PDB: 4AE6 — AGC KAPCA_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 4AE6A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AGC PRKACA KAPCA_HUMAN 4AE6A P17612 13 351 351.0 No_ligand No_ligand Inactive DFGin 6.5333 15.789 ABAminus -102.0, -12.32 -149.9, 117.63 -105.31, 23.09 271.72, 75.39 -56.8, -39.15 out-in out 10.0651 Saltbr-in 3.037 HRD-in -80.45, -57.48 71.85, 11.08 in-in-out SNCiio in-out ActLoopNT-in 2.8103 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -156.83, 165.09 APE9-dihe-na 109.71, 150.17 APE8-dihe-in -70.25, 136.52 APE8-rot-out 76.9 APE67-dihe-in -62.21, -26.49 -48.12, -39.36 APE12-dist-in 8.4839 APE11-dist-in 11.6198 APE10-dist-in 6.1388 APE9-dist-in 4.2493 None TPO198,SEP339 TPO198,SEP339 XRAY 2.1 0.219 0.283 A 343.0 321.0 0 25 25 0 [[44, 298]] 1.0 4ae6 AGC_PRKACA_HUMAN AGC 4.2e-95 323.8 1.0 260.0 260.0 184 185 186 188 190 73 92 96 164 166 165 167.0 221 209 204 203 202 201 200 199 198 122 cAMP-dependent protein kinase catalytic subunit alpha
AGC PRKACA KAPCA_HUMAN 4AE6B P17612 17 351 351.0 No_ligand No_ligand Inactive DFGin 6.7262 16.2285 ABAminus -110.11, -21.15 -129.5, 123.25 -122.94, 15.22 289.43, 78.48 -49.18, -40.14 out-out out 10.4783 Saltbr-out 4.4043 HRD-in -72.54, -54.34 51.9, 34.46 out-in-out SNCoio in-out ActLoopNT-in 2.6982 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -140.57, 163.72 APE9-dihe-na 111.27, 158.24 APE8-dihe-in -83.25, 146.52 APE8-rot-out 46.71 APE67-dihe-in -47.41, -26.35 -55.51, -46.4 APE12-dist-in 8.738 APE11-dist-in 11.4408 APE10-dist-in 5.9066 APE9-dist-in 4.36 None TPO198,SEP339 TPO198,SEP339 XRAY 2.1 0.219 0.283 B 343.0 323.0 0 25 25 0 [[44, 298]] 1.0 4ae6 AGC_PRKACA_HUMAN AGC 4.2e-95 323.8 1.0 260.0 260.0 184 185 186 188 190 73 92 96 164 166 165 167.0 221 209 204 203 202 201 200 199 198 122 cAMP-dependent protein kinase catalytic subunit alpha

PDB: 4AE6 — AGC KAPCA_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 4AE6A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AGC PRKACA KAPCA_HUMAN 4AE6A P17612 13 351 351.0 No_ligand No_ligand Inactive DFGin 6.5333 15.789 ABAminus -102.0, -12.32 -149.9, 117.63 -105.31, 23.09 271.72, 75.39 -56.8, -39.15 out-in out 10.0651 Saltbr-in 3.037 HRD-in -80.45, -57.48 71.85, 11.08 in-in-out SNCiio in-out ActLoopNT-in 2.8103 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -156.83, 165.09 APE9-dihe-na 109.71, 150.17 APE8-dihe-in -70.25, 136.52 APE8-rot-out 76.9 APE67-dihe-in -62.21, -26.49 -48.12, -39.36 APE12-dist-in 8.4839 APE11-dist-in 11.6198 APE10-dist-in 6.1388 APE9-dist-in 4.2493 None TPO198,SEP339 TPO198,SEP339 XRAY 2.1 0.219 0.283 A 343.0 321.0 0 25 25 0 [[44, 298]] 1.0 4ae6 Homo sapiens AGC_PRKACA_HUMAN AGC 4.2e-95 323.8 1.0 260.0 260.0 184 185 186 188 190 73 92 96 164 166 165 167.0 221 209 204 203 202 201 200 199 198 122 cAMP-dependent protein kinase catalytic subunit alpha
AGC PRKACA KAPCA_HUMAN 4AE6B P17612 17 351 351.0 No_ligand No_ligand Inactive DFGin 6.7262 16.2285 ABAminus -110.11, -21.15 -129.5, 123.25 -122.94, 15.22 289.43, 78.48 -49.18, -40.14 out-out out 10.4783 Saltbr-out 4.4043 HRD-in -72.54, -54.34 51.9, 34.46 out-in-out SNCoio in-out ActLoopNT-in 2.6982 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -140.57, 163.72 APE9-dihe-na 111.27, 158.24 APE8-dihe-in -83.25, 146.52 APE8-rot-out 46.71 APE67-dihe-in -47.41, -26.35 -55.51, -46.4 APE12-dist-in 8.738 APE11-dist-in 11.4408 APE10-dist-in 5.9066 APE9-dist-in 4.36 None TPO198,SEP339 TPO198,SEP339 XRAY 2.1 0.219 0.283 B 343.0 323.0 0 25 25 0 [[44, 298]] 1.0 4ae6 Homo sapiens AGC_PRKACA_HUMAN AGC 4.2e-95 323.8 1.0 260.0 260.0 184 185 186 188 190 73 92 96 164 166 165 167.0 221 209 204 203 202 201 200 199 198 122 cAMP-dependent protein kinase catalytic subunit alpha

PDB: 4AE6 — AGC KAPCA_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name