PDB: 4RIY — 2 kinases

Total number of chains: 4
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 50.0% 4RIYC
DFGin None 2 50.0% 4RIYD
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 4RIYB P00533 688 984 1210.0 ADP:61001 ATPlike Inactive DFGin 5.9519 14.6551 None -154.99, 131.23 -173.19, -76.87 64.96, 12.46 300.69, 132.23 -71.94, -28.32 in-in in 8.6852 Saltbr-in 2.9501 HRD-out -79.99, 96.69 -77.78, 9.7 in-in-none SNCiin in-none ActLoopNT-in 2.8837 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 133.59 APE8-dihe-in -76.15, 93.2 APE8-rot-na 346.43 APE67-dihe-in -79.33, 6.83 -64.49, -46.47 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.3497 V948R,F997A,L1001A None None XRAY 2.981 0.221 0.267 B 345.0 293.0 4 30 26 4 [[712, 970]] 1.0 4riy TYR_EGFR_HUMAN TYR 9.4e-88 299.9 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4RIYD P00533 688 984 1210.0 ADP:61001 ATPlike Inactive DFGin 5.8922 14.3982 None -146.72, -160.68 90.34, -82.61 63.94, 14.36 297.22, 112.71 -69.53, -27.12 in-in in 8.3332 Saltbr-in 2.3271 HRD-in -73.91, -45.57 61.02, 4.8 in-in-in SNCiii in-in ActLoopNT-in 2.9763 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -106.34, 113.28 APE9-dihe-in -130.38, 137.58 APE8-dihe-in -69.37, 99.85 APE8-rot-na 344.82 APE67-dihe-in -75.56, 6.57 -58.1, -42.52 APE12-dist-na 11.2323 APE11-dist-na 10.2008 APE10-dist-na 9.9606 APE9-dist-in 6.2575 V948R,F997A,L1001A None None XRAY 2.981 0.221 0.267 D 345.0 297.0 0 30 30 0 [[712, 970]] 1.0 4riy TYR_EGFR_HUMAN TYR 9.4e-88 299.9 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR ERBB3 ERBB3_HUMAN 4RIYA P21860 699 979 1342.0 ANP:61101 ATPlike Pseudo DFGin 5.753 12.8685 BLBplus -123.9, 168.71 62.98, 31.45 -82.39, 142.59 52.35, 86.17 78.8, -6.78 out-na out 15.0438 Saltbr-na 999.0 HRD-in -75.26, -54.75 69.16, 2.85 na-out-none SNCaon out-none ActLoopNT-out 6.4496 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, -9.22 APE8-rot-na 31.12 APE67-dihe-in -85.56, -1.17 -67.69, -25.89 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 E928G None None XRAY 2.981 0.221 0.267 A 326.0 269.0 12 30 18 12 [[709, 967]] 1.0 4riy TYR_ERBB3_HUMAN TYR 1.3e-79 273.1 2.0 260.0 259.0 851 852 853 855 857 742 759 763 831 833 832 834.0 893 881 876 875 874 873 872 871 870 788 Receptor tyrosine-protein kinase erbB-3
TYR ERBB3 ERBB3_HUMAN 4RIYC P21860 699 979 1342.0 ANP:61101 ATPlike Pseudo DFGin 5.5774 13.185 BLBplus -124.39, 168.66 63.11, 31.61 -82.48, 141.95 52.91, 86.81 78.36, -7.08 out-na out 15.6054 Saltbr-na 999.0 HRD-in -74.67, -54.96 68.56, 2.02 na-out-out SNCaoo out-out ActLoopNT-out 6.5253 ActLoopCT-out TYR APEdihe_oioai APEdist_aaao APE10-dihe-out -99.97, 8.97 APE9-dihe-in -62.65, 132.93 APE8-dihe-out -66.25, -9.79 APE8-rot-na 341.07 APE67-dihe-in -85.25, -1.58 -67.21, -25.34 APE12-dist-na 22.2853 APE11-dist-na 20.5354 APE10-dist-na 15.6134 APE9-dist-out 10.1634 E928G None None XRAY 2.981 0.221 0.267 C 326.0 275.0 6 30 30 0 [[709, 967]] 1.0 4riy TYR_ERBB3_HUMAN TYR 1.3e-79 273.1 2.0 260.0 259.0 851 852 853 855 857 742 759 763 831 833 832 834.0 893 881 876 875 874 873 872 871 870 788 Receptor tyrosine-protein kinase erbB-3

PDB: 4RIY — 2 kinases

Total number of chains: 4
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 50.0% 4RIYC
DFGin None 2 50.0% 4RIYD
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 4RIYB P00533 688 984 1210.0 ADP:61001 ATPlike Inactive DFGin 5.9519 14.6551 None -154.99, 131.23 -173.19, -76.87 64.96, 12.46 300.69, 132.23 -71.94, -28.32 in-in in 8.6852 Saltbr-in 2.9501 HRD-out -79.99, 96.69 -77.78, 9.7 in-in-none SNCiin in-none ActLoopNT-in 2.8837 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 133.59 APE8-dihe-in -76.15, 93.2 APE8-rot-na 346.43 APE67-dihe-in -79.33, 6.83 -64.49, -46.47 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.3497 V948R,F997A,L1001A None None XRAY 2.981 0.221 0.267 B 345.0 293.0 4 30 26 4 [[712, 970]] 1.0 4riy Homo sapiens TYR_EGFR_HUMAN TYR 9.4e-88 299.9 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4RIYD P00533 688 984 1210.0 ADP:61001 ATPlike Inactive DFGin 5.8922 14.3982 None -146.72, -160.68 90.34, -82.61 63.94, 14.36 297.22, 112.71 -69.53, -27.12 in-in in 8.3332 Saltbr-in 2.3271 HRD-in -73.91, -45.57 61.02, 4.8 in-in-in SNCiii in-in ActLoopNT-in 2.9763 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -106.34, 113.28 APE9-dihe-in -130.38, 137.58 APE8-dihe-in -69.37, 99.85 APE8-rot-na 344.82 APE67-dihe-in -75.56, 6.57 -58.1, -42.52 APE12-dist-na 11.2323 APE11-dist-na 10.2008 APE10-dist-na 9.9606 APE9-dist-in 6.2575 V948R,F997A,L1001A None None XRAY 2.981 0.221 0.267 D 345.0 297.0 0 30 30 0 [[712, 970]] 1.0 4riy Homo sapiens TYR_EGFR_HUMAN TYR 9.4e-88 299.9 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR ERBB3 ERBB3_HUMAN 4RIYA P21860 699 979 1342.0 ANP:61101 ATPlike Pseudo DFGin 5.753 12.8685 BLBplus -123.9, 168.71 62.98, 31.45 -82.39, 142.59 52.35, 86.17 78.8, -6.78 out-na out 15.0438 Saltbr-na 999.0 HRD-in -75.26, -54.75 69.16, 2.85 na-out-none SNCaon out-none ActLoopNT-out 6.4496 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, -9.22 APE8-rot-na 31.12 APE67-dihe-in -85.56, -1.17 -67.69, -25.89 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 E928G None None XRAY 2.981 0.221 0.267 A 326.0 269.0 12 30 18 12 [[709, 967]] 1.0 4riy Homo sapiens TYR_ERBB3_HUMAN TYR 1.3e-79 273.1 2.0 260.0 259.0 851 852 853 855 857 742 759 763 831 833 832 834.0 893 881 876 875 874 873 872 871 870 788 Receptor tyrosine-protein kinase erbB-3
TYR ERBB3 ERBB3_HUMAN 4RIYC P21860 699 979 1342.0 ANP:61101 ATPlike Pseudo DFGin 5.5774 13.185 BLBplus -124.39, 168.66 63.11, 31.61 -82.48, 141.95 52.91, 86.81 78.36, -7.08 out-na out 15.6054 Saltbr-na 999.0 HRD-in -74.67, -54.96 68.56, 2.02 na-out-out SNCaoo out-out ActLoopNT-out 6.5253 ActLoopCT-out TYR APEdihe_oioai APEdist_aaao APE10-dihe-out -99.97, 8.97 APE9-dihe-in -62.65, 132.93 APE8-dihe-out -66.25, -9.79 APE8-rot-na 341.07 APE67-dihe-in -85.25, -1.58 -67.21, -25.34 APE12-dist-na 22.2853 APE11-dist-na 20.5354 APE10-dist-na 15.6134 APE9-dist-out 10.1634 E928G None None XRAY 2.981 0.221 0.267 C 326.0 275.0 6 30 30 0 [[709, 967]] 1.0 4riy Homo sapiens TYR_ERBB3_HUMAN TYR 1.3e-79 273.1 2.0 260.0 259.0 851 852 853 855 857 742 759 763 831 833 832 834.0 893 881 876 875 874 873 872 871 870 788 Receptor tyrosine-protein kinase erbB-3

PDB: 4RIY — 2 kinases

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name