Ligand: QFO

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 8D76A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 8D76A P00533 703 1014 1210.0 QFO:1504 Type1.5_Back Active DFGin 5.2885 14.4546 BLAminus -143.4, -172.03 76.83, 82.61 -101.19, 12.36 297.34, 100.87 -51.7, -27.33 in-in in 8.5534 Saltbr-in 2.6588 HRD-in -66.34, -53.39 73.14, 4.37 in-in-in SNCiii in-in ActLoopNT-in 2.8381 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -73.29, 128.72 APE9-dihe-in -125.98, 143.72 APE8-dihe-in -74.29, 76.55 APE8-rot-na 33.63 APE67-dihe-in -70.33, -10.53 -49.4, -47.68 APE12-dist-na 12.4069 APE11-dist-na 10.574 APE10-dist-na 11.3378 APE9-dist-in 7.0432 T790M,L858R,V948R None None XRAY 2.4 0.161 0.26 A 348.0 312.0 0 30 30 0 [[712, 970]] 1.0 8d76 TYR_EGFR_HUMAN TYR 7.7e-87 296.9 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8D76B P00533 702 1014 1210.0 QFO:1503 Type1.5_Back Active DFGin 5.2426 14.5156 BLAminus -142.04, -172.89 77.5, 81.63 -99.66, 12.37 297.26, 99.83 -52.91, -24.77 in-in in 8.5638 Saltbr-in 2.6543 HRD-in -65.39, -54.89 75.2, 3.17 in-in-in SNCiii in-in ActLoopNT-in 2.8426 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -74.34, 127.65 APE9-dihe-in -127.49, 143.46 APE8-dihe-in -75.23, 77.39 APE8-rot-na 35.03 APE67-dihe-in -70.18, -10.99 -49.52, -47.15 APE12-dist-na 12.4731 APE11-dist-na 10.719 APE10-dist-na 11.1884 APE9-dist-in 7.0494 T790M,L858R,V948R None None XRAY 2.4 0.161 0.26 B 348.0 313.0 0 30 30 0 [[712, 970]] 1.0 8d76 TYR_EGFR_HUMAN TYR 7.7e-87 296.9 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

Ligand: QFO

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 8D76A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 8D76A P00533 703 1014 1210.0 QFO:1504 Type1.5_Back Active DFGin 5.2885 14.4546 BLAminus -143.4, -172.03 76.83, 82.61 -101.19, 12.36 297.34, 100.87 -51.7, -27.33 in-in in 8.5534 Saltbr-in 2.6588 HRD-in -66.34, -53.39 73.14, 4.37 in-in-in SNCiii in-in ActLoopNT-in 2.8381 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -73.29, 128.72 APE9-dihe-in -125.98, 143.72 APE8-dihe-in -74.29, 76.55 APE8-rot-na 33.63 APE67-dihe-in -70.33, -10.53 -49.4, -47.68 APE12-dist-na 12.4069 APE11-dist-na 10.574 APE10-dist-na 11.3378 APE9-dist-in 7.0432 T790M,L858R,V948R None None XRAY 2.4 0.161 0.26 A 348.0 312.0 0 30 30 0 [[712, 970]] 1.0 8d76 Homo sapiens TYR_EGFR_HUMAN TYR 7.7e-87 296.9 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8D76B P00533 702 1014 1210.0 QFO:1503 Type1.5_Back Active DFGin 5.2426 14.5156 BLAminus -142.04, -172.89 77.5, 81.63 -99.66, 12.37 297.26, 99.83 -52.91, -24.77 in-in in 8.5638 Saltbr-in 2.6543 HRD-in -65.39, -54.89 75.2, 3.17 in-in-in SNCiii in-in ActLoopNT-in 2.8426 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -74.34, 127.65 APE9-dihe-in -127.49, 143.46 APE8-dihe-in -75.23, 77.39 APE8-rot-na 35.03 APE67-dihe-in -70.18, -10.99 -49.52, -47.15 APE12-dist-na 12.4731 APE11-dist-na 10.719 APE10-dist-na 11.1884 APE9-dist-in 7.0494 T790M,L858R,V948R None None XRAY 2.4 0.161 0.26 B 348.0 313.0 0 30 30 0 [[712, 970]] 1.0 8d76 Homo sapiens TYR_EGFR_HUMAN TYR 7.7e-87 296.9 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

Ligand: QFO

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name