PDB: 4AE9 — AGC KAPCA_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 4AE9A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AGC PRKACA KAPCA_HUMAN 4AE9A P17612 13 351 351.0 No_ligand No_ligand Inactive DFGin 6.55 16.001 ABAminus -108.08, 1.25 -143.04, 135.02 -120.31, 26.17 277.62, 67.12 -50.31, -36.29 out-out out 10.2017 Saltbr-out 4.9285 HRD-in -78.87, -60.3 78.37, 10.3 out-in-in SNCoii in-in ActLoopNT-in 2.7466 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -155.01, 163.39 APE9-dihe-na 112.23, 171.54 APE8-dihe-in -84.52, 127.75 APE8-rot-in 289.6 APE67-dihe-in -56.88, -27.79 -43.6, -44.81 APE12-dist-in 8.2704 APE11-dist-in 11.576 APE10-dist-in 6.0269 APE9-dist-in 4.1577 None SEP140,TPO198,SEP339 SEP140,TPO198,SEP339 XRAY 2.3 0.201 0.264 A 343.0 324.0 0 25 25 0 [[44, 298]] 1.0 4ae9 AGC_PRKACA_HUMAN AGC 4.2e-95 323.8 1.0 260.0 260.0 184 185 186 188 190 73 92 96 164 166 165 167.0 221 209 204 203 202 201 200 199 198 122 cAMP-dependent protein kinase catalytic subunit alpha
AGC PRKACA KAPCA_HUMAN 4AE9B P17612 16 351 351.0 No_ligand No_ligand Inactive DFGin 6.7487 16.1613 ABAminus -114.92, -7.43 -130.92, 125.97 -130.48, 16.95 295.44, 81.38 -52.61, -39.79 out-out out 10.6681 Saltbr-out 4.4397 HRD-in -74.27, -49.34 44.92, 35.44 out-in-out SNCoio in-out ActLoopNT-in 2.6317 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -139.93, 157.79 APE9-dihe-na 109.15, 156.62 APE8-dihe-in -68.62, 140.66 APE8-rot-out 10.98 APE67-dihe-in -51.62, -27.57 -42.37, -51.96 APE12-dist-in 8.5473 APE11-dist-in 11.4951 APE10-dist-in 5.9265 APE9-dist-in 4.357 None SEP140,TPO198,SEP339 SEP140,TPO198,SEP339 XRAY 2.3 0.201 0.264 B 343.0 324.0 0 25 25 0 [[44, 298]] 1.0 4ae9 AGC_PRKACA_HUMAN AGC 4.2e-95 323.8 1.0 260.0 260.0 184 185 186 188 190 73 92 96 164 166 165 167.0 221 209 204 203 202 201 200 199 198 122 cAMP-dependent protein kinase catalytic subunit alpha

PDB: 4AE9 — AGC KAPCA_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 4AE9A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AGC PRKACA KAPCA_HUMAN 4AE9A P17612 13 351 351.0 No_ligand No_ligand Inactive DFGin 6.55 16.001 ABAminus -108.08, 1.25 -143.04, 135.02 -120.31, 26.17 277.62, 67.12 -50.31, -36.29 out-out out 10.2017 Saltbr-out 4.9285 HRD-in -78.87, -60.3 78.37, 10.3 out-in-in SNCoii in-in ActLoopNT-in 2.7466 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -155.01, 163.39 APE9-dihe-na 112.23, 171.54 APE8-dihe-in -84.52, 127.75 APE8-rot-in 289.6 APE67-dihe-in -56.88, -27.79 -43.6, -44.81 APE12-dist-in 8.2704 APE11-dist-in 11.576 APE10-dist-in 6.0269 APE9-dist-in 4.1577 None SEP140,TPO198,SEP339 SEP140,TPO198,SEP339 XRAY 2.3 0.201 0.264 A 343.0 324.0 0 25 25 0 [[44, 298]] 1.0 4ae9 Homo sapiens AGC_PRKACA_HUMAN AGC 4.2e-95 323.8 1.0 260.0 260.0 184 185 186 188 190 73 92 96 164 166 165 167.0 221 209 204 203 202 201 200 199 198 122 cAMP-dependent protein kinase catalytic subunit alpha
AGC PRKACA KAPCA_HUMAN 4AE9B P17612 16 351 351.0 No_ligand No_ligand Inactive DFGin 6.7487 16.1613 ABAminus -114.92, -7.43 -130.92, 125.97 -130.48, 16.95 295.44, 81.38 -52.61, -39.79 out-out out 10.6681 Saltbr-out 4.4397 HRD-in -74.27, -49.34 44.92, 35.44 out-in-out SNCoio in-out ActLoopNT-in 2.6317 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -139.93, 157.79 APE9-dihe-na 109.15, 156.62 APE8-dihe-in -68.62, 140.66 APE8-rot-out 10.98 APE67-dihe-in -51.62, -27.57 -42.37, -51.96 APE12-dist-in 8.5473 APE11-dist-in 11.4951 APE10-dist-in 5.9265 APE9-dist-in 4.357 None SEP140,TPO198,SEP339 SEP140,TPO198,SEP339 XRAY 2.3 0.201 0.264 B 343.0 324.0 0 25 25 0 [[44, 298]] 1.0 4ae9 Homo sapiens AGC_PRKACA_HUMAN AGC 4.2e-95 323.8 1.0 260.0 260.0 184 185 186 188 190 73 92 96 164 166 165 167.0 221 209 204 203 202 201 200 199 198 122 cAMP-dependent protein kinase catalytic subunit alpha

PDB: 4AE9 — AGC KAPCA_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name