PDB: 4LG4 — STE STK3_HUMAN

Total number of chains: 6
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBminus 4 66.7% 4LG4A
DFGin None 1 16.7% 4LG4F
None None 1 16.7% 4LG4D
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE STK3 STK3_HUMAN 4LG4A Q13188 18 308 491.0 No_ligand No_ligand Inactive DFGin 6.432 16.709 BLBminus -149.12, 171.46 46.69, 61.4 -60.75, 152.52 291.15, 39.97 -79.18, 173.35 out-out out 10.108 Saltbr-out 4.074 HRD-in -76.71, -50.91 85.64, -28.8 out-out-out SNCooo out-out ActLoopNT-out 9.203 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioo APE10-dihe-na -62.56, -37.12 APE9-dihe-na -57.6, -19.4 APE8-dihe-in -131.0, 81.65 APE8-rot-in 305.42 APE67-dihe-in -65.11, -24.08 -99.22, 5.56 APE12-dist-in 11.633 APE11-dist-in 9.26 APE10-dist-out 14.084 APE9-dist-out 12.417 D146N None None XRAY 2.42 0.194 0.231 A 299 289 2 0 0 0 [[27, 278]] 1.0 4lg4 STE_STK3_HUMAN STE 1.9e-100 341.5 2 257 256 163 164 165 167 169 56 70 74 143 145 144 146 203 191 186 185 184 183 182 181 180 100 Serine/threonine-protein kinase 3
STE STK3 STK3_HUMAN 4LG4B Q13188 18 308 491.0 No_ligand No_ligand Inactive DFGin 5.314 14.731 BLBminus -140.21, 165.65 51.04, 86.72 -80.54, 176.1 305.81, 78.15 -53.27, 999.0 out-out out 10.695 Saltbr-out 5.399 HRD-in -69.34, -48.39 74.3, -6.21 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_nnno APE10-dihe-na -68.75, -29.95 APE9-dihe-na -83.67, -6.62 APE8-dihe-out -47.16, -50.18 APE8-rot-in 302.82 APE67-dihe-in -50.74, -37.0 -61.88, -26.78 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 11.24 D146N None None XRAY 2.42 0.194 0.231 B 299 284 7 0 0 4 [[27, 278]] 1.0 4lg4 STE_STK3_HUMAN STE 1.9e-100 341.5 2 257 256 163 164 165 167 169 56 70 74 143 145 144 146 203 191 186 185 184 183 182 181 180 100 Serine/threonine-protein kinase 3
STE STK3 STK3_HUMAN 4LG4C Q13188 18 307 491.0 No_ligand No_ligand Inactive DFGin 6.226 16.418 BLBminus -145.61, 169.46 51.28, 57.2 -59.23, 151.18 287.92, 51.76 -86.76, 150.02 in-in in 9.911 Saltbr-in 3.44 HRD-in -75.35, -49.3 83.39, -19.28 in-out-out SNCioo out-out ActLoopNT-out 9.193 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -63.35, -30.69 APE9-dihe-na -66.56, -23.25 APE8-dihe-in -134.1, 75.91 APE8-rot-out 66.24 APE67-dihe-in -62.05, -27.19 -90.36, 7.85 APE12-dist-in 11.691 APE11-dist-in 9.722 APE10-dist-out 14.664 APE9-dist-out 12.281 D146N None None XRAY 2.42 0.194 0.231 C 299 288 2 0 0 0 [[27, 278]] 1.0 4lg4 STE_STK3_HUMAN STE 1.9e-100 341.5 2 257 256 163 164 165 167 169 56 70 74 143 145 144 146 203 191 186 185 184 183 182 181 180 100 Serine/threonine-protein kinase 3
STE STK3 STK3_HUMAN 4LG4E Q13188 18 308 491.0 No_ligand No_ligand Inactive DFGin 6.263 16.204 BLBminus -130.31, 173.17 47.8, 59.45 -58.92, 151.45 279.66, 80.29 -84.51, 152.04 out-out out 10.135 Saltbr-out 4.21 HRD-in -72.01, -47.83 74.71, -8.47 out-out-out SNCooo out-out ActLoopNT-out 8.91 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioo APE10-dihe-na -71.15, -28.45 APE9-dihe-na -67.18, -21.74 APE8-dihe-in -127.36, 70.14 APE8-rot-in 309.85 APE67-dihe-in -69.41, -34.62 -90.13, 14.25 APE12-dist-in 11.192 APE11-dist-in 9.221 APE10-dist-out 14.066 APE9-dist-out 12.293 D146N None None XRAY 2.42 0.194 0.231 E 299 275 16 0 0 6 [[27, 278]] 1.0 4lg4 STE_STK3_HUMAN STE 1.9e-100 341.5 2 257 256 163 164 165 167 169 56 70 74 143 145 144 146 203 191 186 185 184 183 182 181 180 100 Serine/threonine-protein kinase 3
STE STK3 STK3_HUMAN 4LG4F Q13188 18 310 491.0 No_ligand No_ligand Inactive DFGin 4.8 15.191 None -138.38, 162.54 47.11, 83.6 -66.57, 999.0 302.94, 84.23 999.0, 999.0 out-out out 10.79 Saltbr-out 6.42 HRD-in -72.45, -47.39 76.74, -5.57 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -102.3 APE8-dihe-in -134.65, 156.4 APE8-rot-out 45.22 APE67-dihe-in -63.77, -27.55 -98.01, 1.25 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 10.121 D146N None None XRAY 2.42 0.194 0.231 F 299 276 17 0 0 17 [[27, 278]] 1.0 4lg4 STE_STK3_HUMAN STE 1.9e-100 341.5 2 257 256 163 164 165 167 169 56 70 74 143 145 144 146 203 191 186 185 184 183 182 181 180 100 Serine/threonine-protein kinase 3
STE STK3 STK3_HUMAN 4LG4D Q13188 26 308 491.0 No_ligand No_ligand Inactive None 999.0 999.0 None -138.74, -179.79 -96.29, 999.0 999.0, 999.0 999.0, 999.0 999.0, 999.0 out-out out 10.335 Saltbr-out 5.21 HRD-in -73.23, -47.35 79.5, -18.38 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -41.57 APE8-dihe-in -147.49, 145.83 APE8-rot-out 185.09 APE67-dihe-in -63.59, -23.02 -102.14, -5.83 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 10.516 D146N None None XRAY 2.42 0.194 0.231 D 299 250 33 0 0 18 [[27, 278]] 1.0 4lg4 STE_STK3_HUMAN STE 1.9e-100 341.5 2 257 256 163 164 165 167 169 56 70 74 143 145 144 146 203 191 186 185 184 183 182 181 180 100 Serine/threonine-protein kinase 3

PDB: 4LG4 — STE STK3_HUMAN

Total number of chains: 6
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBminus 4 66.7% 4LG4A
DFGin None 1 16.7% 4LG4F
None None 1 16.7% 4LG4D
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE STK3 STK3_HUMAN 4LG4A Q13188 18 308 491.0 No_ligand No_ligand Inactive DFGin 6.432 16.709 BLBminus -149.12, 171.46 46.69, 61.4 -60.75, 152.52 291.15, 39.97 -79.18, 173.35 out-out out 10.108 Saltbr-out 4.074 HRD-in -76.71, -50.91 85.64, -28.8 out-out-out SNCooo out-out ActLoopNT-out 9.203 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioo APE10-dihe-na -62.56, -37.12 APE9-dihe-na -57.6, -19.4 APE8-dihe-in -131.0, 81.65 APE8-rot-in 305.42 APE67-dihe-in -65.11, -24.08 -99.22, 5.56 APE12-dist-in 11.633 APE11-dist-in 9.26 APE10-dist-out 14.084 APE9-dist-out 12.417 D146N None None XRAY 2.42 0.194 0.231 A 299 289 2 0 0 0 [[27, 278]] 1.0 4lg4 Homo sapiens STE_STK3_HUMAN STE 1.9e-100 341.5 2 257 256 163 164 165 167 169 56 70 74 143 145 144 146 203 191 186 185 184 183 182 181 180 100 Serine/threonine-protein kinase 3
STE STK3 STK3_HUMAN 4LG4B Q13188 18 308 491.0 No_ligand No_ligand Inactive DFGin 5.314 14.731 BLBminus -140.21, 165.65 51.04, 86.72 -80.54, 176.1 305.81, 78.15 -53.27, 999.0 out-out out 10.695 Saltbr-out 5.399 HRD-in -69.34, -48.39 74.3, -6.21 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_nnno APE10-dihe-na -68.75, -29.95 APE9-dihe-na -83.67, -6.62 APE8-dihe-out -47.16, -50.18 APE8-rot-in 302.82 APE67-dihe-in -50.74, -37.0 -61.88, -26.78 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 11.24 D146N None None XRAY 2.42 0.194 0.231 B 299 284 7 0 0 4 [[27, 278]] 1.0 4lg4 Homo sapiens STE_STK3_HUMAN STE 1.9e-100 341.5 2 257 256 163 164 165 167 169 56 70 74 143 145 144 146 203 191 186 185 184 183 182 181 180 100 Serine/threonine-protein kinase 3
STE STK3 STK3_HUMAN 4LG4C Q13188 18 307 491.0 No_ligand No_ligand Inactive DFGin 6.226 16.418 BLBminus -145.61, 169.46 51.28, 57.2 -59.23, 151.18 287.92, 51.76 -86.76, 150.02 in-in in 9.911 Saltbr-in 3.44 HRD-in -75.35, -49.3 83.39, -19.28 in-out-out SNCioo out-out ActLoopNT-out 9.193 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -63.35, -30.69 APE9-dihe-na -66.56, -23.25 APE8-dihe-in -134.1, 75.91 APE8-rot-out 66.24 APE67-dihe-in -62.05, -27.19 -90.36, 7.85 APE12-dist-in 11.691 APE11-dist-in 9.722 APE10-dist-out 14.664 APE9-dist-out 12.281 D146N None None XRAY 2.42 0.194 0.231 C 299 288 2 0 0 0 [[27, 278]] 1.0 4lg4 Homo sapiens STE_STK3_HUMAN STE 1.9e-100 341.5 2 257 256 163 164 165 167 169 56 70 74 143 145 144 146 203 191 186 185 184 183 182 181 180 100 Serine/threonine-protein kinase 3
STE STK3 STK3_HUMAN 4LG4E Q13188 18 308 491.0 No_ligand No_ligand Inactive DFGin 6.263 16.204 BLBminus -130.31, 173.17 47.8, 59.45 -58.92, 151.45 279.66, 80.29 -84.51, 152.04 out-out out 10.135 Saltbr-out 4.21 HRD-in -72.01, -47.83 74.71, -8.47 out-out-out SNCooo out-out ActLoopNT-out 8.91 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioo APE10-dihe-na -71.15, -28.45 APE9-dihe-na -67.18, -21.74 APE8-dihe-in -127.36, 70.14 APE8-rot-in 309.85 APE67-dihe-in -69.41, -34.62 -90.13, 14.25 APE12-dist-in 11.192 APE11-dist-in 9.221 APE10-dist-out 14.066 APE9-dist-out 12.293 D146N None None XRAY 2.42 0.194 0.231 E 299 275 16 0 0 6 [[27, 278]] 1.0 4lg4 Homo sapiens STE_STK3_HUMAN STE 1.9e-100 341.5 2 257 256 163 164 165 167 169 56 70 74 143 145 144 146 203 191 186 185 184 183 182 181 180 100 Serine/threonine-protein kinase 3
STE STK3 STK3_HUMAN 4LG4F Q13188 18 310 491.0 No_ligand No_ligand Inactive DFGin 4.8 15.191 None -138.38, 162.54 47.11, 83.6 -66.57, 999.0 302.94, 84.23 999.0, 999.0 out-out out 10.79 Saltbr-out 6.42 HRD-in -72.45, -47.39 76.74, -5.57 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -102.3 APE8-dihe-in -134.65, 156.4 APE8-rot-out 45.22 APE67-dihe-in -63.77, -27.55 -98.01, 1.25 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 10.121 D146N None None XRAY 2.42 0.194 0.231 F 299 276 17 0 0 17 [[27, 278]] 1.0 4lg4 Homo sapiens STE_STK3_HUMAN STE 1.9e-100 341.5 2 257 256 163 164 165 167 169 56 70 74 143 145 144 146 203 191 186 185 184 183 182 181 180 100 Serine/threonine-protein kinase 3
STE STK3 STK3_HUMAN 4LG4D Q13188 26 308 491.0 No_ligand No_ligand Inactive None 999.0 999.0 None -138.74, -179.79 -96.29, 999.0 999.0, 999.0 999.0, 999.0 999.0, 999.0 out-out out 10.335 Saltbr-out 5.21 HRD-in -73.23, -47.35 79.5, -18.38 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -41.57 APE8-dihe-in -147.49, 145.83 APE8-rot-out 185.09 APE67-dihe-in -63.59, -23.02 -102.14, -5.83 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 10.516 D146N None None XRAY 2.42 0.194 0.231 D 299 250 33 0 0 18 [[27, 278]] 1.0 4lg4 Homo sapiens STE_STK3_HUMAN STE 1.9e-100 341.5 2 257 256 163 164 165 167 169 56 70 74 143 145 144 146 203 191 186 185 184 183 182 181 180 100 Serine/threonine-protein kinase 3

PDB: 4LG4 — STE STK3_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name