PDB: 4I21 — TYR EGFR_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout None 2 100.0% 4I21A
All chains - renumbered by
Uniprot PDB Alignment

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 4I21A P00533 703 1019 1210.0 No_ligand No_ligand Inactive DFGout 14.75 4.552 None -100.28, 172.71 -126.15, 170.08 -163.08, 33.14 210.49, 157.35 95.37, -18.48 out-out out 12.846 Saltbr-out 9.647 HRD-in -39.7, -18.75 35.21, 19.68 out-in-in SNCoii in-in ActLoopNT-in 2.866 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -97.28, 128.62 APE9-dihe-in -128.58, 144.56 APE8-dihe-in -73.89, 96.03 APE8-rot-na 28.14 APE67-dihe-in -80.61, -14.84 -75.13, -32.8 APE12-dist-na 12.13 APE11-dist-na 11.768 APE10-dist-na 11.247 APE9-dist-in 7.173 T790M,L858R None None XRAY 3.37 0.233 0.279 A 329 290 0 0 0 0 [[712, 970]] 1.0 4i21 TYR_EGFR_HUMAN TYR 8.6e-87 296.8 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4I21B P00533 703 1020 1210.0 No_ligand No_ligand Inactive DFGout 14.754 4.55 None -99.82, 173.29 -125.81, 171.27 -163.87, 32.69 210.88, 156.94 95.05, -18.24 out-out out 12.842 Saltbr-out 9.62 HRD-in -39.87, -18.86 36.39, 17.8 out-in-in SNCoii in-in ActLoopNT-in 2.825 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -97.87, 127.85 APE9-dihe-in -127.9, 144.31 APE8-dihe-in -73.55, 96.22 APE8-rot-na 28.09 APE67-dihe-in -81.62, -14.13 -75.34, -32.76 APE12-dist-na 12.135 APE11-dist-na 11.769 APE10-dist-na 11.247 APE9-dist-in 7.172 T790M,L858R None None XRAY 3.37 0.233 0.279 B 329 302 0 0 0 0 [[712, 970]] 1.0 4i21 TYR_EGFR_HUMAN TYR 8.6e-87 296.8 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 4I21 — TYR EGFR_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout None 2 100.0% 4I21A
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 4I21A P00533 703 1019 1210.0 No_ligand No_ligand Inactive DFGout 14.75 4.552 None -100.28, 172.71 -126.15, 170.08 -163.08, 33.14 210.49, 157.35 95.37, -18.48 out-out out 12.846 Saltbr-out 9.647 HRD-in -39.7, -18.75 35.21, 19.68 out-in-in SNCoii in-in ActLoopNT-in 2.866 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -97.28, 128.62 APE9-dihe-in -128.58, 144.56 APE8-dihe-in -73.89, 96.03 APE8-rot-na 28.14 APE67-dihe-in -80.61, -14.84 -75.13, -32.8 APE12-dist-na 12.13 APE11-dist-na 11.768 APE10-dist-na 11.247 APE9-dist-in 7.173 T790M,L858R None None XRAY 3.37 0.233 0.279 A 329 290 0 0 0 0 [[712, 970]] 1.0 4i21 Homo sapiens TYR_EGFR_HUMAN TYR 8.6e-87 296.8 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4I21B P00533 703 1020 1210.0 No_ligand No_ligand Inactive DFGout 14.754 4.55 None -99.82, 173.29 -125.81, 171.27 -163.87, 32.69 210.88, 156.94 95.05, -18.24 out-out out 12.842 Saltbr-out 9.62 HRD-in -39.87, -18.86 36.39, 17.8 out-in-in SNCoii in-in ActLoopNT-in 2.825 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -97.87, 127.85 APE9-dihe-in -127.9, 144.31 APE8-dihe-in -73.55, 96.22 APE8-rot-na 28.09 APE67-dihe-in -81.62, -14.13 -75.34, -32.76 APE12-dist-na 12.135 APE11-dist-na 11.769 APE10-dist-na 11.247 APE9-dist-in 7.172 T790M,L858R None None XRAY 3.37 0.233 0.279 B 329 302 0 0 0 0 [[712, 970]] 1.0 4i21 Homo sapiens TYR_EGFR_HUMAN TYR 8.6e-87 296.8 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 4I21 — TYR EGFR_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name