Ligand: ZSB (Zasocitinib)

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 3 100.0% 8S9AA
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR TYK2-1 TYK2_HUMAN 8S9AA 1.83 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao ZSB Type1 577 - 868 0 None None Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 8S9AB 1.83 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao ZSB Type1 578 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 8S9AC 1.83 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao ZSB Type1 578 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2

Ligand: ZSB (Zasocitinib)

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 3 100.0% 8S9AA
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR TYK2-1 TYK2_HUMAN 8S9AA 1.83 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao ZSB Type1 577 - 868 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-1 TYK2_HUMAN 8S9AB 1.83 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao ZSB Type1 578 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens
TYR TYK2-1 TYK2_HUMAN 8S9AC 1.83 Pseudo DFGin‑None in-na out-out TYR APEdihe_oooao APEdist_aaao ZSB Type1 578 - 867 0 None None Non-receptor tyrosine-protein kinase TYK2 Homo sapiens

Ligand: ZSB (Zasocitinib)

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Advanced page

Hover over column headers for tooltip help

Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism