PDB: 3ENM — STE MP2K6_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 4 100.0% 3ENMA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K6 MP2K6_HUMAN 3ENMA P52564 46 332 334.0 No_ligand No_ligand Inactive DFGin 7.2057 11.561 None -72.54, 127.3 -73.54, -5.06 -145.36, 172.63 75.39, 93.79 -81.87, 71.68 out-na out 14.7786 Saltbr-na 19.7289 HRD-in -62.52, -52.47 78.76, -8.63 na-out-none SNCaon out-none ActLoopNT-out 14.8184 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none -69.11, 104.97 999.0, -79.37 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 S207D,T211D None MSE57,MSE70,MSE79,MSE98,MSE104,MSE129,MSE132,MSE195,MSE220,MSE247,MSE309 XRAY 2.35 0.215 0.269 A 316.0 278.0 9 27 18 9 [[53, 314]] 1.0 3enm STE_MAP2K6_HUMAN STE 5.1e-85 290.9 3.0 257.0 255.0 196 197 198 200 202 82 99 103 176 178 177 179.0 239 223 218 217 216 215 214 213 212 130 Dual specificity mitogen-activated protein kinase kinase 6
STE MAP2K6 MP2K6_HUMAN 3ENMB P52564 49 332 334.0 No_ligand No_ligand Inactive DFGin 6.4336 11.873 None -76.15, 120.81 -66.53, 1.54 -153.84, 168.39 61.21, 99.4 -71.06, 67.13 out-na out 15.0002 Saltbr-na 20.0247 HRD-in -64.57, -50.97 79.15, -4.28 na-out-none SNCaon out-none ActLoopNT-out 14.4809 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none -73.08, 113.2 999.0, -108.84 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 S207D,T211D None MSE57,MSE70,MSE79,MSE98,MSE104,MSE129,MSE132,MSE195,MSE220,MSE247,MSE309 XRAY 2.35 0.215 0.269 B 316.0 271.0 13 27 19 8 [[53, 314]] 1.0 3enm STE_MAP2K6_HUMAN STE 5.1e-85 290.9 3.0 257.0 255.0 196 197 198 200 202 82 99 103 176 178 177 179.0 239 223 218 217 216 215 214 213 212 130 Dual specificity mitogen-activated protein kinase kinase 6
STE MAP2K6 MP2K6_HUMAN 3ENMC P52564 48 332 334.0 No_ligand No_ligand Inactive DFGin 6.8007 11.7267 None -62.87, 122.88 -68.86, -8.42 -137.51, 177.55 64.57, 100.37 -78.87, 64.07 out-na out 14.8261 Saltbr-na 19.8254 HRD-in -65.29, -57.18 66.82, -2.67 na-out-none SNCaon out-none ActLoopNT-out 14.5147 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none -82.6, 107.52 999.0, -65.96 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 S207D,T211D None MSE57,MSE70,MSE79,MSE98,MSE104,MSE129,MSE132,MSE195,MSE220,MSE247,MSE309 XRAY 2.35 0.215 0.269 C 316.0 274.0 11 27 19 8 [[53, 314]] 1.0 3enm STE_MAP2K6_HUMAN STE 5.1e-85 290.9 3.0 257.0 255.0 196 197 198 200 202 82 99 103 176 178 177 179.0 239 223 218 217 216 215 214 213 212 130 Dual specificity mitogen-activated protein kinase kinase 6
STE MAP2K6 MP2K6_HUMAN 3ENMD P52564 45 332 334.0 No_ligand No_ligand Inactive DFGin 6.8746 11.4777 None -70.65, 125.17 -79.65, 11.99 -158.34, 166.38 66.09, 89.82 -77.06, 78.99 out-na out 14.5686 Saltbr-na 19.5439 HRD-in -56.29, -53.91 80.33, -16.21 na-out-none SNCaon out-none ActLoopNT-out 14.8567 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none -80.61, 127.32 999.0, -136.25 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 S207D,T211D None MSE57,MSE70,MSE79,MSE98,MSE104,MSE129,MSE132,MSE195,MSE220,MSE247,MSE309 XRAY 2.35 0.215 0.269 D 316.0 279.0 9 27 18 9 [[53, 314]] 1.0 3enm STE_MAP2K6_HUMAN STE 5.1e-85 290.9 3.0 257.0 255.0 196 197 198 200 202 82 99 103 176 178 177 179.0 239 223 218 217 216 215 214 213 212 130 Dual specificity mitogen-activated protein kinase kinase 6

PDB: 3ENM — STE MP2K6_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 4 100.0% 3ENMA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP2K6 MP2K6_HUMAN 3ENMA P52564 46 332 334.0 No_ligand No_ligand Inactive DFGin 7.2057 11.561 None -72.54, 127.3 -73.54, -5.06 -145.36, 172.63 75.39, 93.79 -81.87, 71.68 out-na out 14.7786 Saltbr-na 19.7289 HRD-in -62.52, -52.47 78.76, -8.63 na-out-none SNCaon out-none ActLoopNT-out 14.8184 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none -69.11, 104.97 999.0, -79.37 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 S207D,T211D None MSE57,MSE70,MSE79,MSE98,MSE104,MSE129,MSE132,MSE195,MSE220,MSE247,MSE309 XRAY 2.35 0.215 0.269 A 316.0 278.0 9 27 18 9 [[53, 314]] 1.0 3enm Homo sapiens STE_MAP2K6_HUMAN STE 5.1e-85 290.9 3.0 257.0 255.0 196 197 198 200 202 82 99 103 176 178 177 179.0 239 223 218 217 216 215 214 213 212 130 Dual specificity mitogen-activated protein kinase kinase 6
STE MAP2K6 MP2K6_HUMAN 3ENMB P52564 49 332 334.0 No_ligand No_ligand Inactive DFGin 6.4336 11.873 None -76.15, 120.81 -66.53, 1.54 -153.84, 168.39 61.21, 99.4 -71.06, 67.13 out-na out 15.0002 Saltbr-na 20.0247 HRD-in -64.57, -50.97 79.15, -4.28 na-out-none SNCaon out-none ActLoopNT-out 14.4809 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none -73.08, 113.2 999.0, -108.84 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 S207D,T211D None MSE57,MSE70,MSE79,MSE98,MSE104,MSE129,MSE132,MSE195,MSE220,MSE247,MSE309 XRAY 2.35 0.215 0.269 B 316.0 271.0 13 27 19 8 [[53, 314]] 1.0 3enm Homo sapiens STE_MAP2K6_HUMAN STE 5.1e-85 290.9 3.0 257.0 255.0 196 197 198 200 202 82 99 103 176 178 177 179.0 239 223 218 217 216 215 214 213 212 130 Dual specificity mitogen-activated protein kinase kinase 6
STE MAP2K6 MP2K6_HUMAN 3ENMC P52564 48 332 334.0 No_ligand No_ligand Inactive DFGin 6.8007 11.7267 None -62.87, 122.88 -68.86, -8.42 -137.51, 177.55 64.57, 100.37 -78.87, 64.07 out-na out 14.8261 Saltbr-na 19.8254 HRD-in -65.29, -57.18 66.82, -2.67 na-out-none SNCaon out-none ActLoopNT-out 14.5147 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none -82.6, 107.52 999.0, -65.96 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 S207D,T211D None MSE57,MSE70,MSE79,MSE98,MSE104,MSE129,MSE132,MSE195,MSE220,MSE247,MSE309 XRAY 2.35 0.215 0.269 C 316.0 274.0 11 27 19 8 [[53, 314]] 1.0 3enm Homo sapiens STE_MAP2K6_HUMAN STE 5.1e-85 290.9 3.0 257.0 255.0 196 197 198 200 202 82 99 103 176 178 177 179.0 239 223 218 217 216 215 214 213 212 130 Dual specificity mitogen-activated protein kinase kinase 6
STE MAP2K6 MP2K6_HUMAN 3ENMD P52564 45 332 334.0 No_ligand No_ligand Inactive DFGin 6.8746 11.4777 None -70.65, 125.17 -79.65, 11.99 -158.34, 166.38 66.09, 89.82 -77.06, 78.99 out-na out 14.5686 Saltbr-na 19.5439 HRD-in -56.29, -53.91 80.33, -16.21 na-out-none SNCaon out-none ActLoopNT-out 14.8567 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none -80.61, 127.32 999.0, -136.25 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 S207D,T211D None MSE57,MSE70,MSE79,MSE98,MSE104,MSE129,MSE132,MSE195,MSE220,MSE247,MSE309 XRAY 2.35 0.215 0.269 D 316.0 279.0 9 27 18 9 [[53, 314]] 1.0 3enm Homo sapiens STE_MAP2K6_HUMAN STE 5.1e-85 290.9 3.0 257.0 255.0 196 197 198 200 202 82 99 103 176 178 177 179.0 239 223 218 217 216 215 214 213 212 130 Dual specificity mitogen-activated protein kinase kinase 6

PDB: 3ENM — STE MP2K6_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name