Ligand: YUN

Total number of chains: 7
Active chains: 5
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 5 71.4% 4LRMA
DFGin ABAminus 2 28.6% 4LL0A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR EGFR EGFR_HUMAN 4LL0A 4.0 Inactive DFGin‑ABAminus in-out in-none TYR APEdihe_nniai APEdist_aaai YUN Type1 697 - 1017 0 None T790M,L858R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4LL0B 4.0 Inactive DFGin‑ABAminus in-out in-none TYR APEdihe_nniai APEdist_aaai YUN Type1 698 - 1017 0 None T790M,L858R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4LRMA 3.526 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai YUN Type1 696 - 999 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4LRMB 3.526 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai YUN Type1 695 - 984 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4LRMC 3.526 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai YUN Type1 694 - 983 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4LRMD 3.526 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai YUN Type1 696 - 981 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4LRME 3.526 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai YUN Type1 697 - 983 0 None None Epidermal growth factor receptor

Ligand: YUN

Total number of chains: 7
Active chains: 5
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 5 71.4% 4LRMA
DFGin ABAminus 2 28.6% 4LL0A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR EGFR EGFR_HUMAN 4LL0A 4.0 Inactive DFGin‑ABAminus in-out in-none TYR APEdihe_nniai APEdist_aaai YUN Type1 697 - 1017 0 None T790M,L858R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 4LL0B 4.0 Inactive DFGin‑ABAminus in-out in-none TYR APEdihe_nniai APEdist_aaai YUN Type1 698 - 1017 0 None T790M,L858R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 4LRMA 3.526 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai YUN Type1 696 - 999 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 4LRMB 3.526 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai YUN Type1 695 - 984 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 4LRMC 3.526 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai YUN Type1 694 - 983 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 4LRMD 3.526 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai YUN Type1 696 - 981 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 4LRME 3.526 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai YUN Type1 697 - 983 0 None None Epidermal growth factor receptor Homo sapiens

Ligand: YUN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism