Hover over column headers for tooltip help
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TKL | IRAK4 | IRAK4_HUMAN | 2NRYC | Q9NWZ3 | 164 | 458 | 460.0 | STU:503 | Type1 | Active | DFGin | 7.396 | 13.991 | BLAminus | -129.87, 177.33 | 66.53, 79.75 | -106.36, 3.08 | 302.75, 99.86 | -41.96, -44.4 | in-in | in | 9.05 | Saltbr-in | 2.876 | HRD-in | -69.99, -46.9 | 74.7, -3.92 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.924 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -134.06, 166.37 | APE9-dihe-na | 122.8, -162.09 | APE8-dihe-in | -122.72, 120.05 | APE8-rot-in | 297.38 | APE67-dihe-in | -61.23, -20.14 | -50.62, -47.6 | APE12-dist-in | 11.845 | APE11-dist-in | 12.224 | APE10-dist-in | 7.0 | APE9-dist-in | 3.864 | None | TPO345 | TPO345 | XRAY | 2.15 | 0.212 | 0.261 | C | 307 | 281 | 14 | 0 | 0 | 4 | [[183, 456]] | 1.0 | 2nry | TKL_IRAK4_HUMAN | TKL | 4.4e-84 | 288.1 | 5 | 266 | 262 | 328 | 329 | 330 | 332 | 334 | 213 | 233 | 237 | 308 | 310 | 309 | 311 | 369 | 358 | 353 | 352 | 351 | 350 | 349 | 348 | 347 | 263 | Interleukin-1 receptor-associated kinase 4 |
| TKL | IRAK4 | IRAK4_HUMAN | 2NRYD | Q9NWZ3 | 164 | 460 | 460.0 | STU:501 | Type1 | Active | DFGin | 7.103 | 14.601 | BLAminus | -126.69, 167.35 | 70.82, 64.69 | -93.05, 43.05 | 345.42, 126.85 | -89.85, -18.2 | in-in | in | 9.176 | Saltbr-in | 2.95 | HRD-in | -59.6, -55.9 | 83.92, -5.49 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.724 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -143.15, 176.95 | APE9-dihe-na | 112.24, -167.34 | APE8-dihe-in | -128.61, 119.15 | APE8-rot-in | 302.8 | APE67-dihe-in | -66.3, -17.75 | -48.9, -47.71 | APE12-dist-in | 10.025 | APE11-dist-in | 11.615 | APE10-dist-in | 6.271 | APE9-dist-in | 3.538 | None | TPO345 | TPO345 | XRAY | 2.15 | 0.212 | 0.261 | D | 307 | 283 | 14 | 0 | 0 | 5 | [[183, 456]] | 1.0 | 2nry | TKL_IRAK4_HUMAN | TKL | 4.4e-84 | 288.1 | 5 | 266 | 262 | 328 | 329 | 330 | 332 | 334 | 213 | 233 | 237 | 308 | 310 | 309 | 311 | 369 | 358 | 353 | 352 | 351 | 350 | 349 | 348 | 347 | 263 | Interleukin-1 receptor-associated kinase 4 |
| TKL | IRAK4 | IRAK4_HUMAN | 2NRYA | Q9NWZ3 | 164 | 458 | 460.0 | STU:504 | Type1 | Inactive | DFGin | 7.039 | 13.85 | BLBminus | -119.68, 177.11 | 59.06, 71.69 | -112.23, -126.05 | 350.98, 70.79 | 78.1, -70.69 | in-in | in | 9.03 | Saltbr-in | 2.758 | HRD-in | -65.27, -50.09 | 77.33, -7.45 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.754 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -126.61, 161.22 | APE9-dihe-na | 128.42, -175.43 | APE8-dihe-in | -120.1, 117.97 | APE8-rot-in | 299.02 | APE67-dihe-in | -57.48, -21.15 | -43.86, -55.05 | APE12-dist-in | 10.988 | APE11-dist-in | 13.053 | APE10-dist-in | 7.67 | APE9-dist-in | 3.682 | None | TPO345 | TPO345 | XRAY | 2.15 | 0.212 | 0.261 | A | 307 | 287 | 8 | 0 | 0 | 5 | [[183, 456]] | 1.0 | 2nry | TKL_IRAK4_HUMAN | TKL | 4.4e-84 | 288.1 | 5 | 266 | 262 | 328 | 329 | 330 | 332 | 334 | 213 | 233 | 237 | 308 | 310 | 309 | 311 | 369 | 358 | 353 | 352 | 351 | 350 | 349 | 348 | 347 | 263 | Interleukin-1 receptor-associated kinase 4 |
| TKL | IRAK4 | IRAK4_HUMAN | 2NRYB | Q9NWZ3 | 164 | 458 | 460.0 | STU:502 | Type1 | Inactive | DFGin | 7.33 | 14.211 | BLBminus | -121.91, 179.32 | 63.59, 83.43 | -104.91, -160.11 | 313.36, 100.13 | 93.41, -69.05 | in-out | in | 8.992 | Saltbr-out | 3.775 | HRD-in | -74.38, -53.26 | 85.42, -10.52 | out-in-in | SNCoii | in-in | ActLoopNT-in | 2.61 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -117.77, 162.03 | APE9-dihe-na | 124.37, -168.49 | APE8-dihe-in | -121.78, 111.1 | APE8-rot-in | 307.1 | APE67-dihe-in | -48.86, -28.56 | -36.36, -56.5 | APE12-dist-in | 9.932 | APE11-dist-in | 12.138 | APE10-dist-in | 6.485 | APE9-dist-in | 3.62 | None | TPO345 | TPO345 | XRAY | 2.15 | 0.212 | 0.261 | B | 307 | 287 | 8 | 0 | 0 | 5 | [[183, 456]] | 1.0 | 2nry | TKL_IRAK4_HUMAN | TKL | 4.4e-84 | 288.1 | 5 | 266 | 262 | 328 | 329 | 330 | 332 | 334 | 213 | 233 | 237 | 308 | 310 | 309 | 311 | 369 | 358 | 353 | 352 | 351 | 350 | 349 | 348 | 347 | 263 | Interleukin-1 receptor-associated kinase 4 |
Hover over column headers for tooltip help
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TKL | IRAK4 | IRAK4_HUMAN | 2NRYC | Q9NWZ3 | 164 | 458 | 460.0 | STU:503 | Type1 | Active | DFGin | 7.396 | 13.991 | BLAminus | -129.87, 177.33 | 66.53, 79.75 | -106.36, 3.08 | 302.75, 99.86 | -41.96, -44.4 | in-in | in | 9.05 | Saltbr-in | 2.876 | HRD-in | -69.99, -46.9 | 74.7, -3.92 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.924 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -134.06, 166.37 | APE9-dihe-na | 122.8, -162.09 | APE8-dihe-in | -122.72, 120.05 | APE8-rot-in | 297.38 | APE67-dihe-in | -61.23, -20.14 | -50.62, -47.6 | APE12-dist-in | 11.845 | APE11-dist-in | 12.224 | APE10-dist-in | 7.0 | APE9-dist-in | 3.864 | None | TPO345 | TPO345 | XRAY | 2.15 | 0.212 | 0.261 | C | 307 | 281 | 14 | 0 | 0 | 4 | [[183, 456]] | 1.0 | 2nry | Homo sapiens | TKL_IRAK4_HUMAN | TKL | 4.4e-84 | 288.1 | 5 | 266 | 262 | 328 | 329 | 330 | 332 | 334 | 213 | 233 | 237 | 308 | 310 | 309 | 311 | 369 | 358 | 353 | 352 | 351 | 350 | 349 | 348 | 347 | 263 | Interleukin-1 receptor-associated kinase 4 |
| TKL | IRAK4 | IRAK4_HUMAN | 2NRYD | Q9NWZ3 | 164 | 460 | 460.0 | STU:501 | Type1 | Active | DFGin | 7.103 | 14.601 | BLAminus | -126.69, 167.35 | 70.82, 64.69 | -93.05, 43.05 | 345.42, 126.85 | -89.85, -18.2 | in-in | in | 9.176 | Saltbr-in | 2.95 | HRD-in | -59.6, -55.9 | 83.92, -5.49 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.724 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -143.15, 176.95 | APE9-dihe-na | 112.24, -167.34 | APE8-dihe-in | -128.61, 119.15 | APE8-rot-in | 302.8 | APE67-dihe-in | -66.3, -17.75 | -48.9, -47.71 | APE12-dist-in | 10.025 | APE11-dist-in | 11.615 | APE10-dist-in | 6.271 | APE9-dist-in | 3.538 | None | TPO345 | TPO345 | XRAY | 2.15 | 0.212 | 0.261 | D | 307 | 283 | 14 | 0 | 0 | 5 | [[183, 456]] | 1.0 | 2nry | Homo sapiens | TKL_IRAK4_HUMAN | TKL | 4.4e-84 | 288.1 | 5 | 266 | 262 | 328 | 329 | 330 | 332 | 334 | 213 | 233 | 237 | 308 | 310 | 309 | 311 | 369 | 358 | 353 | 352 | 351 | 350 | 349 | 348 | 347 | 263 | Interleukin-1 receptor-associated kinase 4 |
| TKL | IRAK4 | IRAK4_HUMAN | 2NRYA | Q9NWZ3 | 164 | 458 | 460.0 | STU:504 | Type1 | Inactive | DFGin | 7.039 | 13.85 | BLBminus | -119.68, 177.11 | 59.06, 71.69 | -112.23, -126.05 | 350.98, 70.79 | 78.1, -70.69 | in-in | in | 9.03 | Saltbr-in | 2.758 | HRD-in | -65.27, -50.09 | 77.33, -7.45 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.754 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -126.61, 161.22 | APE9-dihe-na | 128.42, -175.43 | APE8-dihe-in | -120.1, 117.97 | APE8-rot-in | 299.02 | APE67-dihe-in | -57.48, -21.15 | -43.86, -55.05 | APE12-dist-in | 10.988 | APE11-dist-in | 13.053 | APE10-dist-in | 7.67 | APE9-dist-in | 3.682 | None | TPO345 | TPO345 | XRAY | 2.15 | 0.212 | 0.261 | A | 307 | 287 | 8 | 0 | 0 | 5 | [[183, 456]] | 1.0 | 2nry | Homo sapiens | TKL_IRAK4_HUMAN | TKL | 4.4e-84 | 288.1 | 5 | 266 | 262 | 328 | 329 | 330 | 332 | 334 | 213 | 233 | 237 | 308 | 310 | 309 | 311 | 369 | 358 | 353 | 352 | 351 | 350 | 349 | 348 | 347 | 263 | Interleukin-1 receptor-associated kinase 4 |
| TKL | IRAK4 | IRAK4_HUMAN | 2NRYB | Q9NWZ3 | 164 | 458 | 460.0 | STU:502 | Type1 | Inactive | DFGin | 7.33 | 14.211 | BLBminus | -121.91, 179.32 | 63.59, 83.43 | -104.91, -160.11 | 313.36, 100.13 | 93.41, -69.05 | in-out | in | 8.992 | Saltbr-out | 3.775 | HRD-in | -74.38, -53.26 | 85.42, -10.52 | out-in-in | SNCoii | in-in | ActLoopNT-in | 2.61 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -117.77, 162.03 | APE9-dihe-na | 124.37, -168.49 | APE8-dihe-in | -121.78, 111.1 | APE8-rot-in | 307.1 | APE67-dihe-in | -48.86, -28.56 | -36.36, -56.5 | APE12-dist-in | 9.932 | APE11-dist-in | 12.138 | APE10-dist-in | 6.485 | APE9-dist-in | 3.62 | None | TPO345 | TPO345 | XRAY | 2.15 | 0.212 | 0.261 | B | 307 | 287 | 8 | 0 | 0 | 5 | [[183, 456]] | 1.0 | 2nry | Homo sapiens | TKL_IRAK4_HUMAN | TKL | 4.4e-84 | 288.1 | 5 | 266 | 262 | 328 | 329 | 330 | 332 | 334 | 213 | 233 | 237 | 308 | 310 | 309 | 311 | 369 | 358 | 353 | 352 | 351 | 350 | 349 | 348 | 347 | 263 | Interleukin-1 receptor-associated kinase 4 |
| Spatial label | Dihedral label | Number of Chains | Percent | Representative |
|---|
Hover over column headers for tooltip help
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|