| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | TEK | TIE2_HUMAN | 1FVRA | Q02763 | 813 | 1121 | 1124.0 | No_ligand | No_ligand | Inactive | DFGinter | 8.4168 | 7.2594 | BABtrans | -70.32, 127.73 | -127.01, 36.72 | -94.99, 138.29 | 184.97, 79.8 | 67.05, 29.11 | out-out | out | 10.3727 | Saltbr-out | 7.4399 | HRD-in | -69.68, -50.63 | 81.63, -26.26 | out-out-out | SNCooo | out-out | ActLoopNT-out | 5.1165 | ActLoopCT-out | TYR | APEdihe_nniai | APEdist_aaao | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, 124.88 | APE8-dihe-in | -75.53, 55.91 | APE8-rot-na | 38.59 | APE67-dihe-in | -71.29, -9.41 | -46.42, -37.9 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-out | 8.5146 | None | None | None | XRAY | 2.2 | 0.195 | 0.225 | A | 327.0 | 299.0 | 10 | 27 | 23 | 4 | [[824, 1094]] | 1.0 | 1fvr | TYR_TEK_HUMAN | TYR | 8.3e-91 | 309.8 | 1.0 | 260.0 | 260.0 | 981 | 982 | 983 | 985 | 987 | 855 | 872 | 876 | 961 | 963 | 962 | 964.0 | 1020 | 1008 | 1003 | 1002 | 1001 | 1000 | 999 | 998 | 997 | 903 | Angiopoietin-1 receptor |
| TYR | TEK | TIE2_HUMAN | 1FVRB | Q02763 | 813 | 1121 | 1124.0 | No_ligand | No_ligand | Inactive | DFGinter | 8.5901 | 7.1844 | BABtrans | -71.55, 125.08 | -125.14, 43.48 | -101.19, 137.55 | 183.68, 81.8 | 68.42, 28.27 | out-out | out | 10.1008 | Saltbr-out | 7.6004 | HRD-in | -66.4, -52.26 | 80.81, -19.06 | out-out-out | SNCooo | out-out | ActLoopNT-out | 5.1313 | ActLoopCT-out | TYR | APEdihe_niiai | APEdist_aaao | APE10-dihe-none | 999.0, -27.62 | APE9-dihe-in | -107.96, 129.21 | APE8-dihe-in | -75.73, 57.96 | APE8-rot-na | 37.26 | APE67-dihe-in | -64.73, -13.95 | -46.88, -41.75 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 17.2607 | APE9-dist-out | 8.6429 | None | None | None | XRAY | 2.2 | 0.195 | 0.225 | B | 327.0 | 300.0 | 9 | 27 | 24 | 3 | [[824, 1094]] | 1.0 | 1fvr | TYR_TEK_HUMAN | TYR | 8.3e-91 | 309.8 | 1.0 | 260.0 | 260.0 | 981 | 982 | 983 | 985 | 987 | 855 | 872 | 876 | 961 | 963 | 962 | 964.0 | 1020 | 1008 | 1003 | 1002 | 1001 | 1000 | 999 | 998 | 997 | 903 | Angiopoietin-1 receptor |
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | TEK | TIE2_HUMAN | 1FVRA | Q02763 | 813 | 1121 | 1124.0 | No_ligand | No_ligand | Inactive | DFGinter | 8.4168 | 7.2594 | BABtrans | -70.32, 127.73 | -127.01, 36.72 | -94.99, 138.29 | 184.97, 79.8 | 67.05, 29.11 | out-out | out | 10.3727 | Saltbr-out | 7.4399 | HRD-in | -69.68, -50.63 | 81.63, -26.26 | out-out-out | SNCooo | out-out | ActLoopNT-out | 5.1165 | ActLoopCT-out | TYR | APEdihe_nniai | APEdist_aaao | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, 124.88 | APE8-dihe-in | -75.53, 55.91 | APE8-rot-na | 38.59 | APE67-dihe-in | -71.29, -9.41 | -46.42, -37.9 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-out | 8.5146 | None | None | None | XRAY | 2.2 | 0.195 | 0.225 | A | 327.0 | 299.0 | 10 | 27 | 23 | 4 | [[824, 1094]] | 1.0 | 1fvr | Homo sapiens | TYR_TEK_HUMAN | TYR | 8.3e-91 | 309.8 | 1.0 | 260.0 | 260.0 | 981 | 982 | 983 | 985 | 987 | 855 | 872 | 876 | 961 | 963 | 962 | 964.0 | 1020 | 1008 | 1003 | 1002 | 1001 | 1000 | 999 | 998 | 997 | 903 | Angiopoietin-1 receptor |
| TYR | TEK | TIE2_HUMAN | 1FVRB | Q02763 | 813 | 1121 | 1124.0 | No_ligand | No_ligand | Inactive | DFGinter | 8.5901 | 7.1844 | BABtrans | -71.55, 125.08 | -125.14, 43.48 | -101.19, 137.55 | 183.68, 81.8 | 68.42, 28.27 | out-out | out | 10.1008 | Saltbr-out | 7.6004 | HRD-in | -66.4, -52.26 | 80.81, -19.06 | out-out-out | SNCooo | out-out | ActLoopNT-out | 5.1313 | ActLoopCT-out | TYR | APEdihe_niiai | APEdist_aaao | APE10-dihe-none | 999.0, -27.62 | APE9-dihe-in | -107.96, 129.21 | APE8-dihe-in | -75.73, 57.96 | APE8-rot-na | 37.26 | APE67-dihe-in | -64.73, -13.95 | -46.88, -41.75 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 17.2607 | APE9-dist-out | 8.6429 | None | None | None | XRAY | 2.2 | 0.195 | 0.225 | B | 327.0 | 300.0 | 9 | 27 | 24 | 3 | [[824, 1094]] | 1.0 | 1fvr | Homo sapiens | TYR_TEK_HUMAN | TYR | 8.3e-91 | 309.8 | 1.0 | 260.0 | 260.0 | 981 | 982 | 983 | 985 | 987 | 855 | 872 | 876 | 961 | 963 | 962 | 964.0 | 1020 | 1008 | 1003 | 1002 | 1001 | 1000 | 999 | 998 | 997 | 903 | Angiopoietin-1 receptor |
| Spatial label | Dihedral label | Number of Chains | Percent | Representative |
|---|
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|