Ligand: OFQ

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name

Ligand: OFQ

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 6Y7XA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK14 MK14_MOUSE 6Y7XA P47811 5 359 360.0 SB4:401,OFQ:407 Type1,Allosteric Inactive DFGin 5.8376 14.1423 BLBplus -140.52, 171.9 59.02, 32.21 -87.93, 160.25 46.31, 91.31 62.16, 18.97 in-in in 9.0815 Saltbr-in 2.6196 HRD-in -74.68, -57.27 79.25, -15.98 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nooo APE10-dihe-na -117.66, 121.28 APE9-dihe-na -97.49, 147.27 APE8-dihe-in -70.48, 139.23 APE8-rot-out 189.8 APE67-dihe-in -64.63, -20.63 -107.94, 3.51 APE12-dist-none 999.0 APE11-dist-out 14.2773 APE10-dist-out 17.7869 APE9-dist-out 10.699 C162S None None XRAY 1.45 0.211 0.229 A 360.0 345.0 10 25 15 10 [[24, 308]] 1.0 6y7x Mus musculus CMGC_MAPK14_MOUSE CMGC 5.1e-85 291.4 1.0 301.0 301.0 167 168 169 171 173 53 71 75 147 149 148 150.0 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_MOUSE 6Y7YA P47811 6 359 360.0 SB4:401,OFQ:407,LOT:408,LOT:409 Type1,Allosteric,Allosteric,Allosteric Inactive DFGin 5.5985 14.0658 BLBplus -134.15, 167.21 61.56, 33.57 -84.2, 154.3 46.03, 91.51 71.1, 10.08 in-in in 9.0829 Saltbr-in 2.4631 HRD-in -77.03, -55.9 76.47, -10.86 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnoo APE10-dihe-na 999.0, 124.77 APE9-dihe-na -96.71, 148.3 APE8-dihe-in -61.68, 139.31 APE8-rot-in 301.71 APE67-dihe-in -65.13, -20.59 -107.51, 1.3 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 17.6132 APE9-dist-out 10.7375 C162S None None XRAY 1.51 0.221 0.248 A 360.0 343.0 11 25 14 11 [[24, 308]] 1.0 6y7y Mus musculus CMGC_MAPK14_MOUSE CMGC 5.1e-85 291.4 1.0 301.0 301.0 167 168 169 171 173 53 71 75 147 149 148 150.0 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14

Ligand: OFQ

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 6Y7XA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK14 MK14_MOUSE 6Y7XA P47811 5 359 360.0 SB4:401,OFQ:407 Type1,Allosteric Inactive DFGin 5.8376 14.1423 BLBplus -140.52, 171.9 59.02, 32.21 -87.93, 160.25 46.31, 91.31 62.16, 18.97 in-in in 9.0815 Saltbr-in 2.6196 HRD-in -74.68, -57.27 79.25, -15.98 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nooo APE10-dihe-na -117.66, 121.28 APE9-dihe-na -97.49, 147.27 APE8-dihe-in -70.48, 139.23 APE8-rot-out 189.8 APE67-dihe-in -64.63, -20.63 -107.94, 3.51 APE12-dist-none 999.0 APE11-dist-out 14.2773 APE10-dist-out 17.7869 APE9-dist-out 10.699 C162S None None XRAY 1.45 0.211 0.229 A 360.0 345.0 10 25 15 10 [[24, 308]] 1.0 6y7x Mus musculus CMGC_MAPK14_MOUSE CMGC 5.1e-85 291.4 1.0 301.0 301.0 167 168 169 171 173 53 71 75 147 149 148 150.0 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_MOUSE 6Y7YA P47811 6 359 360.0 SB4:401,OFQ:407,LOT:408,LOT:409 Type1,Allosteric,Allosteric,Allosteric Inactive DFGin 5.5985 14.0658 BLBplus -134.15, 167.21 61.56, 33.57 -84.2, 154.3 46.03, 91.51 71.1, 10.08 in-in in 9.0829 Saltbr-in 2.4631 HRD-in -77.03, -55.9 76.47, -10.86 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnoo APE10-dihe-na 999.0, 124.77 APE9-dihe-na -96.71, 148.3 APE8-dihe-in -61.68, 139.31 APE8-rot-in 301.71 APE67-dihe-in -65.13, -20.59 -107.51, 1.3 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 17.6132 APE9-dist-out 10.7375 C162S None None XRAY 1.51 0.221 0.248 A 360.0 343.0 11 25 14 11 [[24, 308]] 1.0 6y7y Mus musculus CMGC_MAPK14_MOUSE CMGC 5.1e-85 291.4 1.0 301.0 301.0 167 168 169 171 173 53 71 75 147 149 148 150.0 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14