Ligand: X2M (Semaxanib)

Total number of chains: 2
Spatial label Dihedral label Number of Chains Representative
DFGin BLAminus 2 2X2MA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR RET RET_HUMAN 2X2MA 2.5 Inactive DFGin‑BLAminus in-in in-out X2M Type1 703 - 1013 0 X905 None Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN 2X2MB 2.5 Inactive DFGin‑BLAminus in-in in-out X2M Type1 703 - 1011 0 X905 None Proto-oncogene tyrosine-protein kinase receptor Ret

Ligand: X2M (Semaxanib)

Total number of chains: 2
Spatial label Dihedral label Number of Chains Representative
DFGin BLAminus 2 2X2MA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR RET RET_HUMAN 2X2MA 2.5 Inactive DFGin‑BLAminus in-in in-out X2M Type1 703 - 1013 0 X905 None Proto-oncogene tyrosine-protein kinase receptor Ret Homo sapiens
TYR RET RET_HUMAN 2X2MB 2.5 Inactive DFGin‑BLAminus in-in in-out X2M Type1 703 - 1011 0 X905 None Proto-oncogene tyrosine-protein kinase receptor Ret Homo sapiens

Ligand: X2M (Semaxanib)

Total number of chains: 0
Spatial label Dihedral label Number of Chains Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism