Ligand: NQ1

Total number of chains: 6
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 6 100.0% 6P1DB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 6P1DB P00533 702 1013 1210.0 ANP:1101,NQ1:1102 ATPlike,Type3 Inactive DFGin 4.7371 14.0299 BLBplus -133.29, 171.5 64.7, 17.77 -68.3, 145.06 52.12, 92.58 81.65, -14.38 out-out out 13.7895 Saltbr-out 14.416 HRD-in -75.11, -58.04 81.02, -12.96 out-out-out SNCooo out-out ActLoopNT-out 6.3903 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, -53.71 APE8-dihe-in -78.39, 61.97 APE8-rot-na 34.06 APE67-dihe-in -73.46, -6.67 -54.96, -43.14 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.3559 None None None XRAY 2.4 0.195 0.213 B 327.0 300.0 12 30 18 12 [[712, 970]] 1.0 6p1d TYR_EGFR_HUMAN TYR 6e-88 300.6 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6XL4D P00533 700 1013 1210.0 ANP:1102,NQ1:1103 ATPlike,Type3 Inactive DFGin 4.8901 14.2469 BLBplus -133.2, 175.82 65.76, 18.85 -77.15, 145.6 52.8, 92.59 74.56, -2.19 out-out out 13.6236 Saltbr-out 15.8297 HRD-in -71.69, -57.79 76.59, -4.88 out-out-none SNCoon out-none ActLoopNT-out 6.4776 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 139.17 APE8-dihe-in -78.79, 71.74 APE8-rot-na 31.74 APE67-dihe-in -74.38, -1.99 -55.71, -41.48 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.7702 T790M,V948R None None XRAY 2.06 0.216 0.252 D 328.0 300.0 14 30 19 11 [[712, 970]] 1.0 6xl4 TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6XL4A P00533 700 1007 1210.0 Q6K:1301,NQ1:1302 Type1,Type3 Inactive DFGin 5.0977 14.695 BLBplus -134.42, 176.69 66.92, 16.35 -78.69, 146.78 51.46, 92.89 75.99, 3.76 out-out out 13.3627 Saltbr-out 12.5385 HRD-in -71.16, -58.13 77.59, -5.31 out-out-none SNCoon out-none ActLoopNT-out 7.3856 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 139.31 APE8-dihe-in -78.15, 72.0 APE8-rot-na 31.9 APE67-dihe-in -74.09, -1.62 -55.44, -42.27 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.703 T790M,V948R None None XRAY 2.06 0.216 0.252 A 328.0 293.0 15 30 15 15 [[712, 970]] 1.0 6xl4 TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6P1DC P00533 702 1006 1210.0 NQ1:1101,ANP:1102 Type3,ATPlike Inactive DFGin 5.3825 14.4593 BLBplus -142.0, 171.97 66.8, 29.01 -86.08, 152.7 44.82, 92.23 73.36, -11.9 out-out out 13.6137 Saltbr-out 13.7361 HRD-in -69.23, -60.69 76.65, -2.9 out-out-none SNCoon out-none ActLoopNT-out 6.7847 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 96.45 APE8-dihe-in -76.51, 79.09 APE8-rot-na 31.04 APE67-dihe-in -75.49, -1.74 -58.74, -40.16 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.2578 None None None XRAY 2.4 0.195 0.213 C 327.0 292.0 13 30 17 13 [[712, 970]] 1.0 6p1d TYR_EGFR_HUMAN TYR 6e-88 300.6 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6P1DD P00533 701 1008 1210.0 NQ1:1101,ANP:1102 Type3,ATPlike Inactive DFGin 4.7963 14.1019 BLBplus -132.01, 171.13 65.01, 17.93 -68.87, 143.86 51.94, 90.04 79.55, -15.22 out-out out 13.6224 Saltbr-out 13.7342 HRD-in -75.21, -58.43 80.83, -11.58 out-out-none SNCoon out-none ActLoopNT-out 6.6334 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 114.5 APE8-dihe-in -78.23, 70.43 APE8-rot-na 33.16 APE67-dihe-in -74.16, -5.23 -50.48, -45.29 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.2506 None None None XRAY 2.4 0.195 0.213 D 327.0 295.0 13 30 17 13 [[712, 970]] 1.0 6p1d TYR_EGFR_HUMAN TYR 6e-88 300.6 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6XL4B P00533 700 1007 1210.0 NQ1:1201,Q6K:1202 Type3,Type1 Inactive DFGin 4.8081 14.4972 BLBplus -133.43, 176.08 66.75, 17.79 -78.7, 146.83 53.41, 93.69 78.85, 14.72 out-out out 13.8089 Saltbr-out 14.2239 HRD-in -71.6, -57.82 77.95, -5.56 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 139.66 APE8-dihe-in -77.94, 72.67 APE8-rot-na 31.42 APE67-dihe-in -72.46, -3.15 -55.35, -40.72 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.9321 T790M,V948R None None XRAY 2.06 0.216 0.252 B 328.0 292.0 16 30 14 16 [[712, 970]] 1.0 6xl4 TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

Ligand: NQ1

Total number of chains: 6
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 6 100.0% 6P1DB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 6P1DB P00533 702 1013 1210.0 ANP:1101,NQ1:1102 ATPlike,Type3 Inactive DFGin 4.7371 14.0299 BLBplus -133.29, 171.5 64.7, 17.77 -68.3, 145.06 52.12, 92.58 81.65, -14.38 out-out out 13.7895 Saltbr-out 14.416 HRD-in -75.11, -58.04 81.02, -12.96 out-out-out SNCooo out-out ActLoopNT-out 6.3903 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, -53.71 APE8-dihe-in -78.39, 61.97 APE8-rot-na 34.06 APE67-dihe-in -73.46, -6.67 -54.96, -43.14 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.3559 None None None XRAY 2.4 0.195 0.213 B 327.0 300.0 12 30 18 12 [[712, 970]] 1.0 6p1d Homo sapiens TYR_EGFR_HUMAN TYR 6e-88 300.6 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6XL4D P00533 700 1013 1210.0 ANP:1102,NQ1:1103 ATPlike,Type3 Inactive DFGin 4.8901 14.2469 BLBplus -133.2, 175.82 65.76, 18.85 -77.15, 145.6 52.8, 92.59 74.56, -2.19 out-out out 13.6236 Saltbr-out 15.8297 HRD-in -71.69, -57.79 76.59, -4.88 out-out-none SNCoon out-none ActLoopNT-out 6.4776 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 139.17 APE8-dihe-in -78.79, 71.74 APE8-rot-na 31.74 APE67-dihe-in -74.38, -1.99 -55.71, -41.48 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.7702 T790M,V948R None None XRAY 2.06 0.216 0.252 D 328.0 300.0 14 30 19 11 [[712, 970]] 1.0 6xl4 Homo sapiens TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6XL4A P00533 700 1007 1210.0 Q6K:1301,NQ1:1302 Type1,Type3 Inactive DFGin 5.0977 14.695 BLBplus -134.42, 176.69 66.92, 16.35 -78.69, 146.78 51.46, 92.89 75.99, 3.76 out-out out 13.3627 Saltbr-out 12.5385 HRD-in -71.16, -58.13 77.59, -5.31 out-out-none SNCoon out-none ActLoopNT-out 7.3856 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 139.31 APE8-dihe-in -78.15, 72.0 APE8-rot-na 31.9 APE67-dihe-in -74.09, -1.62 -55.44, -42.27 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.703 T790M,V948R None None XRAY 2.06 0.216 0.252 A 328.0 293.0 15 30 15 15 [[712, 970]] 1.0 6xl4 Homo sapiens TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6P1DC P00533 702 1006 1210.0 NQ1:1101,ANP:1102 Type3,ATPlike Inactive DFGin 5.3825 14.4593 BLBplus -142.0, 171.97 66.8, 29.01 -86.08, 152.7 44.82, 92.23 73.36, -11.9 out-out out 13.6137 Saltbr-out 13.7361 HRD-in -69.23, -60.69 76.65, -2.9 out-out-none SNCoon out-none ActLoopNT-out 6.7847 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 96.45 APE8-dihe-in -76.51, 79.09 APE8-rot-na 31.04 APE67-dihe-in -75.49, -1.74 -58.74, -40.16 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.2578 None None None XRAY 2.4 0.195 0.213 C 327.0 292.0 13 30 17 13 [[712, 970]] 1.0 6p1d Homo sapiens TYR_EGFR_HUMAN TYR 6e-88 300.6 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6P1DD P00533 701 1008 1210.0 NQ1:1101,ANP:1102 Type3,ATPlike Inactive DFGin 4.7963 14.1019 BLBplus -132.01, 171.13 65.01, 17.93 -68.87, 143.86 51.94, 90.04 79.55, -15.22 out-out out 13.6224 Saltbr-out 13.7342 HRD-in -75.21, -58.43 80.83, -11.58 out-out-none SNCoon out-none ActLoopNT-out 6.6334 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 114.5 APE8-dihe-in -78.23, 70.43 APE8-rot-na 33.16 APE67-dihe-in -74.16, -5.23 -50.48, -45.29 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.2506 None None None XRAY 2.4 0.195 0.213 D 327.0 295.0 13 30 17 13 [[712, 970]] 1.0 6p1d Homo sapiens TYR_EGFR_HUMAN TYR 6e-88 300.6 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6XL4B P00533 700 1007 1210.0 NQ1:1201,Q6K:1202 Type3,Type1 Inactive DFGin 4.8081 14.4972 BLBplus -133.43, 176.08 66.75, 17.79 -78.7, 146.83 53.41, 93.69 78.85, 14.72 out-out out 13.8089 Saltbr-out 14.2239 HRD-in -71.6, -57.82 77.95, -5.56 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 139.66 APE8-dihe-in -77.94, 72.67 APE8-rot-na 31.42 APE67-dihe-in -72.46, -3.15 -55.35, -40.72 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.9321 T790M,V948R None None XRAY 2.06 0.216 0.252 B 328.0 292.0 16 30 14 16 [[712, 970]] 1.0 6xl4 Homo sapiens TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

Ligand: NQ1

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name