Ligand: WHQ

Total number of chains: 1
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 1 100.0% 8VNXA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK10 MK10_HUMAN 8VNXA P53779 45 400 464.0 WHQ:501 Type1 Inactive DFGin 3.9407 14.5074 ABAminus -102.24, -9.11 -136.18, 172.0 -118.53, 8.8 298.29, 96.77 92.72, -156.21 out-out out 10.4708 Saltbr-out 5.0821 HRD-in -72.08, -64.12 78.01, -7.94 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oooo APE10-dihe-na -140.26, 141.98 APE9-dihe-na -90.13, 137.7 APE8-dihe-in -85.91, 121.26 APE8-rot-in 296.57 APE67-dihe-in -68.08, -16.86 -115.62, -1.33 APE12-dist-out 20.9651 APE11-dist-out 15.3649 APE10-dist-out 16.042 APE9-dist-out 11.3616 None None None XRAY 2.0 0.214 0.256 A 464.0 346.0 5 27 22 5 [[64, 359]] 1.0 8vnx CMGC_MAPK10_HUMAN CMGC 3e-85 292.1 1.0 301.0 301.0 206 207 208 210 212 93 111 115 186 188 187 189.0 245 233 228 227 226 225 224 223 222 147 Mitogen-activated protein kinase 10

Ligand: WHQ

Total number of chains: 3
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 2 66.7% 8EFJA
DFGin ABAminus 1 33.3% 8VNXA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK10 MK10_HUMAN 8VNXA P53779 45 400 464.0 WHQ:501 Type1 Inactive DFGin 3.9407 14.5074 ABAminus -102.24, -9.11 -136.18, 172.0 -118.53, 8.8 298.29, 96.77 92.72, -156.21 out-out out 10.4708 Saltbr-out 5.0821 HRD-in -72.08, -64.12 78.01, -7.94 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oooo APE10-dihe-na -140.26, 141.98 APE9-dihe-na -90.13, 137.7 APE8-dihe-in -85.91, 121.26 APE8-rot-in 296.57 APE67-dihe-in -68.08, -16.86 -115.62, -1.33 APE12-dist-out 20.9651 APE11-dist-out 15.3649 APE10-dist-out 16.042 APE9-dist-out 11.3616 None None None XRAY 2.0 0.214 0.256 A 464.0 346.0 5 27 22 5 [[64, 359]] 1.0 8vnx Homo sapiens CMGC_MAPK10_HUMAN CMGC 3e-85 292.1 1.0 301.0 301.0 206 207 208 210 212 93 111 115 186 188 187 189.0 245 233 228 227 226 225 224 223 222 147 Mitogen-activated protein kinase 10
CMGC MAPK14 MK14_MOUSE 8EFJA P47811 5 360 360.0 WHQ:503 Type1 Inactive DFGin 6.6842 15.1508 None -107.83, -138.53 -47.2, 131.52 -82.89, 153.62 283.8, 59.38 -72.43, 123.55 in-in in 9.147 Saltbr-in 2.8713 HRD-in -63.56, -52.6 86.58, -8.43 in-out-out SNCioo out-out ActLoopNT-out 9.1047 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnoo APE10-dihe-na 999.0, -48.45 APE9-dihe-na -142.16, 106.07 APE8-dihe-in -57.79, 138.19 APE8-rot-out 182.41 APE67-dihe-in -58.85, -41.56 -95.36, -2.52 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 13.8627 APE9-dist-out 9.537 None None None XRAY 2.31 0.193 0.223 A 367.0 348.0 8 25 17 8 [[24, 308]] 1.0 8efj Mus musculus CMGC_MAPK14_MOUSE CMGC 2.1e-85 292.7 1.0 301.0 301.0 167 168 169 171 173 53 71 75 147 149 148 150.0 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_MOUSE 8VT6A P47811 5 360 360.0 WHQ:503 Type1 Inactive DFGin 6.7293 15.1507 None -106.7, -137.28 -49.07, 131.85 -82.77, 153.72 284.07, 57.8 -72.41, 123.53 in-in in 9.1741 Saltbr-in 2.5587 HRD-in -64.24, -49.87 82.02, -7.33 in-out-out SNCioo out-out ActLoopNT-out 9.1157 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnoo APE10-dihe-na 999.0, -58.08 APE9-dihe-na -131.51, 108.06 APE8-dihe-in -61.02, 149.49 APE8-rot-out 183.06 APE67-dihe-in -60.32, -29.4 -95.05, -11.94 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 13.7558 APE9-dist-out 9.4982 None None None XRAY 2.31 0.166 0.216 A 367.0 348.0 8 25 17 8 [[24, 308]] 1.0 8vt6 Mus musculus CMGC_MAPK14_MOUSE CMGC 2.1e-85 292.7 1.0 301.0 301.0 167 168 169 171 173 53 71 75 147 149 148 150.0 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14

Ligand: WHQ

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 2 100.0% 8EFJA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK14 MK14_MOUSE 8EFJA P47811 5 360 360.0 WHQ:503 Type1 Inactive DFGin 6.6842 15.1508 None -107.83, -138.53 -47.2, 131.52 -82.89, 153.62 283.8, 59.38 -72.43, 123.55 in-in in 9.147 Saltbr-in 2.8713 HRD-in -63.56, -52.6 86.58, -8.43 in-out-out SNCioo out-out ActLoopNT-out 9.1047 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnoo APE10-dihe-na 999.0, -48.45 APE9-dihe-na -142.16, 106.07 APE8-dihe-in -57.79, 138.19 APE8-rot-out 182.41 APE67-dihe-in -58.85, -41.56 -95.36, -2.52 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 13.8627 APE9-dist-out 9.537 None None None XRAY 2.31 0.193 0.223 A 367.0 348.0 8 25 17 8 [[24, 308]] 1.0 8efj Mus musculus CMGC_MAPK14_MOUSE CMGC 2.1e-85 292.7 1.0 301.0 301.0 167 168 169 171 173 53 71 75 147 149 148 150.0 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_MOUSE 8VT6A P47811 5 360 360.0 WHQ:503 Type1 Inactive DFGin 6.7293 15.1507 None -106.7, -137.28 -49.07, 131.85 -82.77, 153.72 284.07, 57.8 -72.41, 123.53 in-in in 9.1741 Saltbr-in 2.5587 HRD-in -64.24, -49.87 82.02, -7.33 in-out-out SNCioo out-out ActLoopNT-out 9.1157 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnoo APE10-dihe-na 999.0, -58.08 APE9-dihe-na -131.51, 108.06 APE8-dihe-in -61.02, 149.49 APE8-rot-out 183.06 APE67-dihe-in -60.32, -29.4 -95.05, -11.94 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 13.7558 APE9-dist-out 9.4982 None None None XRAY 2.31 0.166 0.216 A 367.0 348.0 8 25 17 8 [[24, 308]] 1.0 8vt6 Mus musculus CMGC_MAPK14_MOUSE CMGC 2.1e-85 292.7 1.0 301.0 301.0 167 168 169 171 173 53 71 75 147 149 148 150.0 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14