Ligand: P17

Total number of chains: 1
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBminus 1 100.0% 5IA3A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EPHA2 EPHA2_HUMAN 5IA3A P29317 602 896 976.0 P17:1001 Type1 Inactive DFGin 6.2436 14.848 BLBminus -140.25, -177.97 75.12, 87.33 -118.87, 162.99 296.17, 108.02 122.4, -163.0 in-in in 8.3214 Saltbr-in 2.6488 HRD-in -77.68, -48.9 76.3, -15.94 in-out-none SNCion out-none ActLoopNT-out 9.2666 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 154.55 APE8-dihe-in -79.35, 94.2 APE8-rot-na 29.88 APE67-dihe-in -64.17, -17.19 -57.49, -47.32 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 6.6412 None None None XRAY 1.788 0.163 0.204 A 306.0 275.0 20 31 15 16 [[613, 873]] 1.0 5ia3 TYR_EPHA2_HUMAN TYR 5.5e-108 366.1 2.0 261.0 260.0 756 757 758 760 762 646 663 667 736 738 737 739.0 799 787 782 781 780 779 778 777 776 693 Ephrin type-A receptor 2

Ligand: P17

Total number of chains: 3
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGout None 2 66.7% 1M52A
DFGin BLBminus 1 33.3% 5IA3A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EPHA2 EPHA2_HUMAN 5IA3A P29317 602 896 976.0 P17:1001 Type1 Inactive DFGin 6.2436 14.848 BLBminus -140.25, -177.97 75.12, 87.33 -118.87, 162.99 296.17, 108.02 122.4, -163.0 in-in in 8.3214 Saltbr-in 2.6488 HRD-in -77.68, -48.9 76.3, -15.94 in-out-none SNCion out-none ActLoopNT-out 9.2666 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 154.55 APE8-dihe-in -79.35, 94.2 APE8-rot-na 29.88 APE67-dihe-in -64.17, -17.19 -57.49, -47.32 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 6.6412 None None None XRAY 1.788 0.163 0.204 A 306.0 275.0 20 31 15 16 [[613, 873]] 1.0 5ia3 Homo sapiens TYR_EPHA2_HUMAN TYR 5.5e-108 366.1 2.0 261.0 260.0 756 757 758 760 762 646 663 667 736 738 737 739.0 799 787 782 781 780 779 778 777 776 693 Ephrin type-A receptor 2
TYR ABL1 ABL1_MOUSE 1M52A P00520 232 502 1123.0 P17:119 Type1.5_Back Inactive DFGout 12.7932 10.7534 None -60.22, 138.56 -89.44, -13.76 -71.29, 150.54 62.03, 63.6 85.22, 23.45 in-in in 7.8946 Saltbr-in 2.7072 HRD-out -103.5, 129.11 -84.41, -9.26 in-out-in SNCioi out-in ActLoopNT-out 5.5228 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -102.32, 126.97 APE9-dihe-in -125.58, 158.53 APE8-dihe-in -60.22, 106.23 APE8-rot-na 28.98 APE67-dihe-in -61.13, -15.48 -48.91, -53.77 APE12-dist-na 18.5358 APE11-dist-na 14.0518 APE10-dist-na 17.1001 APE9-dist-in 6.3399 None None None XRAY 2.6 0.211 0.254 A 293.0 271.0 0 29 29 0 [[242, 495]] 1.0 1m52 Mus musculus TYR_ABL1_MOUSE TYR 2.9e-100 340.8 1.0 260.0 260.0 380 381 382 384 386 271 286 290 360 362 361 363.0 421 409 404 403 402 401 400 399 398 316 Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_MOUSE 1M52B P00520 232 503 1123.0 P17:120 Type1.5_Back Inactive DFGout 12.7809 10.9966 None -67.54, 135.07 -84.58, -12.33 -70.24, 151.37 63.17, 66.62 85.76, 18.68 in-in in 8.0957 Saltbr-in 2.8231 HRD-out -106.35, 123.08 -78.82, -9.36 in-out-in SNCioi out-in ActLoopNT-out 5.5791 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -108.32, 130.43 APE9-dihe-in -127.38, 164.85 APE8-dihe-in -67.06, 104.95 APE8-rot-na 28.73 APE67-dihe-in -58.93, -14.72 -46.9, -55.31 APE12-dist-na 18.9417 APE11-dist-na 14.1825 APE10-dist-na 17.0323 APE9-dist-in 6.3696 None None None XRAY 2.6 0.211 0.254 B 293.0 272.0 0 29 29 0 [[242, 495]] 1.0 1m52 Mus musculus TYR_ABL1_MOUSE TYR 2.9e-100 340.8 1.0 260.0 260.0 380 381 382 384 386 271 286 290 360 362 361 363.0 421 409 404 403 402 401 400 399 398 316 Tyrosine-protein kinase ABL1

Ligand: P17

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout None 2 100.0% 1M52A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR ABL1 ABL1_MOUSE 1M52A P00520 232 502 1123.0 P17:119 Type1.5_Back Inactive DFGout 12.7932 10.7534 None -60.22, 138.56 -89.44, -13.76 -71.29, 150.54 62.03, 63.6 85.22, 23.45 in-in in 7.8946 Saltbr-in 2.7072 HRD-out -103.5, 129.11 -84.41, -9.26 in-out-in SNCioi out-in ActLoopNT-out 5.5228 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -102.32, 126.97 APE9-dihe-in -125.58, 158.53 APE8-dihe-in -60.22, 106.23 APE8-rot-na 28.98 APE67-dihe-in -61.13, -15.48 -48.91, -53.77 APE12-dist-na 18.5358 APE11-dist-na 14.0518 APE10-dist-na 17.1001 APE9-dist-in 6.3399 None None None XRAY 2.6 0.211 0.254 A 293.0 271.0 0 29 29 0 [[242, 495]] 1.0 1m52 Mus musculus TYR_ABL1_MOUSE TYR 2.9e-100 340.8 1.0 260.0 260.0 380 381 382 384 386 271 286 290 360 362 361 363.0 421 409 404 403 402 401 400 399 398 316 Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_MOUSE 1M52B P00520 232 503 1123.0 P17:120 Type1.5_Back Inactive DFGout 12.7809 10.9966 None -67.54, 135.07 -84.58, -12.33 -70.24, 151.37 63.17, 66.62 85.76, 18.68 in-in in 8.0957 Saltbr-in 2.8231 HRD-out -106.35, 123.08 -78.82, -9.36 in-out-in SNCioi out-in ActLoopNT-out 5.5791 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -108.32, 130.43 APE9-dihe-in -127.38, 164.85 APE8-dihe-in -67.06, 104.95 APE8-rot-na 28.73 APE67-dihe-in -58.93, -14.72 -46.9, -55.31 APE12-dist-na 18.9417 APE11-dist-na 14.1825 APE10-dist-na 17.0323 APE9-dist-in 6.3696 None None None XRAY 2.6 0.211 0.254 B 293.0 272.0 0 29 29 0 [[242, 495]] 1.0 1m52 Mus musculus TYR_ABL1_MOUSE TYR 2.9e-100 340.8 1.0 260.0 260.0 380 381 382 384 386 271 286 290 360 362 361 363.0 421 409 404 403 402 401 400 399 398 316 Tyrosine-protein kinase ABL1