Ligand: OWQ

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 50.0% 6YKYB
DFGinter None 2 50.0% 6YKYD

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CMGC MAPK6 MK06_HUMAN 6YKYB 2.52 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iooo OWQ Type1 16 - 321 0 None L290V Mitogen-activated protein kinase 6
CMGC MAPK6 MK06_HUMAN 6YKYC 2.52 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_oooo OWQ Type1 13 - 319 0 None L290V Mitogen-activated protein kinase 6
CMGC MAPK6 MK06_HUMAN 6YKYA 2.52 Inactive DFGinter‑None in-out out-out nonTYR APEdihe_aaioi APEdist_oooo OWQ Type1 18 - 319 0 None L290V Mitogen-activated protein kinase 6
CMGC MAPK6 MK06_HUMAN 6YKYD 2.52 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaioi APEdist_oooo OWQ Type1 14 - 321 0 None L290V Mitogen-activated protein kinase 6

Ligand: OWQ

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 50.0% 6YKYB
DFGinter None 2 50.0% 6YKYD

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC MAPK6 MK06_HUMAN 6YKYB 2.52 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iooo OWQ Type1 16 - 321 0 None L290V Mitogen-activated protein kinase 6 Homo sapiens
CMGC MAPK6 MK06_HUMAN 6YKYC 2.52 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_oooo OWQ Type1 13 - 319 0 None L290V Mitogen-activated protein kinase 6 Homo sapiens
CMGC MAPK6 MK06_HUMAN 6YKYA 2.52 Inactive DFGinter‑None in-out out-out nonTYR APEdihe_aaioi APEdist_oooo OWQ Type1 18 - 319 0 None L290V Mitogen-activated protein kinase 6 Homo sapiens
CMGC MAPK6 MK06_HUMAN 6YKYD 2.52 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaioi APEdist_oooo OWQ Type1 14 - 321 0 None L290V Mitogen-activated protein kinase 6 Homo sapiens

Ligand: OWQ

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism