Ligand: O2H

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 2 100.0% 6XVBA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR KIT KIT_HUMAN 6XVBA P10721 569 931 976.0 O2H:61001 Type2 Inactive DFGout 15.6964 10.0195 BBAminus -139.93, -171.17 -149.97, 98.79 -62.06, -36.15 280.7, 79.89 52.82, -116.74 in-in in 7.6264 Saltbr-in 2.7761 HRD-in -70.55, -51.81 77.37, -9.25 in-out-in SNCioi out-in ActLoopNT-out 16.5394 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -114.91, 97.58 APE9-dihe-in -112.95, 149.34 APE8-dihe-in -83.11, 69.81 APE8-rot-na 31.26 APE67-dihe-in -62.03, -20.02 -53.33, -41.4 APE12-dist-na 16.8544 APE11-dist-na 13.5971 APE10-dist-na 11.2319 APE9-dist-in 7.8174 I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 2.15 0.194 0.223 A 328.0 285.0 0 30 30 0 [[589, 926]] 1.0 6xvb TYR_KIT_HUMAN TYR 2.4e-104 354.2 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 6XVBB P10721 577 931 976.0 O2H:61001 Type2 Inactive DFGout 15.8149 10.0306 BBAminus -139.72, -172.06 -151.07, 100.84 -60.77, -37.85 279.63, 78.82 52.08, -117.31 in-in in 7.6339 Saltbr-in 2.778 HRD-in -66.84, -49.22 76.63, -10.21 in-out-in SNCioi out-in ActLoopNT-out 16.489 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -114.62, 98.9 APE9-dihe-in -115.12, 149.29 APE8-dihe-in -83.95, 69.91 APE8-rot-na 30.96 APE67-dihe-in -63.32, -19.92 -52.16, -41.56 APE12-dist-na 16.981 APE11-dist-na 13.7679 APE10-dist-na 11.2594 APE9-dist-in 7.8642 I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 2.15 0.194 0.223 B 328.0 277.0 0 30 30 0 [[589, 926]] 1.0 6xvb TYR_KIT_HUMAN TYR 2.4e-104 354.2 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit

Ligand: O2H

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 2 100.0% 6XVBA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR KIT KIT_HUMAN 6XVBA P10721 569 931 976.0 O2H:61001 Type2 Inactive DFGout 15.6964 10.0195 BBAminus -139.93, -171.17 -149.97, 98.79 -62.06, -36.15 280.7, 79.89 52.82, -116.74 in-in in 7.6264 Saltbr-in 2.7761 HRD-in -70.55, -51.81 77.37, -9.25 in-out-in SNCioi out-in ActLoopNT-out 16.5394 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -114.91, 97.58 APE9-dihe-in -112.95, 149.34 APE8-dihe-in -83.11, 69.81 APE8-rot-na 31.26 APE67-dihe-in -62.03, -20.02 -53.33, -41.4 APE12-dist-na 16.8544 APE11-dist-na 13.5971 APE10-dist-na 11.2319 APE9-dist-in 7.8174 I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 2.15 0.194 0.223 A 328.0 285.0 0 30 30 0 [[589, 926]] 1.0 6xvb Homo sapiens TYR_KIT_HUMAN TYR 2.4e-104 354.2 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 6XVBB P10721 577 931 976.0 O2H:61001 Type2 Inactive DFGout 15.8149 10.0306 BBAminus -139.72, -172.06 -151.07, 100.84 -60.77, -37.85 279.63, 78.82 52.08, -117.31 in-in in 7.6339 Saltbr-in 2.778 HRD-in -66.84, -49.22 76.63, -10.21 in-out-in SNCioi out-in ActLoopNT-out 16.489 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -114.62, 98.9 APE9-dihe-in -115.12, 149.29 APE8-dihe-in -83.95, 69.91 APE8-rot-na 30.96 APE67-dihe-in -63.32, -19.92 -52.16, -41.56 APE12-dist-na 16.981 APE11-dist-na 13.7679 APE10-dist-na 11.2594 APE9-dist-in 7.8642 I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 2.15 0.194 0.223 B 328.0 277.0 0 30 30 0 [[589, 926]] 1.0 6xvb Homo sapiens TYR_KIT_HUMAN TYR 2.4e-104 354.2 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit

Ligand: O2H

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name