Ligand: PP1

Total number of chains: 4
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 75.0% 2IVVA
DFGin BLBplus 1 25.0% 1QCFA

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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR HCK HCK_HUMAN 1QCFA 2.0 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao PP1 Type1 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK
TYR RET RET_HUMAN 2IVVA 2.25 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai PP1 Type1 703 - 1011 0 PTR905 None Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN 5FM2A 3.3 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai PP1 Type1 710 - 1011 0 PTR809,PTR905,SEP909,PTR928 None Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN 5FM3A 2.95 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai PP1 Type1 707 - 1011 0 PTR809,PTR905,SEP909,PTR928 None Proto-oncogene tyrosine-protein kinase receptor Ret

Ligand: PP1

Total number of chains: 4
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 75.0% 2IVVA
DFGin BLBplus 1 25.0% 1QCFA

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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR HCK HCK_HUMAN 1QCFA 2.0 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaao PP1 Type1 81 - 526 0 PTR522 Q523E,Q524E,Q525I Tyrosine-protein kinase HCK Homo sapiens
TYR RET RET_HUMAN 2IVVA 2.25 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai PP1 Type1 703 - 1011 0 PTR905 None Proto-oncogene tyrosine-protein kinase receptor Ret Homo sapiens
TYR RET RET_HUMAN 5FM2A 3.3 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai PP1 Type1 710 - 1011 0 PTR809,PTR905,SEP909,PTR928 None Proto-oncogene tyrosine-protein kinase receptor Ret Homo sapiens
TYR RET RET_HUMAN 5FM3A 2.95 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai PP1 Type1 707 - 1011 0 PTR809,PTR905,SEP909,PTR928 None Proto-oncogene tyrosine-protein kinase receptor Ret Homo sapiens

Ligand: PP1

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism