| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | MET | MET_HUMAN | 8OWGA | P08581 | 1060 | 1344 | 1390.0 | W40:1401 | Type3 | Inactive | DFGout | 15.2151 | 7.185 | BBAminus | -151.69, 176.81 | -129.27, 111.57 | -101.99, 63.08 | 247.0, 19.93 | 135.49, 100.91 | out-none | out | 12.5638 | Saltbr-none | 999.0 | HRD-in | -54.29, -59.14 | 87.34, -18.08 | none-out-none | SNCnon | out-none | ActLoopNT-out | 6.4552 | ActLoopCT-none | TYR | APEdihe_nnnai | APEdist_aaan | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, 999.0 | APE8-dihe-none | 999.0, 39.54 | APE8-rot-na | 32.71 | APE67-dihe-in | -69.3, -0.31 | -58.16, -36.16 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-none | 999.0 | D1228V | None | None | XRAY | 2.631 | 0.283 | 0.329 | A | 309.0 | 244.0 | 41 | 32 | 15 | 17 | [[1078, 1339]] | 1.0 | 8owg | TYR_MET_HUMAN | TYR | 1.5e-91 | 312.8 | 2.0 | 260.0 | 259.0 | 1221 | 1222 | 1223 | 1225 | 1227 | 1110 | 1127 | 1131 | 1201 | 1203 | 1202 | 1204.0 | 1265 | 1253 | 1248 | 1247 | 1246 | 1245 | 1244 | 1243 | 1242 | 1158 | Hepatocyte growth factor receptor |
| TYR | MET | MET_HUMAN | 8OWGB | P08581 | 1060 | 1343 | 1390.0 | W40:1401 | Type3 | Inactive | DFGout | 13.4737 | 7.0272 | BBAminus | -143.52, -173.91 | -145.15, 96.11 | -104.84, 19.11 | 287.04, 87.7 | -144.89, 36.92 | out-none | out | 12.676 | Saltbr-none | 999.0 | HRD-in | -57.0, -54.53 | 71.26, 2.24 | none-out-in | SNCnoi | out-in | ActLoopNT-out | 8.8028 | ActLoopCT-in | TYR | APEdihe_iiiai | APEdist_aaai | APE10-dihe-in | -80.21, 155.54 | APE9-dihe-in | -138.84, 156.19 | APE8-dihe-in | -90.42, 73.4 | APE8-rot-na | 26.27 | APE67-dihe-in | -74.77, 0.81 | -53.95, -37.48 | APE12-dist-na | 13.9686 | APE11-dist-na | 10.9335 | APE10-dist-na | 9.9331 | APE9-dist-in | 7.2831 | D1228V | None | None | XRAY | 2.631 | 0.283 | 0.329 | B | 309.0 | 246.0 | 38 | 32 | 18 | 14 | [[1078, 1339]] | 1.0 | 8owg | TYR_MET_HUMAN | TYR | 1.5e-91 | 312.8 | 2.0 | 260.0 | 259.0 | 1221 | 1222 | 1223 | 1225 | 1227 | 1110 | 1127 | 1131 | 1201 | 1203 | 1202 | 1204.0 | 1265 | 1253 | 1248 | 1247 | 1246 | 1245 | 1244 | 1243 | 1242 | 1158 | Hepatocyte growth factor receptor |
| TYR | MET | MET_HUMAN | 8OWGC | P08581 | 1060 | 1343 | 1390.0 | W40:1401 | Type3 | Inactive | DFGout | 13.4942 | 7.3962 | BBAminus | -137.63, 176.74 | -129.85, 94.81 | -103.25, 51.6 | 272.59, 87.18 | 162.66, 999.0 | out-none | out | 12.7189 | Saltbr-none | 999.0 | HRD-in | -60.14, -44.34 | 69.98, -16.33 | none-none-out | SNCnno | none-out | ActLoopNT-none | 999.0 | ActLoopCT-out | TYR | APEdihe_nniai | APEdist_aaao | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, 120.95 | APE8-dihe-in | -84.26, 62.47 | APE8-rot-na | 30.42 | APE67-dihe-in | -68.37, 4.72 | -58.51, -48.0 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-out | 8.1323 | D1228V | None | None | XRAY | 2.631 | 0.283 | 0.329 | C | 309.0 | 235.0 | 49 | 32 | 12 | 20 | [[1078, 1339]] | 1.0 | 8owg | TYR_MET_HUMAN | TYR | 1.5e-91 | 312.8 | 2.0 | 260.0 | 259.0 | 1221 | 1222 | 1223 | 1225 | 1227 | 1110 | 1127 | 1131 | 1201 | 1203 | 1202 | 1204.0 | 1265 | 1253 | 1248 | 1247 | 1246 | 1245 | 1244 | 1243 | 1242 | 1158 | Hepatocyte growth factor receptor |
| TYR | MET | MET_HUMAN | 8OW3A | P08581 | 1058 | 1345 | 1390.0 | W40:1401 | Type3 | Inactive | DFGout | 13.2821 | 6.9493 | BBAminus | -144.85, -172.89 | -148.19, 116.28 | -124.16, 31.55 | 280.56, 89.39 | -106.2, 999.0 | out-none | out | 12.6628 | Saltbr-none | 999.0 | HRD-in | -58.32, -54.99 | 72.45, -5.24 | none-none-none | SNCnnn | none-none | ActLoopNT-none | 999.0 | ActLoopCT-none | TYR | APEdihe_nniai | APEdist_aaai | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, 130.74 | APE8-dihe-in | -87.02, 65.42 | APE8-rot-na | 27.11 | APE67-dihe-in | -76.81, 1.52 | -53.65, -34.46 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-in | 7.7431 | None | None | None | XRAY | 2.27 | 0.247 | 0.295 | A | 309.0 | 258.0 | 30 | 32 | 12 | 20 | [[1078, 1339]] | 1.0 | 8ow3 | TYR_MET_HUMAN | TYR | 6.9e-92 | 313.9 | 2.0 | 260.0 | 259.0 | 1221 | 1222 | 1223 | 1225 | 1227 | 1110 | 1127 | 1131 | 1201 | 1203 | 1202 | 1204.0 | 1265 | 1253 | 1248 | 1247 | 1246 | 1245 | 1244 | 1243 | 1242 | 1158 | Hepatocyte growth factor receptor |
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | MET | MET_HUMAN | 8OWGA | P08581 | 1060 | 1344 | 1390.0 | W40:1401 | Type3 | Inactive | DFGout | 15.2151 | 7.185 | BBAminus | -151.69, 176.81 | -129.27, 111.57 | -101.99, 63.08 | 247.0, 19.93 | 135.49, 100.91 | out-none | out | 12.5638 | Saltbr-none | 999.0 | HRD-in | -54.29, -59.14 | 87.34, -18.08 | none-out-none | SNCnon | out-none | ActLoopNT-out | 6.4552 | ActLoopCT-none | TYR | APEdihe_nnnai | APEdist_aaan | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, 999.0 | APE8-dihe-none | 999.0, 39.54 | APE8-rot-na | 32.71 | APE67-dihe-in | -69.3, -0.31 | -58.16, -36.16 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-none | 999.0 | D1228V | None | None | XRAY | 2.631 | 0.283 | 0.329 | A | 309.0 | 244.0 | 41 | 32 | 15 | 17 | [[1078, 1339]] | 1.0 | 8owg | Homo sapiens | TYR_MET_HUMAN | TYR | 1.5e-91 | 312.8 | 2.0 | 260.0 | 259.0 | 1221 | 1222 | 1223 | 1225 | 1227 | 1110 | 1127 | 1131 | 1201 | 1203 | 1202 | 1204.0 | 1265 | 1253 | 1248 | 1247 | 1246 | 1245 | 1244 | 1243 | 1242 | 1158 | Hepatocyte growth factor receptor |
| TYR | MET | MET_HUMAN | 8OWGB | P08581 | 1060 | 1343 | 1390.0 | W40:1401 | Type3 | Inactive | DFGout | 13.4737 | 7.0272 | BBAminus | -143.52, -173.91 | -145.15, 96.11 | -104.84, 19.11 | 287.04, 87.7 | -144.89, 36.92 | out-none | out | 12.676 | Saltbr-none | 999.0 | HRD-in | -57.0, -54.53 | 71.26, 2.24 | none-out-in | SNCnoi | out-in | ActLoopNT-out | 8.8028 | ActLoopCT-in | TYR | APEdihe_iiiai | APEdist_aaai | APE10-dihe-in | -80.21, 155.54 | APE9-dihe-in | -138.84, 156.19 | APE8-dihe-in | -90.42, 73.4 | APE8-rot-na | 26.27 | APE67-dihe-in | -74.77, 0.81 | -53.95, -37.48 | APE12-dist-na | 13.9686 | APE11-dist-na | 10.9335 | APE10-dist-na | 9.9331 | APE9-dist-in | 7.2831 | D1228V | None | None | XRAY | 2.631 | 0.283 | 0.329 | B | 309.0 | 246.0 | 38 | 32 | 18 | 14 | [[1078, 1339]] | 1.0 | 8owg | Homo sapiens | TYR_MET_HUMAN | TYR | 1.5e-91 | 312.8 | 2.0 | 260.0 | 259.0 | 1221 | 1222 | 1223 | 1225 | 1227 | 1110 | 1127 | 1131 | 1201 | 1203 | 1202 | 1204.0 | 1265 | 1253 | 1248 | 1247 | 1246 | 1245 | 1244 | 1243 | 1242 | 1158 | Hepatocyte growth factor receptor |
| TYR | MET | MET_HUMAN | 8OWGC | P08581 | 1060 | 1343 | 1390.0 | W40:1401 | Type3 | Inactive | DFGout | 13.4942 | 7.3962 | BBAminus | -137.63, 176.74 | -129.85, 94.81 | -103.25, 51.6 | 272.59, 87.18 | 162.66, 999.0 | out-none | out | 12.7189 | Saltbr-none | 999.0 | HRD-in | -60.14, -44.34 | 69.98, -16.33 | none-none-out | SNCnno | none-out | ActLoopNT-none | 999.0 | ActLoopCT-out | TYR | APEdihe_nniai | APEdist_aaao | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, 120.95 | APE8-dihe-in | -84.26, 62.47 | APE8-rot-na | 30.42 | APE67-dihe-in | -68.37, 4.72 | -58.51, -48.0 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-out | 8.1323 | D1228V | None | None | XRAY | 2.631 | 0.283 | 0.329 | C | 309.0 | 235.0 | 49 | 32 | 12 | 20 | [[1078, 1339]] | 1.0 | 8owg | Homo sapiens | TYR_MET_HUMAN | TYR | 1.5e-91 | 312.8 | 2.0 | 260.0 | 259.0 | 1221 | 1222 | 1223 | 1225 | 1227 | 1110 | 1127 | 1131 | 1201 | 1203 | 1202 | 1204.0 | 1265 | 1253 | 1248 | 1247 | 1246 | 1245 | 1244 | 1243 | 1242 | 1158 | Hepatocyte growth factor receptor |
| TYR | MET | MET_HUMAN | 8OW3A | P08581 | 1058 | 1345 | 1390.0 | W40:1401 | Type3 | Inactive | DFGout | 13.2821 | 6.9493 | BBAminus | -144.85, -172.89 | -148.19, 116.28 | -124.16, 31.55 | 280.56, 89.39 | -106.2, 999.0 | out-none | out | 12.6628 | Saltbr-none | 999.0 | HRD-in | -58.32, -54.99 | 72.45, -5.24 | none-none-none | SNCnnn | none-none | ActLoopNT-none | 999.0 | ActLoopCT-none | TYR | APEdihe_nniai | APEdist_aaai | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, 130.74 | APE8-dihe-in | -87.02, 65.42 | APE8-rot-na | 27.11 | APE67-dihe-in | -76.81, 1.52 | -53.65, -34.46 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-in | 7.7431 | None | None | None | XRAY | 2.27 | 0.247 | 0.295 | A | 309.0 | 258.0 | 30 | 32 | 12 | 20 | [[1078, 1339]] | 1.0 | 8ow3 | Homo sapiens | TYR_MET_HUMAN | TYR | 6.9e-92 | 313.9 | 2.0 | 260.0 | 259.0 | 1221 | 1222 | 1223 | 1225 | 1227 | 1110 | 1127 | 1131 | 1201 | 1203 | 1202 | 1204.0 | 1265 | 1253 | 1248 | 1247 | 1246 | 1245 | 1244 | 1243 | 1242 | 1158 | Hepatocyte growth factor receptor |
| Spatial label | Dihedral label | Number of Chains | Percent | Representative |
|---|
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|