Ligand: TC0

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 1 50.0% 4BBMB
DFGin None 1 50.0% 4BBMA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDKL2 CDKL2_HUMAN 4BBMB Q92772 1 308 493.0 TC0:60500 Type1 Inactive DFGin 7.0095 13.643 BLAplus -116.95, 172.46 71.25, 70.14 -140.96, 65.73 46.41, 86.58 130.11, -39.29 out-none out 11.912 Saltbr-none 999.0 HRD-in -66.2, -48.12 65.5, 13.04 none-out-out SNCnoo out-out ActLoopNT-out 10.2702 ActLoopCT-out nonTYR APEdihe_aaooi APEdist_iooo APE10-dihe-na -64.23, -50.52 APE9-dihe-na -57.38, -32.72 APE8-dihe-out -101.31, 4.49 APE8-rot-out 58.21 APE67-dihe-in -66.8, -18.02 -40.05, -47.42 APE12-dist-in 12.2798 APE11-dist-out 16.7739 APE10-dist-out 19.4327 APE9-dist-out 9.3923 T159D,Y161E None None XRAY 2.0 0.244 0.269 B 331.0 288.0 20 28 28 0 [[4, 287]] 1.0 4bbm CMGC_CDKL2_HUMAN CMGC 2.2e-79 272.8 1.0 301.0 301.0 143 144 145 147 149 33 51 55 123 125 124 126.0 184 171 166 165 164 163 162 161 160 81 Cyclin-dependent kinase-like 2
CMGC CDKL2 CDKL2_HUMAN 4BBMA Q92772 1 308 493.0 TC0:60500 Type1 Inactive DFGin 7.1518 13.3139 None -116.66, 173.28 70.79, 69.66 -144.2, 73.96 44.17, 99.05 132.17, -46.5 out-none out 11.8482 Saltbr-none 999.0 HRD-in -64.8, -48.49 65.16, 11.9 none-out-out SNCnoo out-out ActLoopNT-out 10.2517 ActLoopCT-out nonTYR APEdihe_aaooi APEdist_iooo APE10-dihe-na -63.85, -51.88 APE9-dihe-na -56.62, -32.94 APE8-dihe-out -101.86, 5.45 APE8-rot-out 58.5 APE67-dihe-in -66.8, -17.87 -40.06, -47.54 APE12-dist-in 12.3155 APE11-dist-out 16.808 APE10-dist-out 19.4627 APE9-dist-out 9.3714 T159D,Y161E None None XRAY 2.0 0.244 0.269 A 331.0 306.0 2 28 28 0 [[4, 287]] 1.0 4bbm CMGC_CDKL2_HUMAN CMGC 2.2e-79 272.8 1.0 301.0 301.0 143 144 145 147 149 33 51 55 123 125 124 126.0 184 171 166 165 164 163 162 161 160 81 Cyclin-dependent kinase-like 2

Ligand: TC0

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 1 50.0% 4BBMB
DFGin None 1 50.0% 4BBMA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDKL2 CDKL2_HUMAN 4BBMB Q92772 1 308 493.0 TC0:60500 Type1 Inactive DFGin 7.0095 13.643 BLAplus -116.95, 172.46 71.25, 70.14 -140.96, 65.73 46.41, 86.58 130.11, -39.29 out-none out 11.912 Saltbr-none 999.0 HRD-in -66.2, -48.12 65.5, 13.04 none-out-out SNCnoo out-out ActLoopNT-out 10.2702 ActLoopCT-out nonTYR APEdihe_aaooi APEdist_iooo APE10-dihe-na -64.23, -50.52 APE9-dihe-na -57.38, -32.72 APE8-dihe-out -101.31, 4.49 APE8-rot-out 58.21 APE67-dihe-in -66.8, -18.02 -40.05, -47.42 APE12-dist-in 12.2798 APE11-dist-out 16.7739 APE10-dist-out 19.4327 APE9-dist-out 9.3923 T159D,Y161E None None XRAY 2.0 0.244 0.269 B 331.0 288.0 20 28 28 0 [[4, 287]] 1.0 4bbm Homo sapiens CMGC_CDKL2_HUMAN CMGC 2.2e-79 272.8 1.0 301.0 301.0 143 144 145 147 149 33 51 55 123 125 124 126.0 184 171 166 165 164 163 162 161 160 81 Cyclin-dependent kinase-like 2
CMGC CDKL2 CDKL2_HUMAN 4BBMA Q92772 1 308 493.0 TC0:60500 Type1 Inactive DFGin 7.1518 13.3139 None -116.66, 173.28 70.79, 69.66 -144.2, 73.96 44.17, 99.05 132.17, -46.5 out-none out 11.8482 Saltbr-none 999.0 HRD-in -64.8, -48.49 65.16, 11.9 none-out-out SNCnoo out-out ActLoopNT-out 10.2517 ActLoopCT-out nonTYR APEdihe_aaooi APEdist_iooo APE10-dihe-na -63.85, -51.88 APE9-dihe-na -56.62, -32.94 APE8-dihe-out -101.86, 5.45 APE8-rot-out 58.5 APE67-dihe-in -66.8, -17.87 -40.06, -47.54 APE12-dist-in 12.3155 APE11-dist-out 16.808 APE10-dist-out 19.4627 APE9-dist-out 9.3714 T159D,Y161E None None XRAY 2.0 0.244 0.269 A 331.0 306.0 2 28 28 0 [[4, 287]] 1.0 4bbm Homo sapiens CMGC_CDKL2_HUMAN CMGC 2.2e-79 272.8 1.0 301.0 301.0 143 144 145 147 149 33 51 55 123 125 124 126.0 184 171 166 165 164 163 162 161 160 81 Cyclin-dependent kinase-like 2

Ligand: TC0

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name