PDB: 4EHZ — TYR JAK1_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 4 100.0% 4EHZA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK1-2 JAK1_HUMAN 4EHZA P23458 858 1154 1154.0 JAK:1201 Type1 Inactive DFGin 6.2945 13.63 ABAminus -122.46, 12.74 -158.91, 149.59 -139.33, 23.83 295.89, 89.08 -61.4, -20.25 in-in in 7.7955 Saltbr-in 2.9362 HRD-in -79.41, -51.26 80.05, -0.3 in-in-out SNCiio in-out ActLoopNT-in 2.8662 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -94.49, 24.25 APE9-dihe-in -61.79, 133.39 APE8-dihe-in -76.86, 73.91 APE8-rot-na 30.52 APE67-dihe-in -75.94, -6.94 -60.76, -27.83 APE12-dist-na 11.4383 APE11-dist-na 13.1596 APE10-dist-na 9.8707 APE9-dist-in 7.0319 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 2.174 0.174 0.229 A 302.0 292.0 5 31 31 0 [[583, 847], [875, 1151]] 2.0 4ehz TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4EHZB P23458 865 1154 1154.0 JAK:1201 Type1 Inactive DFGin 6.3175 13.7298 ABAminus -116.35, 3.51 -150.61, 148.16 -138.87, 32.34 292.95, 86.02 -67.41, -23.21 in-in in 7.8685 Saltbr-in 2.7634 HRD-in -83.57, -44.01 70.15, -1.08 in-in-out SNCiio in-out ActLoopNT-in 2.7334 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -104.9, 29.19 APE9-dihe-in -67.89, 136.88 APE8-dihe-in -75.68, 68.81 APE8-rot-na 33.04 APE67-dihe-in -71.9, -6.58 -49.99, -36.99 APE12-dist-na 11.4195 APE11-dist-na 13.393 APE10-dist-na 10.1247 APE9-dist-in 6.9909 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 2.174 0.174 0.229 B 302.0 282.0 8 31 31 0 [[583, 847], [875, 1151]] 2.0 4ehz TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4EHZC P23458 866 1154 1154.0 JAK:1201 Type1 Inactive DFGin 6.3172 13.6208 ABAminus -118.15, 8.14 -148.22, 154.09 -141.74, 25.14 292.74, 84.54 -60.05, -18.24 in-in in 7.8585 Saltbr-in 2.8403 HRD-in -77.85, -48.09 78.3, 3.1 in-in-out SNCiio in-out ActLoopNT-in 2.7238 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -117.81, 30.11 APE9-dihe-in -57.01, 145.43 APE8-dihe-in -85.32, 74.95 APE8-rot-na 31.15 APE67-dihe-in -74.27, -3.28 -56.74, -31.49 APE12-dist-na 10.9751 APE11-dist-na 13.0044 APE10-dist-na 10.1803 APE9-dist-in 6.676 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 2.174 0.174 0.229 C 302.0 280.0 9 31 31 0 [[583, 847], [875, 1151]] 2.0 4ehz TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4EHZD P23458 865 1154 1154.0 JAK:1201 Type1 Inactive DFGin 6.4285 13.533 ABAminus -123.86, 16.47 -158.34, 146.22 -137.38, 32.15 296.06, 77.8 -67.83, -20.15 in-in in 7.6786 Saltbr-in 2.9996 HRD-in -85.88, -43.73 70.18, 7.9 in-in-out SNCiio in-out ActLoopNT-in 2.8 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -108.38, 26.48 APE9-dihe-in -59.77, 138.32 APE8-dihe-in -81.72, 74.58 APE8-rot-na 32.67 APE67-dihe-in -77.67, -4.82 -52.47, -31.56 APE12-dist-na 11.0435 APE11-dist-na 12.9621 APE10-dist-na 10.0088 APE9-dist-in 6.6881 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 2.174 0.174 0.229 D 302.0 282.0 8 31 31 0 [[583, 847], [875, 1151]] 2.0 4ehz TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1

PDB: 4EHZ — TYR JAK1_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 4 100.0% 4EHZA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK1-2 JAK1_HUMAN 4EHZA P23458 858 1154 1154.0 JAK:1201 Type1 Inactive DFGin 6.2945 13.63 ABAminus -122.46, 12.74 -158.91, 149.59 -139.33, 23.83 295.89, 89.08 -61.4, -20.25 in-in in 7.7955 Saltbr-in 2.9362 HRD-in -79.41, -51.26 80.05, -0.3 in-in-out SNCiio in-out ActLoopNT-in 2.8662 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -94.49, 24.25 APE9-dihe-in -61.79, 133.39 APE8-dihe-in -76.86, 73.91 APE8-rot-na 30.52 APE67-dihe-in -75.94, -6.94 -60.76, -27.83 APE12-dist-na 11.4383 APE11-dist-na 13.1596 APE10-dist-na 9.8707 APE9-dist-in 7.0319 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 2.174 0.174 0.229 A 302.0 292.0 5 31 31 0 [[583, 847], [875, 1151]] 2.0 4ehz Homo sapiens TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4EHZB P23458 865 1154 1154.0 JAK:1201 Type1 Inactive DFGin 6.3175 13.7298 ABAminus -116.35, 3.51 -150.61, 148.16 -138.87, 32.34 292.95, 86.02 -67.41, -23.21 in-in in 7.8685 Saltbr-in 2.7634 HRD-in -83.57, -44.01 70.15, -1.08 in-in-out SNCiio in-out ActLoopNT-in 2.7334 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -104.9, 29.19 APE9-dihe-in -67.89, 136.88 APE8-dihe-in -75.68, 68.81 APE8-rot-na 33.04 APE67-dihe-in -71.9, -6.58 -49.99, -36.99 APE12-dist-na 11.4195 APE11-dist-na 13.393 APE10-dist-na 10.1247 APE9-dist-in 6.9909 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 2.174 0.174 0.229 B 302.0 282.0 8 31 31 0 [[583, 847], [875, 1151]] 2.0 4ehz Homo sapiens TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4EHZC P23458 866 1154 1154.0 JAK:1201 Type1 Inactive DFGin 6.3172 13.6208 ABAminus -118.15, 8.14 -148.22, 154.09 -141.74, 25.14 292.74, 84.54 -60.05, -18.24 in-in in 7.8585 Saltbr-in 2.8403 HRD-in -77.85, -48.09 78.3, 3.1 in-in-out SNCiio in-out ActLoopNT-in 2.7238 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -117.81, 30.11 APE9-dihe-in -57.01, 145.43 APE8-dihe-in -85.32, 74.95 APE8-rot-na 31.15 APE67-dihe-in -74.27, -3.28 -56.74, -31.49 APE12-dist-na 10.9751 APE11-dist-na 13.0044 APE10-dist-na 10.1803 APE9-dist-in 6.676 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 2.174 0.174 0.229 C 302.0 280.0 9 31 31 0 [[583, 847], [875, 1151]] 2.0 4ehz Homo sapiens TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4EHZD P23458 865 1154 1154.0 JAK:1201 Type1 Inactive DFGin 6.4285 13.533 ABAminus -123.86, 16.47 -158.34, 146.22 -137.38, 32.15 296.06, 77.8 -67.83, -20.15 in-in in 7.6786 Saltbr-in 2.9996 HRD-in -85.88, -43.73 70.18, 7.9 in-in-out SNCiio in-out ActLoopNT-in 2.8 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -108.38, 26.48 APE9-dihe-in -59.77, 138.32 APE8-dihe-in -81.72, 74.58 APE8-rot-na 32.67 APE67-dihe-in -77.67, -4.82 -52.47, -31.56 APE12-dist-na 11.0435 APE11-dist-na 12.9621 APE10-dist-na 10.0088 APE9-dist-in 6.6881 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 2.174 0.174 0.229 D 302.0 282.0 8 31 31 0 [[583, 847], [875, 1151]] 2.0 4ehz Homo sapiens TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1

PDB: 4EHZ — TYR JAK1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name