Ligand: X11

Total number of chains: 2
Active chains: 1
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 4QNAA
None None 1 50.0% 3QQJA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 3QQJA P24941 1 298 298.0 X11:300 Type1 Inactive None 11.2957 17.1399 None -118.58, 158.94 68.7, 32.83 -72.06, 149.44 252.09, 99.03 65.67, 11.61 out-out out 15.494 Saltbr-out 15.1854 HRD-in -89.76, -64.75 84.08, -16.02 out-out-out SNCooo out-out ActLoopNT-out 5.7229 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oooo APE10-dihe-na -51.86, 104.06 APE9-dihe-na -56.13, 139.44 APE8-dihe-in -84.97, 113.86 APE8-rot-in 306.15 APE67-dihe-in -54.47, -25.16 -98.88, -9.11 APE12-dist-out 20.9882 APE11-dist-out 17.1911 APE10-dist-out 20.0939 APE9-dist-out 11.2335 None None None XRAY 1.7 0.206 0.237 A 306.0 294.0 4 28 28 0 [[4, 286]] 1.0 3qqj CMGC_CDK2_HUMAN CMGC 7e-90 307.7 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
STE STK24 STK24_HUMAN 4QNAA Q9Y6E0 27 311 443.0 X11:60401 Type1 Active DFGin 6.7293 14.851 BLAminus -130.1, 169.64 67.98, 80.07 -98.12, 24.56 287.17, 78.82 -61.05, -22.93 in-in in 8.7716 Saltbr-in 2.6835 HRD-in -70.07, -51.25 75.01, 0.43 in-in-in SNCiii in-in ActLoopNT-in 2.7727 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -135.0, 160.27 APE9-dihe-na 130.05, -167.15 APE8-dihe-in -116.99, 118.73 APE8-rot-in 306.87 APE67-dihe-in -55.73, -29.17 -44.29, -48.73 APE12-dist-in 8.2625 APE11-dist-in 10.9208 APE10-dist-in 5.1037 APE9-dist-in 3.3454 None TPO190 TPO190 XRAY 1.849 0.18 0.215 A 310.0 285.0 0 28 28 0 [[36, 286]] 1.0 4qna STE_STK24_HUMAN STE 3.9e-100 340.4 1.0 257.0 257.0 173 174 175 177 179 65 82 86 153 155 154 156.0 213 201 196 195 194 193 192 191 190 112 Serine/threonine-protein kinase 24

Ligand: X11

Total number of chains: 2
Active chains: 1
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 4QNAA
None None 1 50.0% 3QQJA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 3QQJA P24941 1 298 298.0 X11:300 Type1 Inactive None 11.2957 17.1399 None -118.58, 158.94 68.7, 32.83 -72.06, 149.44 252.09, 99.03 65.67, 11.61 out-out out 15.494 Saltbr-out 15.1854 HRD-in -89.76, -64.75 84.08, -16.02 out-out-out SNCooo out-out ActLoopNT-out 5.7229 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oooo APE10-dihe-na -51.86, 104.06 APE9-dihe-na -56.13, 139.44 APE8-dihe-in -84.97, 113.86 APE8-rot-in 306.15 APE67-dihe-in -54.47, -25.16 -98.88, -9.11 APE12-dist-out 20.9882 APE11-dist-out 17.1911 APE10-dist-out 20.0939 APE9-dist-out 11.2335 None None None XRAY 1.7 0.206 0.237 A 306.0 294.0 4 28 28 0 [[4, 286]] 1.0 3qqj Homo sapiens CMGC_CDK2_HUMAN CMGC 7e-90 307.7 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
STE STK24 STK24_HUMAN 4QNAA Q9Y6E0 27 311 443.0 X11:60401 Type1 Active DFGin 6.7293 14.851 BLAminus -130.1, 169.64 67.98, 80.07 -98.12, 24.56 287.17, 78.82 -61.05, -22.93 in-in in 8.7716 Saltbr-in 2.6835 HRD-in -70.07, -51.25 75.01, 0.43 in-in-in SNCiii in-in ActLoopNT-in 2.7727 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -135.0, 160.27 APE9-dihe-na 130.05, -167.15 APE8-dihe-in -116.99, 118.73 APE8-rot-in 306.87 APE67-dihe-in -55.73, -29.17 -44.29, -48.73 APE12-dist-in 8.2625 APE11-dist-in 10.9208 APE10-dist-in 5.1037 APE9-dist-in 3.3454 None TPO190 TPO190 XRAY 1.849 0.18 0.215 A 310.0 285.0 0 28 28 0 [[36, 286]] 1.0 4qna Homo sapiens STE_STK24_HUMAN STE 3.9e-100 340.4 1.0 257.0 257.0 173 174 175 177 179 65 82 86 153 155 154 156.0 213 201 196 195 194 193 192 191 190 112 Serine/threonine-protein kinase 24

Ligand: X11

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name