Ligand: X2M (Semaxanib)

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 2X2MA
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR RET RET_HUMAN 2X2MA 2.5 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai X2M Type1 703 - 1013 0 PTR905 None Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN 2X2MB 2.5 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai X2M Type1 703 - 1011 0 PTR905 None Proto-oncogene tyrosine-protein kinase receptor Ret

Ligand: X2M (Semaxanib)

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 2X2MA
All chains - renumbered by
Uniprot PDB Alignment
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Hover over column headers for tooltip help

Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR RET RET_HUMAN 2X2MA 2.5 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai X2M Type1 703 - 1013 0 PTR905 None Proto-oncogene tyrosine-protein kinase receptor Ret Homo sapiens
TYR RET RET_HUMAN 2X2MB 2.5 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai X2M Type1 703 - 1011 0 PTR905 None Proto-oncogene tyrosine-protein kinase receptor Ret Homo sapiens

Ligand: X2M (Semaxanib)

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Advanced page

Hover over column headers for tooltip help

Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism