Ligand: W49

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 2 100.0% 8OUUB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR MET MET_HUMAN 8OUUA P08581 1059 1346 1390.0 W49:1404 Type3 Inactive DFGout 13.5148 6.8764 BBAminus -147.46, -168.73 -151.04, 108.81 -112.08, 40.61 288.5, 94.51 -110.14, -161.37 out-out out 12.355 Saltbr-out 10.4597 HRD-in -63.12, -55.99 76.4, -17.82 out-out-in SNCooi out-in ActLoopNT-out 9.0906 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -82.11, 150.07 APE9-dihe-in -72.2, 149.25 APE8-dihe-in -80.89, 58.5 APE8-rot-na 27.43 APE67-dihe-in -74.53, -1.63 -44.12, -49.33 APE12-dist-na 999.0 APE11-dist-na 6.5459 APE10-dist-na 10.7918 APE9-dist-in 7.8925 D1228V None None XRAY 1.77 0.203 0.225 A 309.0 284.0 4 32 28 4 [[1078, 1339]] 1.0 8ouu TYR_MET_HUMAN TYR 1.5e-91 312.8 2.0 260.0 259.0 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204.0 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8OUUB P08581 1057 1346 1390.0 W49:1405 Type3 Inactive DFGout 13.4883 6.9703 BBAminus -144.89, -171.19 -149.83, 102.26 -101.8, 30.99 273.18, 101.18 -108.36, -152.3 out-out out 12.3114 Saltbr-out 10.3828 HRD-in -62.48, -51.05 73.17, -16.23 out-out-out SNCooo out-out ActLoopNT-out 9.1882 ActLoopCT-out TYR APEdihe_iiiai APEdist_aaao APE10-dihe-in -63.11, 139.96 APE9-dihe-in -71.28, 138.06 APE8-dihe-in -78.82, 59.01 APE8-rot-na 36.37 APE67-dihe-in -74.44, -3.9 -45.73, -43.18 APE12-dist-na 10.6344 APE11-dist-na 6.5598 APE10-dist-na 11.6102 APE9-dist-out 8.2349 D1228V None None XRAY 1.77 0.203 0.225 B 309.0 290.0 0 32 32 0 [[1078, 1339]] 1.0 8ouu TYR_MET_HUMAN TYR 1.5e-91 312.8 2.0 260.0 259.0 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204.0 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor

Ligand: W49

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 2 100.0% 8OUUB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR MET MET_HUMAN 8OUUA P08581 1059 1346 1390.0 W49:1404 Type3 Inactive DFGout 13.5148 6.8764 BBAminus -147.46, -168.73 -151.04, 108.81 -112.08, 40.61 288.5, 94.51 -110.14, -161.37 out-out out 12.355 Saltbr-out 10.4597 HRD-in -63.12, -55.99 76.4, -17.82 out-out-in SNCooi out-in ActLoopNT-out 9.0906 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -82.11, 150.07 APE9-dihe-in -72.2, 149.25 APE8-dihe-in -80.89, 58.5 APE8-rot-na 27.43 APE67-dihe-in -74.53, -1.63 -44.12, -49.33 APE12-dist-na 999.0 APE11-dist-na 6.5459 APE10-dist-na 10.7918 APE9-dist-in 7.8925 D1228V None None XRAY 1.77 0.203 0.225 A 309.0 284.0 4 32 28 4 [[1078, 1339]] 1.0 8ouu Homo sapiens TYR_MET_HUMAN TYR 1.5e-91 312.8 2.0 260.0 259.0 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204.0 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8OUUB P08581 1057 1346 1390.0 W49:1405 Type3 Inactive DFGout 13.4883 6.9703 BBAminus -144.89, -171.19 -149.83, 102.26 -101.8, 30.99 273.18, 101.18 -108.36, -152.3 out-out out 12.3114 Saltbr-out 10.3828 HRD-in -62.48, -51.05 73.17, -16.23 out-out-out SNCooo out-out ActLoopNT-out 9.1882 ActLoopCT-out TYR APEdihe_iiiai APEdist_aaao APE10-dihe-in -63.11, 139.96 APE9-dihe-in -71.28, 138.06 APE8-dihe-in -78.82, 59.01 APE8-rot-na 36.37 APE67-dihe-in -74.44, -3.9 -45.73, -43.18 APE12-dist-na 10.6344 APE11-dist-na 6.5598 APE10-dist-na 11.6102 APE9-dist-out 8.2349 D1228V None None XRAY 1.77 0.203 0.225 B 309.0 290.0 0 32 32 0 [[1078, 1339]] 1.0 8ouu Homo sapiens TYR_MET_HUMAN TYR 1.5e-91 312.8 2.0 260.0 259.0 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204.0 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor

Ligand: W49

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name