Ligand: X11

Total number of chains: 2
Active chains: 1
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 4QNAA
None None 1 50.0% 3QQJA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CMGC CDK2 CDK2_HUMAN 3QQJA 1.7 Inactive None‑None out-out out-out nonTYR APEdihe_aaiii APEdist_oooo X11 Type1 1 - 298 0 None None Cyclin-dependent kinase 2
STE STK24 STK24_HUMAN 4QNAA 1.849 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii X11 Type1 27 - 311 0 TPO190 None Serine/threonine-protein kinase 24

Ligand: X11

Total number of chains: 2
Active chains: 1
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 4QNAA
None None 1 50.0% 3QQJA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC CDK2 CDK2_HUMAN 3QQJA 1.7 Inactive None‑None out-out out-out nonTYR APEdihe_aaiii APEdist_oooo X11 Type1 1 - 298 0 None None Cyclin-dependent kinase 2 Homo sapiens
STE STK24 STK24_HUMAN 4QNAA 1.849 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii X11 Type1 27 - 311 0 TPO190 None Serine/threonine-protein kinase 24 Homo sapiens

Ligand: X11

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism