PDB: 1U46 — TYR ACK1_HUMAN

Total number of chains: 2
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 1 50.0% 1U46A
DFGin BLAminus 1 50.0% 1U46B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR TNK2 ACK1_HUMAN 1U46A Q07912 117 389 1038.0 No_ligand No_ligand Inactive DFGin 6.6774 13.6062 ABAminus -105.04, -15.76 -135.27, 148.5 -140.73, 24.35 300.72, 95.61 -66.87, -16.87 in-in in 8.88 Saltbr-in 3.0421 HRD-in -74.47, -45.94 65.29, 8.06 in-in-none SNCiin in-none ActLoopNT-in 3.0797 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 148.6 APE8-dihe-in -40.6, 125.73 APE8-rot-na 326.91 APE67-dihe-in -63.61, -22.03 -68.77, -33.68 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 5.4874 None None None XRAY 2.0 0.202 0.249 A 291.0 255.0 18 31 25 6 [[126, 387]] 1.0 1u46 TYR_TNK2_HUMAN TYR 9e-86 293.3 1.0 259.0 259.0 269 270 271 273 275 158 177 181 249 251 250 252.0 312 300 295 294 293 292 291 290 289 206 Activated CDC42 kinase 1
TYR TNK2 ACK1_HUMAN 1U46B Q07912 117 390 1038.0 No_ligand No_ligand Active DFGin 6.8929 13.3269 BLAminus -106.75, -162.4 39.69, 86.16 -96.94, 26.22 299.15, 109.43 -73.67, -16.41 in-in in 8.1814 Saltbr-in 2.5893 HRD-in -73.19, -48.75 76.75, -0.65 in-in-in SNCiii in-in ActLoopNT-in 2.9211 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -148.81, 131.4 APE9-dihe-in -119.81, 131.46 APE8-dihe-in -52.5, 137.43 APE8-rot-na 348.53 APE67-dihe-in -65.13, -16.63 -61.62, -36.89 APE12-dist-na 12.2376 APE11-dist-na 7.1908 APE10-dist-na 10.2147 APE9-dist-in 5.6432 None None None XRAY 2.0 0.202 0.249 B 291.0 257.0 17 31 31 0 [[126, 387]] 1.0 1u46 TYR_TNK2_HUMAN TYR 9e-86 293.3 1.0 259.0 259.0 269 270 271 273 275 158 177 181 249 251 250 252.0 312 300 295 294 293 292 291 290 289 206 Activated CDC42 kinase 1

PDB: 1U46 — TYR ACK1_HUMAN

Total number of chains: 2
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 1 50.0% 1U46A
DFGin BLAminus 1 50.0% 1U46B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR TNK2 ACK1_HUMAN 1U46A Q07912 117 389 1038.0 No_ligand No_ligand Inactive DFGin 6.6774 13.6062 ABAminus -105.04, -15.76 -135.27, 148.5 -140.73, 24.35 300.72, 95.61 -66.87, -16.87 in-in in 8.88 Saltbr-in 3.0421 HRD-in -74.47, -45.94 65.29, 8.06 in-in-none SNCiin in-none ActLoopNT-in 3.0797 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 148.6 APE8-dihe-in -40.6, 125.73 APE8-rot-na 326.91 APE67-dihe-in -63.61, -22.03 -68.77, -33.68 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 5.4874 None None None XRAY 2.0 0.202 0.249 A 291.0 255.0 18 31 25 6 [[126, 387]] 1.0 1u46 Homo sapiens TYR_TNK2_HUMAN TYR 9e-86 293.3 1.0 259.0 259.0 269 270 271 273 275 158 177 181 249 251 250 252.0 312 300 295 294 293 292 291 290 289 206 Activated CDC42 kinase 1
TYR TNK2 ACK1_HUMAN 1U46B Q07912 117 390 1038.0 No_ligand No_ligand Active DFGin 6.8929 13.3269 BLAminus -106.75, -162.4 39.69, 86.16 -96.94, 26.22 299.15, 109.43 -73.67, -16.41 in-in in 8.1814 Saltbr-in 2.5893 HRD-in -73.19, -48.75 76.75, -0.65 in-in-in SNCiii in-in ActLoopNT-in 2.9211 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -148.81, 131.4 APE9-dihe-in -119.81, 131.46 APE8-dihe-in -52.5, 137.43 APE8-rot-na 348.53 APE67-dihe-in -65.13, -16.63 -61.62, -36.89 APE12-dist-na 12.2376 APE11-dist-na 7.1908 APE10-dist-na 10.2147 APE9-dist-in 5.6432 None None None XRAY 2.0 0.202 0.249 B 291.0 257.0 17 31 31 0 [[126, 387]] 1.0 1u46 Homo sapiens TYR_TNK2_HUMAN TYR 9e-86 293.3 1.0 259.0 259.0 269 270 271 273 275 158 177 181 249 251 250 252.0 312 300 295 294 293 292 291 290 289 206 Activated CDC42 kinase 1

PDB: 1U46 — TYR ACK1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name