PDB: 4RIX — 2 kinases

Total number of chains: 4
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 50.0% 4RIXC
DFGin None 2 50.0% 4RIXD
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 4RIXB P00533 688 984 1210.0 ADP:61001 ATPlike Inactive DFGin 5.9187 14.5792 None -139.87, -153.46 71.8, -106.42 74.55, 12.91 300.13, 117.16 -73.01, -18.89 in-in in 8.7784 Saltbr-in 2.8507 HRD-out -79.93, 91.22 -73.37, 9.67 in-in-none SNCiin in-none ActLoopNT-in 2.815 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 134.04 APE8-dihe-in -57.54, 105.82 APE8-rot-na 336.15 APE67-dihe-in -83.65, 5.55 -71.82, -34.06 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 6.6445 V948R,F997A,L1001A None None XRAY 3.1 0.21 0.258 B 345.0 293.0 4 30 26 4 [[712, 970]] 1.0 4rix TYR_EGFR_HUMAN TYR 9.4e-88 299.9 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4RIXD P00533 688 984 1210.0 ADP:61001 ATPlike Inactive DFGin 5.9838 14.3961 None -138.76, -155.76 70.86, -102.17 73.98, 14.44 299.1, 114.44 -71.0, -18.03 in-in in 8.4327 Saltbr-in 2.1297 HRD-in -75.74, -46.31 59.89, 5.04 in-in-in SNCiii in-in ActLoopNT-in 2.8788 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -117.43, 115.77 APE9-dihe-in -128.43, 136.25 APE8-dihe-in -57.6, 106.59 APE8-rot-na 335.5 APE67-dihe-in -81.04, 4.3 -70.58, -32.32 APE12-dist-na 11.3356 APE11-dist-na 10.1436 APE10-dist-na 10.4275 APE9-dist-in 5.9873 V948R,F997A,L1001A None None XRAY 3.1 0.21 0.258 D 345.0 297.0 0 30 30 0 [[712, 970]] 1.0 4rix TYR_EGFR_HUMAN TYR 9.4e-88 299.9 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR ERBB3 ERBB3_HUMAN 4RIXA P21860 699 979 1342.0 ANP:61101 ATPlike Pseudo DFGin 5.5341 12.788 BLBplus -125.2, 170.11 60.89, 28.84 -82.14, 140.77 56.51, 90.87 77.72, -6.25 out-na out 15.0398 Saltbr-na 999.0 HRD-in -77.1, -53.12 66.52, 0.72 na-out-none SNCaon out-none ActLoopNT-out 6.5125 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, -5.5 APE8-rot-na 30.9 APE67-dihe-in -82.84, -10.3 -67.07, -25.63 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 Q809R None None XRAY 3.1 0.21 0.258 A 326.0 269.0 12 30 18 12 [[709, 967]] 1.0 4rix TYR_ERBB3_HUMAN TYR 9.7e-80 273.5 2.0 260.0 259.0 851 852 853 855 857 742 759 763 831 833 832 834.0 893 881 876 875 874 873 872 871 870 788 Receptor tyrosine-protein kinase erbB-3
TYR ERBB3 ERBB3_HUMAN 4RIXC P21860 699 979 1342.0 ANP:61101 ATPlike Pseudo DFGin 5.5566 13.1159 BLBplus -126.64, 170.72 61.2, 28.92 -82.69, 140.73 56.76, 91.32 77.44, -6.2 out-na out 15.4732 Saltbr-na 999.0 HRD-in -76.48, -52.61 66.58, -0.13 na-out-out SNCaoo out-out ActLoopNT-out 6.3725 ActLoopCT-out TYR APEdihe_oioai APEdist_aaao APE10-dihe-out -112.15, 5.58 APE9-dihe-in -58.87, 135.06 APE8-dihe-out -71.85, -6.39 APE8-rot-na 348.17 APE67-dihe-in -82.4, -10.58 -67.81, -25.66 APE12-dist-na 21.6583 APE11-dist-na 20.6117 APE10-dist-na 15.6054 APE9-dist-out 9.9687 Q809R None None XRAY 3.1 0.21 0.258 C 326.0 275.0 6 30 30 0 [[709, 967]] 1.0 4rix TYR_ERBB3_HUMAN TYR 9.7e-80 273.5 2.0 260.0 259.0 851 852 853 855 857 742 759 763 831 833 832 834.0 893 881 876 875 874 873 872 871 870 788 Receptor tyrosine-protein kinase erbB-3

PDB: 4RIX — 2 kinases

Total number of chains: 4
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 50.0% 4RIXC
DFGin None 2 50.0% 4RIXD
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 4RIXB P00533 688 984 1210.0 ADP:61001 ATPlike Inactive DFGin 5.9187 14.5792 None -139.87, -153.46 71.8, -106.42 74.55, 12.91 300.13, 117.16 -73.01, -18.89 in-in in 8.7784 Saltbr-in 2.8507 HRD-out -79.93, 91.22 -73.37, 9.67 in-in-none SNCiin in-none ActLoopNT-in 2.815 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 134.04 APE8-dihe-in -57.54, 105.82 APE8-rot-na 336.15 APE67-dihe-in -83.65, 5.55 -71.82, -34.06 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 6.6445 V948R,F997A,L1001A None None XRAY 3.1 0.21 0.258 B 345.0 293.0 4 30 26 4 [[712, 970]] 1.0 4rix Homo sapiens TYR_EGFR_HUMAN TYR 9.4e-88 299.9 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4RIXD P00533 688 984 1210.0 ADP:61001 ATPlike Inactive DFGin 5.9838 14.3961 None -138.76, -155.76 70.86, -102.17 73.98, 14.44 299.1, 114.44 -71.0, -18.03 in-in in 8.4327 Saltbr-in 2.1297 HRD-in -75.74, -46.31 59.89, 5.04 in-in-in SNCiii in-in ActLoopNT-in 2.8788 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -117.43, 115.77 APE9-dihe-in -128.43, 136.25 APE8-dihe-in -57.6, 106.59 APE8-rot-na 335.5 APE67-dihe-in -81.04, 4.3 -70.58, -32.32 APE12-dist-na 11.3356 APE11-dist-na 10.1436 APE10-dist-na 10.4275 APE9-dist-in 5.9873 V948R,F997A,L1001A None None XRAY 3.1 0.21 0.258 D 345.0 297.0 0 30 30 0 [[712, 970]] 1.0 4rix Homo sapiens TYR_EGFR_HUMAN TYR 9.4e-88 299.9 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR ERBB3 ERBB3_HUMAN 4RIXA P21860 699 979 1342.0 ANP:61101 ATPlike Pseudo DFGin 5.5341 12.788 BLBplus -125.2, 170.11 60.89, 28.84 -82.14, 140.77 56.51, 90.87 77.72, -6.25 out-na out 15.0398 Saltbr-na 999.0 HRD-in -77.1, -53.12 66.52, 0.72 na-out-none SNCaon out-none ActLoopNT-out 6.5125 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, -5.5 APE8-rot-na 30.9 APE67-dihe-in -82.84, -10.3 -67.07, -25.63 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 Q809R None None XRAY 3.1 0.21 0.258 A 326.0 269.0 12 30 18 12 [[709, 967]] 1.0 4rix Homo sapiens TYR_ERBB3_HUMAN TYR 9.7e-80 273.5 2.0 260.0 259.0 851 852 853 855 857 742 759 763 831 833 832 834.0 893 881 876 875 874 873 872 871 870 788 Receptor tyrosine-protein kinase erbB-3
TYR ERBB3 ERBB3_HUMAN 4RIXC P21860 699 979 1342.0 ANP:61101 ATPlike Pseudo DFGin 5.5566 13.1159 BLBplus -126.64, 170.72 61.2, 28.92 -82.69, 140.73 56.76, 91.32 77.44, -6.2 out-na out 15.4732 Saltbr-na 999.0 HRD-in -76.48, -52.61 66.58, -0.13 na-out-out SNCaoo out-out ActLoopNT-out 6.3725 ActLoopCT-out TYR APEdihe_oioai APEdist_aaao APE10-dihe-out -112.15, 5.58 APE9-dihe-in -58.87, 135.06 APE8-dihe-out -71.85, -6.39 APE8-rot-na 348.17 APE67-dihe-in -82.4, -10.58 -67.81, -25.66 APE12-dist-na 21.6583 APE11-dist-na 20.6117 APE10-dist-na 15.6054 APE9-dist-out 9.9687 Q809R None None XRAY 3.1 0.21 0.258 C 326.0 275.0 6 30 30 0 [[709, 967]] 1.0 4rix Homo sapiens TYR_ERBB3_HUMAN TYR 9.7e-80 273.5 2.0 260.0 259.0 851 852 853 855 857 742 759 763 831 833 832 834.0 893 881 876 875 874 873 872 871 870 788 Receptor tyrosine-protein kinase erbB-3

PDB: 4RIX — 2 kinases

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name