Ligand: PE4

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name

Ligand: PE4

Total number of chains: 3
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 66.7% 4Y95B
None None 1 33.3% 9EMYA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR BTK Q3ZC95_BOVIN 4Y95B Q3ZC95 395 659 659.0 746:60701,PE4:60705 Type1,Allosteric Inactive DFGin 6.2838 14.0698 BLBplus -118.87, 151.9 58.51, 36.48 -63.81, 131.39 36.51, 95.01 77.72, -1.04 out-out out 14.5981 Saltbr-out 16.1022 HRD-in -74.38, -57.15 83.98, -6.38 out-out-out SNCooo out-out ActLoopNT-out 8.1264 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaao APE10-dihe-out -110.28, -7.21 APE9-dihe-in -68.34, 135.25 APE8-dihe-in -80.18, 64.43 APE8-rot-na 29.96 APE67-dihe-in -80.41, -0.39 -53.51, -41.68 APE12-dist-na 17.4878 APE11-dist-na 18.9412 APE10-dist-na 13.9012 APE9-dist-out 8.7509 L542M,S543T,Y545F,V555T,S557T,R562K,S564A,P565S,Y617P None None XRAY 1.599 0.155 0.184 B 266.0 265.0 0 29 29 0 [[402, 653]] 1.0 4y95 Bos taurus TYR_BTK_BOVIN TYR 1.4e-93 318.9 1.0 258.0 258.0 538 539 540 542 544 430 445 449 518 520 519 521.0 579 567 562 561 560 559 558 557 556 475 Tyrosine-protein kinase
TYR BTK Q3ZC95_BOVIN 4Y95C Q3ZC95 395 659 659.0 746:61001,PE4:61004 Type1,Allosteric Inactive DFGin 6.2611 14.0342 BLBplus -119.16, 152.8 57.59, 36.19 -63.2, 130.69 37.21, 95.75 78.07, -1.63 out-out out 14.6057 Saltbr-out 16.1522 HRD-in -74.98, -51.44 82.75, -9.25 out-out-out SNCooo out-out ActLoopNT-out 8.1038 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaao APE10-dihe-out -111.01, -6.79 APE9-dihe-in -68.05, 136.6 APE8-dihe-in -80.31, 63.53 APE8-rot-na 30.49 APE67-dihe-in -79.73, -0.13 -53.01, -42.36 APE12-dist-na 17.506 APE11-dist-na 18.9727 APE10-dist-na 13.9266 APE9-dist-out 8.8005 L542M,S543T,Y545F,V555T,S557T,R562K,S564A,P565S,Y617P None None XRAY 1.599 0.155 0.184 C 266.0 265.0 0 29 29 0 [[402, 653]] 1.0 4y95 Bos taurus TYR_BTK_BOVIN TYR 1.4e-93 318.9 1.0 258.0 258.0 538 539 540 542 544 430 445 449 518 520 519 521.0 579 567 562 561 560 559 558 557 556 475 Tyrosine-protein kinase
OTHER CK2024380 A0A2I0BRS6_PLAFO 9EMYA A0A2I0BRS6 157 561 561.0 AGS:601,PE4:602 ATPlike,Allosteric Inactive None 999.0 999.0 None -141.05, 146.83 102.18, -104.97 80.11, 29.42 313.02, 18.48 -97.07, -12.64 none-na none 999.0 Saltbr-na 999.0 HRD-na- -113.81, -67.49 68.91, 22.97 na-in-in SNCaii in-in ActLoopNT-in 2.9972 ActLoopCT-in nonTYR APEdihe_aaiai APEdist_iiii APE10-dihe-na -133.3, 137.35 APE9-dihe-na 55.54, -152.24 APE8-dihe-in -84.79, 148.26 APE8-rot-na 286.36 APE67-dihe-in -66.38, -33.03 -58.56, -29.39 APE12-dist-in 12.5559 APE11-dist-in 9.9876 APE10-dist-in 6.4693 APE9-dist-in 3.566 None None None XRAY 2.814 0.245 0.286 A 413.0 370.0 43 41 41 0 [[30, 557]] 1.0 9emy Plasmodium falciparum OTHER_CK2024380_PLAFO CAMK 2.1e-05 40.5 53.0 169.0 169.0 397 398 399 401 403 0 0 0 376 378 377 379.0 0 438 433 432 431 430 429 428 427 328 non-specific serine/threonine protein kinase

Ligand: PE4

Total number of chains: 3
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 66.7% 4Y95B
None None 1 33.3% 9EMYA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR BTK Q3ZC95_BOVIN 4Y95B Q3ZC95 395 659 659.0 746:60701,PE4:60705 Type1,Allosteric Inactive DFGin 6.2838 14.0698 BLBplus -118.87, 151.9 58.51, 36.48 -63.81, 131.39 36.51, 95.01 77.72, -1.04 out-out out 14.5981 Saltbr-out 16.1022 HRD-in -74.38, -57.15 83.98, -6.38 out-out-out SNCooo out-out ActLoopNT-out 8.1264 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaao APE10-dihe-out -110.28, -7.21 APE9-dihe-in -68.34, 135.25 APE8-dihe-in -80.18, 64.43 APE8-rot-na 29.96 APE67-dihe-in -80.41, -0.39 -53.51, -41.68 APE12-dist-na 17.4878 APE11-dist-na 18.9412 APE10-dist-na 13.9012 APE9-dist-out 8.7509 L542M,S543T,Y545F,V555T,S557T,R562K,S564A,P565S,Y617P None None XRAY 1.599 0.155 0.184 B 266.0 265.0 0 29 29 0 [[402, 653]] 1.0 4y95 Bos taurus TYR_BTK_BOVIN TYR 1.4e-93 318.9 1.0 258.0 258.0 538 539 540 542 544 430 445 449 518 520 519 521.0 579 567 562 561 560 559 558 557 556 475 Tyrosine-protein kinase
TYR BTK Q3ZC95_BOVIN 4Y95C Q3ZC95 395 659 659.0 746:61001,PE4:61004 Type1,Allosteric Inactive DFGin 6.2611 14.0342 BLBplus -119.16, 152.8 57.59, 36.19 -63.2, 130.69 37.21, 95.75 78.07, -1.63 out-out out 14.6057 Saltbr-out 16.1522 HRD-in -74.98, -51.44 82.75, -9.25 out-out-out SNCooo out-out ActLoopNT-out 8.1038 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaao APE10-dihe-out -111.01, -6.79 APE9-dihe-in -68.05, 136.6 APE8-dihe-in -80.31, 63.53 APE8-rot-na 30.49 APE67-dihe-in -79.73, -0.13 -53.01, -42.36 APE12-dist-na 17.506 APE11-dist-na 18.9727 APE10-dist-na 13.9266 APE9-dist-out 8.8005 L542M,S543T,Y545F,V555T,S557T,R562K,S564A,P565S,Y617P None None XRAY 1.599 0.155 0.184 C 266.0 265.0 0 29 29 0 [[402, 653]] 1.0 4y95 Bos taurus TYR_BTK_BOVIN TYR 1.4e-93 318.9 1.0 258.0 258.0 538 539 540 542 544 430 445 449 518 520 519 521.0 579 567 562 561 560 559 558 557 556 475 Tyrosine-protein kinase
OTHER CK2024380 A0A2I0BRS6_PLAFO 9EMYA A0A2I0BRS6 157 561 561.0 AGS:601,PE4:602 ATPlike,Allosteric Inactive None 999.0 999.0 None -141.05, 146.83 102.18, -104.97 80.11, 29.42 313.02, 18.48 -97.07, -12.64 none-na none 999.0 Saltbr-na 999.0 HRD-na- -113.81, -67.49 68.91, 22.97 na-in-in SNCaii in-in ActLoopNT-in 2.9972 ActLoopCT-in nonTYR APEdihe_aaiai APEdist_iiii APE10-dihe-na -133.3, 137.35 APE9-dihe-na 55.54, -152.24 APE8-dihe-in -84.79, 148.26 APE8-rot-na 286.36 APE67-dihe-in -66.38, -33.03 -58.56, -29.39 APE12-dist-in 12.5559 APE11-dist-in 9.9876 APE10-dist-in 6.4693 APE9-dist-in 3.566 None None None XRAY 2.814 0.245 0.286 A 413.0 370.0 43 41 41 0 [[30, 557]] 1.0 9emy Plasmodium falciparum OTHER_CK2024380_PLAFO CAMK 2.1e-05 40.5 53.0 169.0 169.0 397 398 399 401 403 0 0 0 376 378 377 379.0 0 438 433 432 431 430 429 428 427 328 non-specific serine/threonine protein kinase