PDB: 1IAS — TKL TGFR1_HUMAN

Total number of chains: 5
Active chains: 5
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 5 100.0% 1IASA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL TGFBR1 TGFR1_HUMAN 1IASA P36897 171 500 503.0 No_ligand No_ligand Active DFGin 6.721 12.723 BLAminus -151.41, 164.95 71.98, 88.97 -106.86, 22.49 311.89, 1.41 -60.78, -26.26 in-in in 8.24 Saltbr-in 2.79 HRD-in -63.37, -49.76 71.64, 8.78 in-in-in SNCiii in-in ActLoopNT-in 2.974 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -146.42, 172.85 APE9-dihe-na 97.41, 166.83 APE8-dihe-in -62.29, 121.18 APE8-rot-in 307.67 APE67-dihe-in -45.67, -30.78 -49.33, -54.47 APE12-dist-in 11.452 APE11-dist-in 11.629 APE10-dist-in 6.172 APE9-dist-in 4.131 None None None XRAY 2.9 0.255 0.284 A 342 330 0 0 0 0 [[205, 494]] 1.0 1ias TKL_TGFBR1_HUMAN TKL 4.9e-85 291.2 3 266 264 350 351 352 354 356 232 245 249 330 332 331 333 400 382 377 376 375 374 373 372 371 281 TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 1IASB P36897 171 501 503.0 No_ligand No_ligand Active DFGin 6.652 12.707 BLAminus -150.79, 165.66 71.53, 88.91 -106.55, 22.01 312.14, 1.23 -60.97, -25.51 in-in in 8.241 Saltbr-in 2.799 HRD-in -64.38, -48.85 71.21, 7.9 in-in-in SNCiii in-in ActLoopNT-in 3.005 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -128.79, 173.68 APE9-dihe-na 99.72, 167.49 APE8-dihe-in -63.26, 121.22 APE8-rot-in 308.35 APE67-dihe-in -44.49, -32.42 -49.46, -55.33 APE12-dist-in 10.321 APE11-dist-in 11.628 APE10-dist-in 6.241 APE9-dist-in 4.05 None None None XRAY 2.9 0.255 0.284 B 342 324 7 0 0 3 [[205, 494]] 1.0 1ias TKL_TGFBR1_HUMAN TKL 4.9e-85 291.2 3 266 264 350 351 352 354 356 232 245 249 330 332 331 333 400 382 377 376 375 374 373 372 371 281 TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 1IASC P36897 171 500 503.0 No_ligand No_ligand Active DFGin 6.59 12.711 BLAminus -150.31, 164.7 71.4, 89.07 -106.94, 23.22 312.6, 1.77 -61.3, -25.67 in-in in 8.197 Saltbr-in 2.799 HRD-in -63.0, -50.37 71.83, 9.79 in-in-in SNCiii in-in ActLoopNT-in 3.013 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -119.75, 170.21 APE9-dihe-na 100.55, 167.25 APE8-dihe-in -63.65, 121.53 APE8-rot-in 308.64 APE67-dihe-in -44.33, -30.7 -49.24, -56.44 APE12-dist-in 11.349 APE11-dist-in 11.759 APE10-dist-in 6.222 APE9-dist-in 4.15 None None None XRAY 2.9 0.255 0.284 C 342 330 0 0 0 0 [[205, 494]] 1.0 1ias TKL_TGFBR1_HUMAN TKL 4.9e-85 291.2 3 266 264 350 351 352 354 356 232 245 249 330 332 331 333 400 382 377 376 375 374 373 372 371 281 TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 1IASD P36897 171 500 503.0 No_ligand No_ligand Active DFGin 6.594 12.743 BLAminus -152.15, 165.79 70.83, 87.83 -105.27, 21.55 312.92, 0.98 -60.27, -25.54 in-in in 8.189 Saltbr-in 2.775 HRD-in -64.51, -48.18 71.39, 8.63 in-in-in SNCiii in-in ActLoopNT-in 2.993 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -131.69, 169.96 APE9-dihe-na 98.27, 166.26 APE8-dihe-in -61.5, 120.34 APE8-rot-in 308.37 APE67-dihe-in -44.16, -31.51 -48.36, -56.13 APE12-dist-in 10.732 APE11-dist-in 11.784 APE10-dist-in 6.18 APE9-dist-in 4.04 None None None XRAY 2.9 0.255 0.284 D 342 330 0 0 0 0 [[205, 494]] 1.0 1ias TKL_TGFBR1_HUMAN TKL 4.9e-85 291.2 3 266 264 350 351 352 354 356 232 245 249 330 332 331 333 400 382 377 376 375 374 373 372 371 281 TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 1IASE P36897 171 500 503.0 No_ligand No_ligand Active DFGin 6.685 12.738 BLAminus -151.39, 165.15 70.82, 89.42 -106.94, 21.97 311.98, 2.05 -61.66, -24.41 in-in in 8.226 Saltbr-in 2.803 HRD-in -61.95, -50.33 72.19, 7.85 in-in-in SNCiii in-in ActLoopNT-in 3.008 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -127.31, 173.9 APE9-dihe-na 98.05, 167.39 APE8-dihe-in -64.1, 121.3 APE8-rot-in 308.19 APE67-dihe-in -45.93, -31.42 -49.14, -54.62 APE12-dist-in 11.636 APE11-dist-in 11.505 APE10-dist-in 6.149 APE9-dist-in 4.002 None None None XRAY 2.9 0.255 0.284 E 342 330 0 0 0 0 [[205, 494]] 1.0 1ias TKL_TGFBR1_HUMAN TKL 4.9e-85 291.2 3 266 264 350 351 352 354 356 232 245 249 330 332 331 333 400 382 377 376 375 374 373 372 371 281 TGF-beta receptor type-1

PDB: 1IAS — TKL TGFR1_HUMAN

Total number of chains: 5
Active chains: 5
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 5 100.0% 1IASA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL TGFBR1 TGFR1_HUMAN 1IASA P36897 171 500 503.0 No_ligand No_ligand Active DFGin 6.721 12.723 BLAminus -151.41, 164.95 71.98, 88.97 -106.86, 22.49 311.89, 1.41 -60.78, -26.26 in-in in 8.24 Saltbr-in 2.79 HRD-in -63.37, -49.76 71.64, 8.78 in-in-in SNCiii in-in ActLoopNT-in 2.974 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -146.42, 172.85 APE9-dihe-na 97.41, 166.83 APE8-dihe-in -62.29, 121.18 APE8-rot-in 307.67 APE67-dihe-in -45.67, -30.78 -49.33, -54.47 APE12-dist-in 11.452 APE11-dist-in 11.629 APE10-dist-in 6.172 APE9-dist-in 4.131 None None None XRAY 2.9 0.255 0.284 A 342 330 0 0 0 0 [[205, 494]] 1.0 1ias Homo sapiens TKL_TGFBR1_HUMAN TKL 4.9e-85 291.2 3 266 264 350 351 352 354 356 232 245 249 330 332 331 333 400 382 377 376 375 374 373 372 371 281 TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 1IASB P36897 171 501 503.0 No_ligand No_ligand Active DFGin 6.652 12.707 BLAminus -150.79, 165.66 71.53, 88.91 -106.55, 22.01 312.14, 1.23 -60.97, -25.51 in-in in 8.241 Saltbr-in 2.799 HRD-in -64.38, -48.85 71.21, 7.9 in-in-in SNCiii in-in ActLoopNT-in 3.005 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -128.79, 173.68 APE9-dihe-na 99.72, 167.49 APE8-dihe-in -63.26, 121.22 APE8-rot-in 308.35 APE67-dihe-in -44.49, -32.42 -49.46, -55.33 APE12-dist-in 10.321 APE11-dist-in 11.628 APE10-dist-in 6.241 APE9-dist-in 4.05 None None None XRAY 2.9 0.255 0.284 B 342 324 7 0 0 3 [[205, 494]] 1.0 1ias Homo sapiens TKL_TGFBR1_HUMAN TKL 4.9e-85 291.2 3 266 264 350 351 352 354 356 232 245 249 330 332 331 333 400 382 377 376 375 374 373 372 371 281 TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 1IASC P36897 171 500 503.0 No_ligand No_ligand Active DFGin 6.59 12.711 BLAminus -150.31, 164.7 71.4, 89.07 -106.94, 23.22 312.6, 1.77 -61.3, -25.67 in-in in 8.197 Saltbr-in 2.799 HRD-in -63.0, -50.37 71.83, 9.79 in-in-in SNCiii in-in ActLoopNT-in 3.013 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -119.75, 170.21 APE9-dihe-na 100.55, 167.25 APE8-dihe-in -63.65, 121.53 APE8-rot-in 308.64 APE67-dihe-in -44.33, -30.7 -49.24, -56.44 APE12-dist-in 11.349 APE11-dist-in 11.759 APE10-dist-in 6.222 APE9-dist-in 4.15 None None None XRAY 2.9 0.255 0.284 C 342 330 0 0 0 0 [[205, 494]] 1.0 1ias Homo sapiens TKL_TGFBR1_HUMAN TKL 4.9e-85 291.2 3 266 264 350 351 352 354 356 232 245 249 330 332 331 333 400 382 377 376 375 374 373 372 371 281 TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 1IASD P36897 171 500 503.0 No_ligand No_ligand Active DFGin 6.594 12.743 BLAminus -152.15, 165.79 70.83, 87.83 -105.27, 21.55 312.92, 0.98 -60.27, -25.54 in-in in 8.189 Saltbr-in 2.775 HRD-in -64.51, -48.18 71.39, 8.63 in-in-in SNCiii in-in ActLoopNT-in 2.993 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -131.69, 169.96 APE9-dihe-na 98.27, 166.26 APE8-dihe-in -61.5, 120.34 APE8-rot-in 308.37 APE67-dihe-in -44.16, -31.51 -48.36, -56.13 APE12-dist-in 10.732 APE11-dist-in 11.784 APE10-dist-in 6.18 APE9-dist-in 4.04 None None None XRAY 2.9 0.255 0.284 D 342 330 0 0 0 0 [[205, 494]] 1.0 1ias Homo sapiens TKL_TGFBR1_HUMAN TKL 4.9e-85 291.2 3 266 264 350 351 352 354 356 232 245 249 330 332 331 333 400 382 377 376 375 374 373 372 371 281 TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 1IASE P36897 171 500 503.0 No_ligand No_ligand Active DFGin 6.685 12.738 BLAminus -151.39, 165.15 70.82, 89.42 -106.94, 21.97 311.98, 2.05 -61.66, -24.41 in-in in 8.226 Saltbr-in 2.803 HRD-in -61.95, -50.33 72.19, 7.85 in-in-in SNCiii in-in ActLoopNT-in 3.008 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -127.31, 173.9 APE9-dihe-na 98.05, 167.39 APE8-dihe-in -64.1, 121.3 APE8-rot-in 308.19 APE67-dihe-in -45.93, -31.42 -49.14, -54.62 APE12-dist-in 11.636 APE11-dist-in 11.505 APE10-dist-in 6.149 APE9-dist-in 4.002 None None None XRAY 2.9 0.255 0.284 E 342 330 0 0 0 0 [[205, 494]] 1.0 1ias Homo sapiens TKL_TGFBR1_HUMAN TKL 4.9e-85 291.2 3 266 264 350 351 352 354 356 232 245 249 330 332 331 333 400 382 377 376 375 374 373 372 371 281 TGF-beta receptor type-1

PDB: 1IAS — TKL TGFR1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name