PDB: 4I21 — TYR EGFR_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout None 2 100.0% 4I21A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 4I21A P00533 703 1019 1210.0 No_ligand No_ligand Inactive DFGout 14.7497 4.5517 None -100.28, 172.71 -126.15, 170.08 -163.08, 33.14 210.49, 157.35 95.37, -18.48 out-out out 12.846 Saltbr-out 9.6468 HRD-in -39.7, -18.75 35.21, 19.68 out-in-in SNCoii in-in ActLoopNT-in 2.8657 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -97.28, 128.62 APE9-dihe-in -128.58, 144.56 APE8-dihe-in -73.89, 96.03 APE8-rot-na 28.14 APE67-dihe-in -80.61, -14.84 -75.13, -32.8 APE12-dist-na 12.1295 APE11-dist-na 11.7682 APE10-dist-na 11.2474 APE9-dist-in 7.1732 T790M,L858R None None XRAY 3.37 0.233 0.279 A 329.0 290.0 0 30 30 0 [[712, 970]] 1.0 4i21 TYR_EGFR_HUMAN TYR 8.6e-87 296.8 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4I21B P00533 703 1020 1210.0 No_ligand No_ligand Inactive DFGout 14.7541 4.5497 None -99.82, 173.29 -125.81, 171.27 -163.87, 32.69 210.88, 156.94 95.05, -18.24 out-out out 12.8425 Saltbr-out 9.6196 HRD-in -39.87, -18.86 36.39, 17.8 out-in-in SNCoii in-in ActLoopNT-in 2.8247 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -97.87, 127.85 APE9-dihe-in -127.9, 144.31 APE8-dihe-in -73.55, 96.22 APE8-rot-na 28.09 APE67-dihe-in -81.62, -14.13 -75.34, -32.76 APE12-dist-na 12.1347 APE11-dist-na 11.7692 APE10-dist-na 11.2473 APE9-dist-in 7.1724 T790M,L858R None None XRAY 3.37 0.233 0.279 B 329.0 302.0 0 30 30 0 [[712, 970]] 1.0 4i21 TYR_EGFR_HUMAN TYR 8.6e-87 296.8 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 4I21 — TYR EGFR_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout None 2 100.0% 4I21A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 4I21A P00533 703 1019 1210.0 No_ligand No_ligand Inactive DFGout 14.7497 4.5517 None -100.28, 172.71 -126.15, 170.08 -163.08, 33.14 210.49, 157.35 95.37, -18.48 out-out out 12.846 Saltbr-out 9.6468 HRD-in -39.7, -18.75 35.21, 19.68 out-in-in SNCoii in-in ActLoopNT-in 2.8657 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -97.28, 128.62 APE9-dihe-in -128.58, 144.56 APE8-dihe-in -73.89, 96.03 APE8-rot-na 28.14 APE67-dihe-in -80.61, -14.84 -75.13, -32.8 APE12-dist-na 12.1295 APE11-dist-na 11.7682 APE10-dist-na 11.2474 APE9-dist-in 7.1732 T790M,L858R None None XRAY 3.37 0.233 0.279 A 329.0 290.0 0 30 30 0 [[712, 970]] 1.0 4i21 Homo sapiens TYR_EGFR_HUMAN TYR 8.6e-87 296.8 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4I21B P00533 703 1020 1210.0 No_ligand No_ligand Inactive DFGout 14.7541 4.5497 None -99.82, 173.29 -125.81, 171.27 -163.87, 32.69 210.88, 156.94 95.05, -18.24 out-out out 12.8425 Saltbr-out 9.6196 HRD-in -39.87, -18.86 36.39, 17.8 out-in-in SNCoii in-in ActLoopNT-in 2.8247 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -97.87, 127.85 APE9-dihe-in -127.9, 144.31 APE8-dihe-in -73.55, 96.22 APE8-rot-na 28.09 APE67-dihe-in -81.62, -14.13 -75.34, -32.76 APE12-dist-na 12.1347 APE11-dist-na 11.7692 APE10-dist-na 11.2473 APE9-dist-in 7.1724 T790M,L858R None None XRAY 3.37 0.233 0.279 B 329.0 302.0 0 30 30 0 [[712, 970]] 1.0 4i21 Homo sapiens TYR_EGFR_HUMAN TYR 8.6e-87 296.8 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 4I21 — TYR EGFR_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name