR_EGFR_HUMAN TYR 9.4e-88 299.9 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR ERBB3 ERBB3_HUMAN 4RIYA P21860 699 979 1342.0 ANP:61101 ATPlike Pseudo DFGin 5.753 12.868 BLBplus -123.9, 168.71 62.98, 31.45 -82.39, 142.59 52.35, 86.17 78.8, -6.78 out-na out 15.044 Saltbr-na 999.0 HRD-in -75.26, -54.75 69.16, 2.85 na-out-none SNCaon out-none ActLoopNT-out 6.45 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, -9.22 APE8-rot-na 31.12 APE67-dihe-in -85.56, -1.17 -67.69, -25.89 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 E928G None None XRAY 2.981 0.221 0.267 A 326 269 12 0 0 12 [[709, 967]] 1.0 4riy TYR_ERBB3_HUMAN TYR 1.3e-79 273.1 2 260 259 851 852 853 855 857 742 759 763 831 833 832 834 893 881 876 875 874 873 872 871 870 788 Receptor tyrosine-protein kinase erbB-3
TYR ERBB3 ERBB3_HUMAN 4RIYC P21860 699 979 1342.0 ANP:61101 ATPlike Pseudo DFGin 5.577 13.185 BLBplus -124.39, 168.66 63.11, 31.61 -82.48, 141.95 52.91, 86.81 78.36, -7.08 out-na out 15.605 Saltbr-na 999.0 HRD-in -74.67, -54.96 68.56, 2.02 na-out-out SNCaoo out-out ActLoopNT-out 6.525 ActLoopCT-out TYR APEdihe_oioai APEdist_aaao APE10-dihe-out -99.97, 8.97 APE9-dihe-in -62.65, 132.93 APE8-dihe-out -66.25, -9.79 APE8-rot-na 341.07 APE67-dihe-in -85.25, -1.58 -67.21, -25.34 APE12-dist-na 22.285 APE11-dist-na 20.535 APE10-dist-na 15.613 APE9-dist-out 10.163 E928G None None XRAY 2.981 0.221 0.267 C 326 275 6 0 0 0 [[709, 967]] 1.0 4riy TYR_ERBB3_HUMAN TYR 1.3e-79 273.1 2 260 259 851 852 853 855 857 742 759 763 831 833 832 834 893 881 876 875 874 873 872 871 870 788 Receptor tyrosine-protein kinase erbB-3

PDB: 4RIY — 2 kinases

Total number of chains: 4
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 50.0% 4RIYC
DFGin None 2 50.0% 4RIYD
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 4RIYB P00533 688 984 1210.0 ADP:61001 ATPlike Inactive DFGin 5.952 14.655 None -154.99, 131.23 -173.19, -76.87 64.96, 12.46 300.69, 132.23 -71.94, -28.32 in-in in 8.685 Saltbr-in 2.95 HRD-out -79.99, 96.69 -77.78, 9.7 in-in-none SNCiin in-none ActLoopNT-in 2.884 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 133.59 APE8-dihe-in -76.15, 93.2 APE8-rot-na 346.43 APE67-dihe-in -79.33, 6.83 -64.49, -46.47 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.35 V948R,F997A,L1001A None None XRAY 2.981 0.221 0.267 B 345 293 4 0 0 4 [[712, 970]] 1.0 4riy Homo sapiens TYR_EGFR_HUMAN TYR 9.4e-88 299.9 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4RIYD P00533 688 984 1210.0 ADP:61001 ATPlike Inactive DFGin 5.892 14.398 None -146.72, -160.68 90.34, -82.61 63.94, 14.36 297.22, 112.71 -69.53, -27.12 in-in in 8.333 Saltbr-in 2.327 HRD-in -73.91, -45.57 61.02, 4.8 in-in-in SNCiii in-in ActLoopNT-in 2.976 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -106.34, 113.28 APE9-dihe-in -130.38, 137.58 APE8-dihe-in -69.37, 99.85 APE8-rot-na 344.82 APE67-dihe-in -75.56, 6.57 -58.1, -42.52 APE12-dist-na 11.232 APE11-dist-na 10.201 APE10-dist-na 9.961 APE9-dist-in 6.258 V948R,F997A,L1001A None None XRAY 2.981 0.221 0.267 D 345 297 0 0 0 0 [[712, 970]] 1.0 4riy Homo sapiens TYR_EGFR_HUMAN TYR 9.4e-88 299.9 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR ERBB3 ERBB3_HUMAN 4RIYA P21860 699 979 1342.0 ANP:61101 ATPlike Pseudo DFGin 5.753 12.868 BLBplus -123.9, 168.71 62.98, 31.45 -82.39, 142.59 52.35, 86.17 78.8, -6.78 out-na out 15.044 Saltbr-na 999.0 HRD-in -75.26, -54.75 69.16, 2.85 na-out-none SNCaon out-none ActLoopNT-out 6.45 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, -9.22 APE8-rot-na 31.12 APE67-dihe-in -85.56, -1.17 -67.69, -25.89 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 E928G None None XRAY 2.981 0.221 0.267 A 326 269 12 0 0 12 [[709, 967]] 1.0 4riy Homo sapiens TYR_ERBB3_HUMAN TYR 1.3e-79 273.1 2 260 259 851 852 853 855 857 742 759 763 831 833 832 834 893 881 876 875 874 873 872 871 870 788 Receptor tyrosine-protein kinase erbB-3
TYR ERBB3 ERBB3_HUMAN 4RIYC P21860 699 979 1342.0 ANP:61101 ATPlike Pseudo DFGin 5.577 13.185 BLBplus -124.39, 168.66 63.11, 31.61 -82.48, 141.95 52.91, 86.81 78.36, -7.08 out-na out 15.605 Saltbr-na 999.0 HRD-in -74.67, -54.96 68.56, 2.02 na-out-out SNCaoo out-out ActLoopNT-out 6.525 ActLoopCT-out TYR APEdihe_oioai APEdist_aaao APE10-dihe-out -99.97, 8.97 APE9-dihe-in -62.65, 132.93 APE8-dihe-out -66.25, -9.79 APE8-rot-na 341.07 APE67-dihe-in -85.25, -1.58 -67.21, -25.34 APE12-dist-na 22.285 APE11-dist-na 20.535 APE10-dist-na 15.613 APE9-dist-out 10.163 E928G None None XRAY 2.981 0.221 0.267 C 326 275 6 0 0 0 [[709, 967]] 1.0 4riy Homo sapiens TYR_ERBB3_HUMAN TYR 1.3e-79 273.1 2 260 259 851 852 853 855 857 742 759 763 831 833 832 834 893 881 876 875 874 873 872 871 870 788 Receptor tyrosine-protein kinase erbB-3

PDB: 4RIY — 2 kinases

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name