Ligand: ZOV

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 7MX3A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL RIPK3 RIPK3_HUMAN 7MX3B Q9Y572 12 309 518.0 ZOV:401 Type1 Inactive DFGin 6.5416 14.2613 BLAminus -142.24, -163.59 59.46, 56.29 -87.14, 32.54 292.99, 86.32 -63.8, -63.45 in-out in 8.2134 Saltbr-out 3.8841 HRD-in -71.92, -42.98 73.44, -14.04 out-in-none SNCoin in-none ActLoopNT-in 2.9397 ActLoopCT-none nonTYR APEdihe_aanii APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 174.97 APE8-rot-in 306.5 APE67-dihe-in -71.82, -40.75 -58.31, -39.26 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 C3S,C110A None None XRAY 3.23 0.244 0.285 B 319.0 269.0 29 30 14 16 [[21, 285]] 1.0 7mx3 TKL_RIPK3_HUMAN TKL 7.4e-66 228.4 1.0 265.0 265.0 159 160 161 163 165 50 60 64 139 141 140 142.0 203 189 184 183 182 181 180 179 178 95 Receptor-interacting serine/threonine-protein kinase 3
TKL RIPK3 RIPK3_HUMAN 7MX3A Q9Y572 12 314 518.0 ZOV:401 Type1.5_Back None DFGin 6.2221 13.9088 BLAminus -152.35, -176.12 58.98, 65.68 -88.59, 21.74 285.92, 83.22 -75.2, -29.2 in-in in 7.9672 Saltbr-in 2.917 HRD-in -70.69, -48.21 67.95, 8.04 in-in-none SNCiin in-none ActLoopNT-in 3.2018 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none -69.66, -25.03 999.0, -33.0 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 C3S,C110A None None XRAY 3.23 0.244 0.285 A 319.0 292.0 11 30 20 10 [[21, 285]] 1.0 7mx3 TKL_RIPK3_HUMAN TKL 7.4e-66 228.4 1.0 265.0 265.0 159 160 161 163 165 50 60 64 139 141 140 142.0 203 189 184 183 182 181 180 179 178 95 Receptor-interacting serine/threonine-protein kinase 3
TKL RIPK3 RIPK3_HUMAN 7MX3C Q9Y572 9 311 518.0 ZOV:401 Type1.5_Back None DFGin 6.3242 14.4086 BLAminus -144.06, -179.33 56.59, 66.53 -89.63, 30.65 289.6, 92.66 -94.37, -38.42 in-in in 7.3677 Saltbr-in 3.19 HRD-in -62.63, -60.0 65.83, 13.04 in-in-none SNCiin in-none ActLoopNT-in 3.1544 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none -60.63, -27.61 999.0, -44.75 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 C3S,C110A None None XRAY 3.23 0.244 0.285 C 319.0 285.0 18 30 20 10 [[21, 285]] 1.0 7mx3 TKL_RIPK3_HUMAN TKL 7.4e-66 228.4 1.0 265.0 265.0 159 160 161 163 165 50 60 64 139 141 140 142.0 203 189 184 183 182 181 180 179 178 95 Receptor-interacting serine/threonine-protein kinase 3
TKL RIPK3 RIPK3_HUMAN 7MX3D Q9Y572 12 311 518.0 ZOV:401 Type1.5_Back None DFGin 6.1579 13.9338 BLAminus -152.67, -168.91 60.99, 69.08 -93.05, 21.87 286.54, 121.22 -73.96, -39.13 in-in in 8.1149 Saltbr-in 3.2288 HRD-in -81.46, -31.71 66.32, -56.05 in-in-none SNCiin in-none ActLoopNT-in 2.9385 ActLoopCT-none nonTYR APEdihe_aanii APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 153.09 APE8-rot-in 303.22 APE67-dihe-in -61.12, -38.55 -55.88, -51.2 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 C3S,C110A None None XRAY 3.23 0.244 0.285 D 319.0 280.0 19 30 16 14 [[21, 285]] 1.0 7mx3 TKL_RIPK3_HUMAN TKL 7.4e-66 228.4 1.0 265.0 265.0 159 160 161 163 165 50 60 64 139 141 140 142.0 203 189 184 183 182 181 180 179 178 95 Receptor-interacting serine/threonine-protein kinase 3

Ligand: ZOV

Total number of chains: 6
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 6 100.0% 7MX3A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL RIPK3 RIPK3_HUMAN 7MX3B Q9Y572 12 309 518.0 ZOV:401 Type1 Inactive DFGin 6.5416 14.2613 BLAminus -142.24, -163.59 59.46, 56.29 -87.14, 32.54 292.99, 86.32 -63.8, -63.45 in-out in 8.2134 Saltbr-out 3.8841 HRD-in -71.92, -42.98 73.44, -14.04 out-in-none SNCoin in-none ActLoopNT-in 2.9397 ActLoopCT-none nonTYR APEdihe_aanii APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 174.97 APE8-rot-in 306.5 APE67-dihe-in -71.82, -40.75 -58.31, -39.26 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 C3S,C110A None None XRAY 3.23 0.244 0.285 B 319.0 269.0 29 30 14 16 [[21, 285]] 1.0 7mx3 Homo sapiens TKL_RIPK3_HUMAN TKL 7.4e-66 228.4 1.0 265.0 265.0 159 160 161 163 165 50 60 64 139 141 140 142.0 203 189 184 183 182 181 180 179 178 95 Receptor-interacting serine/threonine-protein kinase 3
TKL RIPK3 RIPK3_HUMAN 7MX3A Q9Y572 12 314 518.0 ZOV:401 Type1.5_Back None DFGin 6.2221 13.9088 BLAminus -152.35, -176.12 58.98, 65.68 -88.59, 21.74 285.92, 83.22 -75.2, -29.2 in-in in 7.9672 Saltbr-in 2.917 HRD-in -70.69, -48.21 67.95, 8.04 in-in-none SNCiin in-none ActLoopNT-in 3.2018 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none -69.66, -25.03 999.0, -33.0 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 C3S,C110A None None XRAY 3.23 0.244 0.285 A 319.0 292.0 11 30 20 10 [[21, 285]] 1.0 7mx3 Homo sapiens TKL_RIPK3_HUMAN TKL 7.4e-66 228.4 1.0 265.0 265.0 159 160 161 163 165 50 60 64 139 141 140 142.0 203 189 184 183 182 181 180 179 178 95 Receptor-interacting serine/threonine-protein kinase 3
TKL RIPK3 RIPK3_HUMAN 7MX3C Q9Y572 9 311 518.0 ZOV:401 Type1.5_Back None DFGin 6.3242 14.4086 BLAminus -144.06, -179.33 56.59, 66.53 -89.63, 30.65 289.6, 92.66 -94.37, -38.42 in-in in 7.3677 Saltbr-in 3.19 HRD-in -62.63, -60.0 65.83, 13.04 in-in-none SNCiin in-none ActLoopNT-in 3.1544 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none -60.63, -27.61 999.0, -44.75 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 C3S,C110A None None XRAY 3.23 0.244 0.285 C 319.0 285.0 18 30 20 10 [[21, 285]] 1.0 7mx3 Homo sapiens TKL_RIPK3_HUMAN TKL 7.4e-66 228.4 1.0 265.0 265.0 159 160 161 163 165 50 60 64 139 141 140 142.0 203 189 184 183 182 181 180 179 178 95 Receptor-interacting serine/threonine-protein kinase 3
TKL RIPK3 RIPK3_HUMAN 7MX3D Q9Y572 12 311 518.0 ZOV:401 Type1.5_Back None DFGin 6.1579 13.9338 BLAminus -152.67, -168.91 60.99, 69.08 -93.05, 21.87 286.54, 121.22 -73.96, -39.13 in-in in 8.1149 Saltbr-in 3.2288 HRD-in -81.46, -31.71 66.32, -56.05 in-in-none SNCiin in-none ActLoopNT-in 2.9385 ActLoopCT-none nonTYR APEdihe_aanii APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 153.09 APE8-rot-in 303.22 APE67-dihe-in -61.12, -38.55 -55.88, -51.2 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 C3S,C110A None None XRAY 3.23 0.244 0.285 D 319.0 280.0 19 30 16 14 [[21, 285]] 1.0 7mx3 Homo sapiens TKL_RIPK3_HUMAN TKL 7.4e-66 228.4 1.0 265.0 265.0 159 160 161 163 165 50 60 64 139 141 140 142.0 203 189 184 183 182 181 180 179 178 95 Receptor-interacting serine/threonine-protein kinase 3
TKL RIPK3 RIPK3_MOUSE 9IWZA Q9QZL0 13 312 486.0 ZOV:401 Type1.5_Back None DFGin 6.1672 13.3322 BLAminus -140.79, 171.83 65.16, 90.29 -104.26, 18.26 298.04, 95.08 -65.53, -28.75 in-in in 7.87 Saltbr-in 2.8577 HRD-in -70.03, -51.19 78.93, -3.69 in-in-none SNCiin in-none ActLoopNT-in 2.7668 ActLoopCT-none nonTYR APEdihe_aaiii APEdist_nnii APE10-dihe-na 999.0, -29.88 APE9-dihe-na 105.08, -174.88 APE8-dihe-in -93.5, 124.97 APE8-rot-in 297.04 APE67-dihe-in -65.66, -19.22 -68.64, -29.74 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-in 7.3866 APE9-dist-in 5.623 None None None XRAY 1.82 0.178 0.211 A 325.0 285.0 15 34 19 15 [[20, 290]] 1.0 9iwz Mus musculus TKL_RIPK3_MOUSE TKL 5e-60 209.3 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
TKL RIPK3 RIPK3_MOUSE 9IWZB Q9QZL0 14 313 486.0 ZOV:401 Type1.5_Back Inactive DFGin 5.9966 13.3046 BLAminus -144.47, 173.55 62.65, 86.08 -102.43, 20.57 300.27, 99.76 -65.16, -25.91 in-in in 8.2133 Saltbr-in 2.6838 HRD-in -67.11, -51.33 74.52, -2.58 in-in-out SNCiio in-out ActLoopNT-in 2.8492 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnoo APE10-dihe-na 999.0, 2.11 APE9-dihe-na -92.49, -170.4 APE8-dihe-in -66.48, 151.74 APE8-rot-out 179.71 APE67-dihe-in -61.05, -23.54 -107.82, 2.35 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 11.5094 APE9-dist-out 9.9204 None None None XRAY 1.82 0.178 0.211 B 325.0 271.0 29 34 18 16 [[20, 290]] 1.0 9iwz Mus musculus TKL_RIPK3_MOUSE TKL 5e-60 209.3 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3

Ligand: ZOV

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 9IWZA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL RIPK3 RIPK3_MOUSE 9IWZA Q9QZL0 13 312 486.0 ZOV:401 Type1.5_Back None DFGin 6.1672 13.3322 BLAminus -140.79, 171.83 65.16, 90.29 -104.26, 18.26 298.04, 95.08 -65.53, -28.75 in-in in 7.87 Saltbr-in 2.8577 HRD-in -70.03, -51.19 78.93, -3.69 in-in-none SNCiin in-none ActLoopNT-in 2.7668 ActLoopCT-none nonTYR APEdihe_aaiii APEdist_nnii APE10-dihe-na 999.0, -29.88 APE9-dihe-na 105.08, -174.88 APE8-dihe-in -93.5, 124.97 APE8-rot-in 297.04 APE67-dihe-in -65.66, -19.22 -68.64, -29.74 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-in 7.3866 APE9-dist-in 5.623 None None None XRAY 1.82 0.178 0.211 A 325.0 285.0 15 34 19 15 [[20, 290]] 1.0 9iwz Mus musculus TKL_RIPK3_MOUSE TKL 5e-60 209.3 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3
TKL RIPK3 RIPK3_MOUSE 9IWZB Q9QZL0 14 313 486.0 ZOV:401 Type1.5_Back Inactive DFGin 5.9966 13.3046 BLAminus -144.47, 173.55 62.65, 86.08 -102.43, 20.57 300.27, 99.76 -65.16, -25.91 in-in in 8.2133 Saltbr-in 2.6838 HRD-in -67.11, -51.33 74.52, -2.58 in-in-out SNCiio in-out ActLoopNT-in 2.8492 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnoo APE10-dihe-na 999.0, 2.11 APE9-dihe-na -92.49, -170.4 APE8-dihe-in -66.48, 151.74 APE8-rot-out 179.71 APE67-dihe-in -61.05, -23.54 -107.82, 2.35 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 11.5094 APE9-dist-out 9.9204 None None None XRAY 1.82 0.178 0.211 B 325.0 271.0 29 34 18 16 [[20, 290]] 1.0 9iwz Mus musculus TKL_RIPK3_MOUSE TKL 5e-60 209.3 3.0 265.0 263.0 160 161 162 164 166 51 61 65 140 142 141 143.0 208 194 189 188 187 186 185 184 183 96 Receptor-interacting serine/threonine-protein kinase 3