Ligand: R78

Total number of chains: 7
Active chains: 1
Total number of genes: 3
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 7 100.0% 2RKUA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CAMK CAMKK2 KKCC2_HUMAN 6BQQA 1.8 Active DFGin‑BLAminus out-in in-in nonTYR APEdihe_aaiii APEdist_iiii R78 Type1 161 - 448 0 None None Calcium/calmodulin-dependent protein kinase kinase 2
CAMK PLK1 PLK1_HUMAN 9R8CA 2.243 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiio APEdist_ioio R78 Type1 38 - 326 0 None None Serine/threonine-protein kinase PLK1
CAMK PLK1 PLK1_HUMAN 9R8CB 2.243 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiio APEdist_ioio R78 Type1 38 - 323 0 None None Serine/threonine-protein kinase PLK1
CAMK PLK1 PLK1_HUMAN 2RKUA 1.95 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiio APEdist_ioio R78 Type1 37 - 330 0 None T210V Serine/threonine-protein kinase PLK1
CAMK PLK1 PLK1_HUMAN 9R1XA 2.84 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiio APEdist_ioio R78 Type1 39 - 334 0 None K225D,K226A Serine/threonine-protein kinase PLK1
CAMK PLK1 PLK1_HUMAN 9R1XB 2.84 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiio APEdist_ioio R78 Type1 39 - 326 0 None K225D,K226A Serine/threonine-protein kinase PLK1
CAMK PLK2 PLK2_HUMAN 4I5MA 1.801 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanoo APEdist_nnnn R78 Type1 71 - 354 0 None C83S,V87T,A119S,A216S,C259A,C291S,L335T Serine/threonine-protein kinase PLK2

Ligand: R78

Total number of chains: 7
Active chains: 1
Total number of genes: 3
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 7 100.0% 2RKUA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CAMK CAMKK2 KKCC2_HUMAN 6BQQA 1.8 Active DFGin‑BLAminus out-in in-in nonTYR APEdihe_aaiii APEdist_iiii R78 Type1 161 - 448 0 None None Calcium/calmodulin-dependent protein kinase kinase 2 Homo sapiens
CAMK PLK1 PLK1_HUMAN 9R8CA 2.243 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiio APEdist_ioio R78 Type1 38 - 326 0 None None Serine/threonine-protein kinase PLK1 Homo sapiens
CAMK PLK1 PLK1_HUMAN 9R8CB 2.243 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiio APEdist_ioio R78 Type1 38 - 323 0 None None Serine/threonine-protein kinase PLK1 Homo sapiens
CAMK PLK1 PLK1_HUMAN 2RKUA 1.95 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiio APEdist_ioio R78 Type1 37 - 330 0 None T210V Serine/threonine-protein kinase PLK1 Homo sapiens
CAMK PLK1 PLK1_HUMAN 9R1XA 2.84 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiio APEdist_ioio R78 Type1 39 - 334 0 None K225D,K226A Serine/threonine-protein kinase PLK1 Homo sapiens
CAMK PLK1 PLK1_HUMAN 9R1XB 2.84 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiio APEdist_ioio R78 Type1 39 - 326 0 None K225D,K226A Serine/threonine-protein kinase PLK1 Homo sapiens
CAMK PLK2 PLK2_HUMAN 4I5MA 1.801 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aanoo APEdist_nnnn R78 Type1 71 - 354 0 None C83S,V87T,A119S,A216S,C259A,C291S,L335T Serine/threonine-protein kinase PLK2 Homo sapiens

Ligand: R78

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism