Ligand: NIO

Total number of chains: 15
Active chains: 12
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 15 100.0% 3WARA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CSNK2A1 CSK21_HUMAN 7B8HA P68400 2 330 391.0 NIO:402 Type1 Inactive DFGin 7.488 16.195 BLAminus -118.3, -177.98 52.84, 76.26 -89.68, 18.81 295.79, 83.41 -71.54, -15.88 in-in in 9.115 Saltbr-in 2.681 HRD-in -74.51, -48.01 71.61, 6.44 in-in-out SNCiio in-out ActLoopNT-in 2.876 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -130.06, 169.87 APE9-dihe-na 66.5, 155.23 APE8-dihe-in -84.17, 146.52 APE8-rot-out 183.74 APE67-dihe-in -71.73, -12.94 -41.65, -53.92 APE12-dist-in 12.722 APE11-dist-in 10.434 APE10-dist-in 6.268 APE9-dist-in 3.288 None None None XRAY 1.34 0.154 0.164 A 335 329 0 0 0 0 [[39, 324]] 1.0 7b8h CMGC_CSNK2A1_HUMAN CMGC 1.3e-69 240.6 1 301 301 174 175 176 178 180 68 81 85 153 155 154 156 214 201 196 195 194 193 192 191 190 114 Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 3WARA P68400 2 335 391.0 NIO:401 Type1 Active DFGin 7.398 16.333 BLAminus -118.01, -179.19 53.54, 74.9 -88.25, 17.65 295.66, 81.42 -73.21, -11.49 in-in in 9.327 Saltbr-in 2.722 HRD-in -72.59, -52.65 70.79, 14.03 in-in-in SNCiii in-in ActLoopNT-in 2.885 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -134.99, 174.6 APE9-dihe-na 63.08, -176.3 APE8-dihe-in -110.61, 145.61 APE8-rot-in 299.39 APE67-dihe-in -70.25, -13.59 -38.58, -54.17 APE12-dist-in 12.391 APE11-dist-in 9.888 APE10-dist-in 6.029 APE9-dist-in 3.03 None None None XRAY 1.04 0.145 0.168 A 340 334 0 0 0 0 [[39, 324]] 1.0 3war CMGC_CSNK2A1_HUMAN CMGC 1.4e-69 240.5 1 301 301 174 175 176 178 180 68 81 85 153 155 154 156 214 201 196 195 194 193 192 191 190 114 Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 9FBLA P68400 2 331 391.0 NIO:401 Type1 Active DFGin 7.561 16.415 BLAminus -119.09, -175.4 55.42, 82.25 -102.19, 28.43 298.2, 82.55 -71.05, -23.95 in-in in 9.573 Saltbr-in 2.436 HRD-in -71.22, -45.57 63.94, 21.51 in-in-in SNCiii in-in ActLoopNT-in 3.122 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -125.31, 167.35 APE9-dihe-na 63.26, 173.37 APE8-dihe-in -84.48, 159.03 APE8-rot-in 297.46 APE67-dihe-in -70.04, -3.97 -57.65, -48.08 APE12-dist-in 12.89 APE11-dist-in 10.713 APE10-dist-in 6.25 APE9-dist-in 3.269 None None None XRAY 2.18 0.21 0.266 A 349 330 0 0 0 0 [[39, 324]] 1.0 9fbl CMGC_CSNK2A1_HUMAN CMGC 1.5e-69 240.4 1 301 301 174 175 176 178 180 68 81 85 153 155 154 156 214 201 196 195 194 193 192 191 190 114 Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 9FBLB P68400 1 331 391.0 NIO:401 Type1 Active DFGin 7.513 16.384 BLAminus -119.56, -174.49 55.83, 81.57 -103.36, 28.47 297.98, 82.77 -71.16, -24.43 in-in in 9.838 Saltbr-in 2.873 HRD-in -71.01, -45.55 63.87, 20.68 in-in-in SNCiii in-in ActLoopNT-in 3.05 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -126.81, 167.4 APE9-dihe-na 62.93, 172.99 APE8-dihe-in -84.32, 157.55 APE8-rot-in 297.76 APE67-dihe-in -69.51, -4.14 -57.8, -46.91 APE12-dist-in 12.826 APE11-dist-in 10.675 APE10-dist-in 6.26 APE9-dist-in 3.426 None None None XRAY 2.18 0.21 0.266 B 349 331 0 0 0 0 [[39, 324]] 1.0 9fbl CMGC_CSNK2A1_HUMAN CMGC 1.5e-69 240.4 1 301 301 174 175 176 178 180 68 81 85 153 155 154 156 214 201 196 195 194 193 192 191 190 114 Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 9FBLC P68400 3 331 391.0 NIO:401 Type1 Active DFGin 7.623 16.277 BLAminus -119.42, -175.04 55.55, 81.6 -102.74, 28.54 298.97, 82.55 -71.14, -24.43 in-in in 9.415 Saltbr-in 2.779 HRD-in -70.51, -45.42 63.69, 20.2 in-in-in SNCiii in-in ActLoopNT-in 3.068 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -126.42, 167.77 APE9-dihe-na 63.12, 173.26 APE8-dihe-in -84.37, 157.16 APE8-rot-in 297.91 APE67-dihe-in -69.09, -4.73 -58.53, -46.52 APE12-dist-in 12.855 APE11-dist-in 10.791 APE10-dist-in 6.255 APE9-dist-in 3.456 None None None XRAY 2.18 0.21 0.266 C 349 329 0 0 0 0 [[39, 324]] 1.0 9fbl CMGC_CSNK2A1_HUMAN CMGC 1.5e-69 240.4 1 301 301 174 175 176 178 180 68 81 85 153 155 154 156 214 201 196 195 194 193 192 191 190 114 Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 9FBMA P68400 2 332 391.0 NIO:401 Type1 Active DFGin 7.498 16.117 BLAminus -119.62, -176.97 53.46, 77.76 -92.78, 22.73 297.42, 82.27 -70.9, -19.59 in-in in 9.096 Saltbr-in 2.735 HRD-in -72.75, -48.09 73.71, 7.18 in-in-in SNCiii in-in ActLoopNT-in 2.953 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -129.61, 171.81 APE9-dihe-na 65.01, 167.04 APE8-dihe-in -87.68, 149.39 APE8-rot-in 301.3 APE67-dihe-in -66.06, -18.0 -47.8, -48.12 APE12-dist-in 12.972 APE11-dist-in 11.015 APE10-dist-in 6.336 APE9-dist-in 3.515 None None None XRAY 2.054 0.185 0.239 A 349 331 0 0 0 0 [[39, 324]] 1.0 9fbm CMGC_CSNK2A1_HUMAN CMGC 1.5e-69 240.4 1 301 301 174 175 176 178 180 68 81 85 153 155 154 156 214 201 196 195 194 193 192 191 190 114 Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 9FBMB P68400 1 332 391.0 NIO:401 Type1 Active DFGin 7.651 16.51 BLAminus -120.4, -177.22 54.37, 76.23 -93.8, 22.33 298.21, 80.64 -70.16, -18.71 in-in in 9.562 Saltbr-in 2.763 HRD-in -72.52, -48.38 72.95, 4.97 in-in-in SNCiii in-in ActLoopNT-in 3.0 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -129.7, 170.6 APE9-dihe-na 64.16, 167.35 APE8-dihe-in -85.46, 150.13 APE8-rot-in 300.04 APE67-dihe-in -65.72, -18.18 -48.88, -49.5 APE12-dist-in 12.935 APE11-dist-in 11.002 APE10-dist-in 6.417 APE9-dist-in 3.538 None None None XRAY 2.054 0.185 0.239 B 349 332 0 0 0 0 [[39, 324]] 1.0 9fbm CMGC_CSNK2A1_HUMAN CMGC 1.5e-69 240.4 1 301 301 174 175 176 178 180 68 81 85 153 155 154 156 214 201 196 195 194 193 192 191 190 114 Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 9FBMC P68400 2 332 391.0 NIO:401 Type1 Active DFGin 7.43 16.131 BLAminus -121.01, -178.14 54.27, 76.82 -92.08, 24.16 297.19, 80.1 -71.19, -20.24 in-in in 9.235 Saltbr-in 2.546 HRD-in -73.21, -49.65 73.41, 6.63 in-in-in SNCiii in-in ActLoopNT-in 3.001 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -128.42, 172.87 APE9-dihe-na 65.35, 168.24 APE8-dihe-in -89.12, 150.36 APE8-rot-in 298.19 APE67-dihe-in -66.08, -18.21 -48.28, -50.63 APE12-dist-in 12.744 APE11-dist-in 10.763 APE10-dist-in 6.263 APE9-dist-in 3.252 None None None XRAY 2.054 0.185 0.239 C 349 331 0 0 0 0 [[39, 324]] 1.0 9fbm CMGC_CSNK2A1_HUMAN CMGC 1.5e-69 240.4 1 301 301 174 175 176 178 180 68 81 85 153 155 154 156 214 201 196 195 194 193 192 191 190 114 Casein kinase II subunit alpha
CMGC CSNK2A2 CSK22_HUMAN 5Y9MA P19784 7 329 350.0 NIO:401 Type1 Active DFGin 7.413 16.17 BLAminus -114.7, 179.98 51.13, 80.68 -91.85, 19.14 294.67, 80.42 -65.77, -17.09 in-in in 9.364 Saltbr-in 2.718 HRD-in -70.56, -47.51 66.93, 6.34 in-in-in SNCiii in-in ActLoopNT-in 2.81 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -139.58, 175.14 APE9-dihe-na 60.0, -172.23 APE8-dihe-in -119.82, 146.83 APE8-rot-in 298.24 APE67-dihe-in -67.32, -19.61 -42.77, -51.22 APE12-dist-in 12.724 APE11-dist-in 10.493 APE10-dist-in 6.152 APE9-dist-in 3.013 None None None XRAY 2.006 0.173 0.205 A 339 320 3 0 0 0 [[40, 325]] 1.0 5y9m CMGC_CSNK2A2_HUMAN CMGC 8.1e-70 241.3 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CMGC CSNK2A2 CSK22_HUMAN 5Y9MX P19784 7 329 350.0 NIO:401 Type1 Active DFGin 7.419 16.296 BLAminus -114.61, -179.34 52.3, 79.76 -91.76, 19.36 295.38, 79.95 -64.7, -18.3 in-in in 9.336 Saltbr-in 2.717 HRD-in -70.29, -48.55 67.93, 5.94 in-in-in SNCiii in-in ActLoopNT-in 2.806 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -138.82, 175.26 APE9-dihe-na 61.28, -171.63 APE8-dihe-in -117.63, 147.87 APE8-rot-in 296.65 APE67-dihe-in -67.57, -18.73 -43.97, -52.04 APE12-dist-in 12.753 APE11-dist-in 10.798 APE10-dist-in 6.257 APE9-dist-in 3.052 None None None XRAY 2.006 0.173 0.205 X 339 319 4 0 0 0 [[40, 325]] 1.0 5y9m CMGC_CSNK2A2_HUMAN CMGC 8.1e-70 241.3 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CMGC CSNK2A2 CSK22_HUMAN 5YF9B P19784 6 329 350.0 NIO:401 Type1 Active DFGin 7.459 16.07 BLAminus -110.95, -179.27 53.65, 80.05 -91.28, 26.14 296.96, 82.34 -75.04, -13.81 in-in in 9.343 Saltbr-in 2.569 HRD-in -67.49, -46.45 66.2, 15.42 in-in-in SNCiii in-in ActLoopNT-in 2.969 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -129.9, 174.16 APE9-dihe-na 64.72, 177.19 APE8-dihe-in -102.79, 146.68 APE8-rot-in 285.72 APE67-dihe-in -62.8, -17.43 -42.57, -55.43 APE12-dist-in 12.715 APE11-dist-in 10.521 APE10-dist-in 6.167 APE9-dist-in 3.05 None None None XRAY 1.89 0.214 0.263 B 339 319 5 0 0 0 [[40, 325]] 1.0 5yf9 CMGC_CSNK2A2_HUMAN CMGC 8.1e-70 241.3 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CMGC CSNK2A2 CSK22_HUMAN 5YF9X P19784 6 329 350.0 NIO:401 Type1 Active DFGin 7.455 16.124 BLAminus -110.45, 178.76 52.99, 85.82 -99.51, 23.76 294.09, 79.0 -68.33, -18.31 in-in in 9.319 Saltbr-in 2.715 HRD-in -73.65, -40.36 65.12, 8.62 in-in-in SNCiii in-in ActLoopNT-in 2.874 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -127.77, 173.49 APE9-dihe-na 70.21, 177.5 APE8-dihe-in -110.25, 140.72 APE8-rot-in 310.64 APE67-dihe-in -61.7, -20.77 -30.8, -60.11 APE12-dist-in 12.649 APE11-dist-in 10.499 APE10-dist-in 6.199 APE9-dist-in 2.948 None None None XRAY 1.89 0.214 0.263 X 339 319 5 0 0 0 [[40, 325]] 1.0 5yf9 CMGC_CSNK2A2_HUMAN CMGC 8.1e-70 241.3 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CMGC CSNK2A2 CSK22_HUMAN 5YWMX P19784 7 329 350.0 NIO:403 Type1 Active DFGin 7.404 16.019 BLAminus -123.21, -176.41 54.46, 76.29 -96.72, 23.28 298.12, 81.76 -77.51, -13.54 in-in in 9.387 Saltbr-in 2.599 HRD-in -75.02, -47.07 66.38, 11.61 in-in-in SNCiii in-in ActLoopNT-in 2.845 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -111.96, 178.56 APE9-dihe-na 63.18, 172.28 APE8-dihe-in -91.07, 141.04 APE8-rot-in 301.46 APE67-dihe-in -66.16, -20.07 -36.63, -51.01 APE12-dist-in 12.942 APE11-dist-in 11.12 APE10-dist-in 6.107 APE9-dist-in 3.168 None None None XRAY 1.939 0.195 0.243 X 339 313 10 0 0 0 [[40, 325]] 1.0 5ywm CMGC_CSNK2A2_HUMAN CMGC 8.1e-70 241.3 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CMGC CSNK2A2 CSK22_HUMAN 9FBIA P19784 7 333 350.0 NIO:401 Type1 Inactive DFGin 7.398 16.126 BLAminus -117.51, 178.09 54.8, 75.35 -88.6, 16.43 294.32, 81.79 -66.23, -19.3 in-in in 9.236 Saltbr-in 2.845 HRD-in -76.16, -47.39 73.52, 9.76 in-in-out SNCiio in-out ActLoopNT-in 2.892 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -133.37, 166.15 APE9-dihe-na 70.34, 154.33 APE8-dihe-in -71.36, 149.29 APE8-rot-out 153.93 APE67-dihe-in -72.01, -15.91 -47.59, -45.82 APE12-dist-in 12.469 APE11-dist-in 10.094 APE10-dist-in 6.031 APE9-dist-in 3.362 C336S None None XRAY 1.161 0.146 0.185 A 364 327 0 0 0 0 [[40, 325]] 1.0 9fbi CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CMGC CSNK2A2 CSK22_HUMAN 9FBIB P19784 5 333 350.0 NIO:401 Type1 Inactive DFGin 7.471 16.3 BLAminus -116.61, 178.26 54.58, 80.03 -91.17, 14.79 296.76, 82.15 -70.7, -15.45 in-in in 9.643 Saltbr-in 2.697 HRD-in -74.94, -47.04 69.95, 13.58 in-in-out SNCiio in-out ActLoopNT-in 2.872 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -136.62, 165.93 APE9-dihe-na 67.12, 156.73 APE8-dihe-in -70.88, 146.98 APE8-rot-out 150.31 APE67-dihe-in -70.99, -16.75 -44.95, -47.09 APE12-dist-in 12.635 APE11-dist-in 10.43 APE10-dist-in 6.209 APE9-dist-in 3.336 C336S None None XRAY 1.161 0.146 0.185 B 364 329 0 0 0 0 [[40, 325]] 1.0 9fbi CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'

Ligand: NIO

Total number of chains: 15
Active chains: 12
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 15 100.0% 3WARA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CSNK2A1 CSK21_HUMAN 7B8HA P68400 2 330 391.0 NIO:402 Type1 Inactive DFGin 7.488 16.195 BLAminus -118.3, -177.98 52.84, 76.26 -89.68, 18.81 295.79, 83.41 -71.54, -15.88 in-in in 9.115 Saltbr-in 2.681 HRD-in -74.51, -48.01 71.61, 6.44 in-in-out SNCiio in-out ActLoopNT-in 2.876 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -130.06, 169.87 APE9-dihe-na 66.5, 155.23 APE8-dihe-in -84.17, 146.52 APE8-rot-out 183.74 APE67-dihe-in -71.73, -12.94 -41.65, -53.92 APE12-dist-in 12.722 APE11-dist-in 10.434 APE10-dist-in 6.268 APE9-dist-in 3.288 None None None XRAY 1.34 0.154 0.164 A 335 329 0 0 0 0 [[39, 324]] 1.0 7b8h Homo sapiens CMGC_CSNK2A1_HUMAN CMGC 1.3e-69 240.6 1 301 301 174 175 176 178 180 68 81 85 153 155 154 156 214 201 196 195 194 193 192 191 190 114 Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 3WARA P68400 2 335 391.0 NIO:401 Type1 Active DFGin 7.398 16.333 BLAminus -118.01, -179.19 53.54, 74.9 -88.25, 17.65 295.66, 81.42 -73.21, -11.49 in-in in 9.327 Saltbr-in 2.722 HRD-in -72.59, -52.65 70.79, 14.03 in-in-in SNCiii in-in ActLoopNT-in 2.885 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -134.99, 174.6 APE9-dihe-na 63.08, -176.3 APE8-dihe-in -110.61, 145.61 APE8-rot-in 299.39 APE67-dihe-in -70.25, -13.59 -38.58, -54.17 APE12-dist-in 12.391 APE11-dist-in 9.888 APE10-dist-in 6.029 APE9-dist-in 3.03 None None None XRAY 1.04 0.145 0.168 A 340 334 0 0 0 0 [[39, 324]] 1.0 3war Homo sapiens CMGC_CSNK2A1_HUMAN CMGC 1.4e-69 240.5 1 301 301 174 175 176 178 180 68 81 85 153 155 154 156 214 201 196 195 194 193 192 191 190 114 Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 9FBLA P68400 2 331 391.0 NIO:401 Type1 Active DFGin 7.561 16.415 BLAminus -119.09, -175.4 55.42, 82.25 -102.19, 28.43 298.2, 82.55 -71.05, -23.95 in-in in 9.573 Saltbr-in 2.436 HRD-in -71.22, -45.57 63.94, 21.51 in-in-in SNCiii in-in ActLoopNT-in 3.122 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -125.31, 167.35 APE9-dihe-na 63.26, 173.37 APE8-dihe-in -84.48, 159.03 APE8-rot-in 297.46 APE67-dihe-in -70.04, -3.97 -57.65, -48.08 APE12-dist-in 12.89 APE11-dist-in 10.713 APE10-dist-in 6.25 APE9-dist-in 3.269 None None None XRAY 2.18 0.21 0.266 A 349 330 0 0 0 0 [[39, 324]] 1.0 9fbl Homo sapiens CMGC_CSNK2A1_HUMAN CMGC 1.5e-69 240.4 1 301 301 174 175 176 178 180 68 81 85 153 155 154 156 214 201 196 195 194 193 192 191 190 114 Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 9FBLB P68400 1 331 391.0 NIO:401 Type1 Active DFGin 7.513 16.384 BLAminus -119.56, -174.49 55.83, 81.57 -103.36, 28.47 297.98, 82.77 -71.16, -24.43 in-in in 9.838 Saltbr-in 2.873 HRD-in -71.01, -45.55 63.87, 20.68 in-in-in SNCiii in-in ActLoopNT-in 3.05 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -126.81, 167.4 APE9-dihe-na 62.93, 172.99 APE8-dihe-in -84.32, 157.55 APE8-rot-in 297.76 APE67-dihe-in -69.51, -4.14 -57.8, -46.91 APE12-dist-in 12.826 APE11-dist-in 10.675 APE10-dist-in 6.26 APE9-dist-in 3.426 None None None XRAY 2.18 0.21 0.266 B 349 331 0 0 0 0 [[39, 324]] 1.0 9fbl Homo sapiens CMGC_CSNK2A1_HUMAN CMGC 1.5e-69 240.4 1 301 301 174 175 176 178 180 68 81 85 153 155 154 156 214 201 196 195 194 193 192 191 190 114 Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 9FBLC P68400 3 331 391.0 NIO:401 Type1 Active DFGin 7.623 16.277 BLAminus -119.42, -175.04 55.55, 81.6 -102.74, 28.54 298.97, 82.55 -71.14, -24.43 in-in in 9.415 Saltbr-in 2.779 HRD-in -70.51, -45.42 63.69, 20.2 in-in-in SNCiii in-in ActLoopNT-in 3.068 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -126.42, 167.77 APE9-dihe-na 63.12, 173.26 APE8-dihe-in -84.37, 157.16 APE8-rot-in 297.91 APE67-dihe-in -69.09, -4.73 -58.53, -46.52 APE12-dist-in 12.855 APE11-dist-in 10.791 APE10-dist-in 6.255 APE9-dist-in 3.456 None None None XRAY 2.18 0.21 0.266 C 349 329 0 0 0 0 [[39, 324]] 1.0 9fbl Homo sapiens CMGC_CSNK2A1_HUMAN CMGC 1.5e-69 240.4 1 301 301 174 175 176 178 180 68 81 85 153 155 154 156 214 201 196 195 194 193 192 191 190 114 Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 9FBMA P68400 2 332 391.0 NIO:401 Type1 Active DFGin 7.498 16.117 BLAminus -119.62, -176.97 53.46, 77.76 -92.78, 22.73 297.42, 82.27 -70.9, -19.59 in-in in 9.096 Saltbr-in 2.735 HRD-in -72.75, -48.09 73.71, 7.18 in-in-in SNCiii in-in ActLoopNT-in 2.953 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -129.61, 171.81 APE9-dihe-na 65.01, 167.04 APE8-dihe-in -87.68, 149.39 APE8-rot-in 301.3 APE67-dihe-in -66.06, -18.0 -47.8, -48.12 APE12-dist-in 12.972 APE11-dist-in 11.015 APE10-dist-in 6.336 APE9-dist-in 3.515 None None None XRAY 2.054 0.185 0.239 A 349 331 0 0 0 0 [[39, 324]] 1.0 9fbm Homo sapiens CMGC_CSNK2A1_HUMAN CMGC 1.5e-69 240.4 1 301 301 174 175 176 178 180 68 81 85 153 155 154 156 214 201 196 195 194 193 192 191 190 114 Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 9FBMB P68400 1 332 391.0 NIO:401 Type1 Active DFGin 7.651 16.51 BLAminus -120.4, -177.22 54.37, 76.23 -93.8, 22.33 298.21, 80.64 -70.16, -18.71 in-in in 9.562 Saltbr-in 2.763 HRD-in -72.52, -48.38 72.95, 4.97 in-in-in SNCiii in-in ActLoopNT-in 3.0 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -129.7, 170.6 APE9-dihe-na 64.16, 167.35 APE8-dihe-in -85.46, 150.13 APE8-rot-in 300.04 APE67-dihe-in -65.72, -18.18 -48.88, -49.5 APE12-dist-in 12.935 APE11-dist-in 11.002 APE10-dist-in 6.417 APE9-dist-in 3.538 None None None XRAY 2.054 0.185 0.239 B 349 332 0 0 0 0 [[39, 324]] 1.0 9fbm Homo sapiens CMGC_CSNK2A1_HUMAN CMGC 1.5e-69 240.4 1 301 301 174 175 176 178 180 68 81 85 153 155 154 156 214 201 196 195 194 193 192 191 190 114 Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 9FBMC P68400 2 332 391.0 NIO:401 Type1 Active DFGin 7.43 16.131 BLAminus -121.01, -178.14 54.27, 76.82 -92.08, 24.16 297.19, 80.1 -71.19, -20.24 in-in in 9.235 Saltbr-in 2.546 HRD-in -73.21, -49.65 73.41, 6.63 in-in-in SNCiii in-in ActLoopNT-in 3.001 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -128.42, 172.87 APE9-dihe-na 65.35, 168.24 APE8-dihe-in -89.12, 150.36 APE8-rot-in 298.19 APE67-dihe-in -66.08, -18.21 -48.28, -50.63 APE12-dist-in 12.744 APE11-dist-in 10.763 APE10-dist-in 6.263 APE9-dist-in 3.252 None None None XRAY 2.054 0.185 0.239 C 349 331 0 0 0 0 [[39, 324]] 1.0 9fbm Homo sapiens CMGC_CSNK2A1_HUMAN CMGC 1.5e-69 240.4 1 301 301 174 175 176 178 180 68 81 85 153 155 154 156 214 201 196 195 194 193 192 191 190 114 Casein kinase II subunit alpha
CMGC CSNK2A2 CSK22_HUMAN 5Y9MA P19784 7 329 350.0 NIO:401 Type1 Active DFGin 7.413 16.17 BLAminus -114.7, 179.98 51.13, 80.68 -91.85, 19.14 294.67, 80.42 -65.77, -17.09 in-in in 9.364 Saltbr-in 2.718 HRD-in -70.56, -47.51 66.93, 6.34 in-in-in SNCiii in-in ActLoopNT-in 2.81 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -139.58, 175.14 APE9-dihe-na 60.0, -172.23 APE8-dihe-in -119.82, 146.83 APE8-rot-in 298.24 APE67-dihe-in -67.32, -19.61 -42.77, -51.22 APE12-dist-in 12.724 APE11-dist-in 10.493 APE10-dist-in 6.152 APE9-dist-in 3.013 None None None XRAY 2.006 0.173 0.205 A 339 320 3 0 0 0 [[40, 325]] 1.0 5y9m Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 8.1e-70 241.3 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CMGC CSNK2A2 CSK22_HUMAN 5Y9MX P19784 7 329 350.0 NIO:401 Type1 Active DFGin 7.419 16.296 BLAminus -114.61, -179.34 52.3, 79.76 -91.76, 19.36 295.38, 79.95 -64.7, -18.3 in-in in 9.336 Saltbr-in 2.717 HRD-in -70.29, -48.55 67.93, 5.94 in-in-in SNCiii in-in ActLoopNT-in 2.806 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -138.82, 175.26 APE9-dihe-na 61.28, -171.63 APE8-dihe-in -117.63, 147.87 APE8-rot-in 296.65 APE67-dihe-in -67.57, -18.73 -43.97, -52.04 APE12-dist-in 12.753 APE11-dist-in 10.798 APE10-dist-in 6.257 APE9-dist-in 3.052 None None None XRAY 2.006 0.173 0.205 X 339 319 4 0 0 0 [[40, 325]] 1.0 5y9m Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 8.1e-70 241.3 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CMGC CSNK2A2 CSK22_HUMAN 5YF9B P19784 6 329 350.0 NIO:401 Type1 Active DFGin 7.459 16.07 BLAminus -110.95, -179.27 53.65, 80.05 -91.28, 26.14 296.96, 82.34 -75.04, -13.81 in-in in 9.343 Saltbr-in 2.569 HRD-in -67.49, -46.45 66.2, 15.42 in-in-in SNCiii in-in ActLoopNT-in 2.969 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -129.9, 174.16 APE9-dihe-na 64.72, 177.19 APE8-dihe-in -102.79, 146.68 APE8-rot-in 285.72 APE67-dihe-in -62.8, -17.43 -42.57, -55.43 APE12-dist-in 12.715 APE11-dist-in 10.521 APE10-dist-in 6.167 APE9-dist-in 3.05 None None None XRAY 1.89 0.214 0.263 B 339 319 5 0 0 0 [[40, 325]] 1.0 5yf9 Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 8.1e-70 241.3 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CMGC CSNK2A2 CSK22_HUMAN 5YF9X P19784 6 329 350.0 NIO:401 Type1 Active DFGin 7.455 16.124 BLAminus -110.45, 178.76 52.99, 85.82 -99.51, 23.76 294.09, 79.0 -68.33, -18.31 in-in in 9.319 Saltbr-in 2.715 HRD-in -73.65, -40.36 65.12, 8.62 in-in-in SNCiii in-in ActLoopNT-in 2.874 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -127.77, 173.49 APE9-dihe-na 70.21, 177.5 APE8-dihe-in -110.25, 140.72 APE8-rot-in 310.64 APE67-dihe-in -61.7, -20.77 -30.8, -60.11 APE12-dist-in 12.649 APE11-dist-in 10.499 APE10-dist-in 6.199 APE9-dist-in 2.948 None None None XRAY 1.89 0.214 0.263 X 339 319 5 0 0 0 [[40, 325]] 1.0 5yf9 Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 8.1e-70 241.3 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CMGC CSNK2A2 CSK22_HUMAN 5YWMX P19784 7 329 350.0 NIO:403 Type1 Active DFGin 7.404 16.019 BLAminus -123.21, -176.41 54.46, 76.29 -96.72, 23.28 298.12, 81.76 -77.51, -13.54 in-in in 9.387 Saltbr-in 2.599 HRD-in -75.02, -47.07 66.38, 11.61 in-in-in SNCiii in-in ActLoopNT-in 2.845 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -111.96, 178.56 APE9-dihe-na 63.18, 172.28 APE8-dihe-in -91.07, 141.04 APE8-rot-in 301.46 APE67-dihe-in -66.16, -20.07 -36.63, -51.01 APE12-dist-in 12.942 APE11-dist-in 11.12 APE10-dist-in 6.107 APE9-dist-in 3.168 None None None XRAY 1.939 0.195 0.243 X 339 313 10 0 0 0 [[40, 325]] 1.0 5ywm Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 8.1e-70 241.3 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CMGC CSNK2A2 CSK22_HUMAN 9FBIA P19784 7 333 350.0 NIO:401 Type1 Inactive DFGin 7.398 16.126 BLAminus -117.51, 178.09 54.8, 75.35 -88.6, 16.43 294.32, 81.79 -66.23, -19.3 in-in in 9.236 Saltbr-in 2.845 HRD-in -76.16, -47.39 73.52, 9.76 in-in-out SNCiio in-out ActLoopNT-in 2.892 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -133.37, 166.15 APE9-dihe-na 70.34, 154.33 APE8-dihe-in -71.36, 149.29 APE8-rot-out 153.93 APE67-dihe-in -72.01, -15.91 -47.59, -45.82 APE12-dist-in 12.469 APE11-dist-in 10.094 APE10-dist-in 6.031 APE9-dist-in 3.362 C336S None None XRAY 1.161 0.146 0.185 A 364 327 0 0 0 0 [[40, 325]] 1.0 9fbi Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CMGC CSNK2A2 CSK22_HUMAN 9FBIB P19784 5 333 350.0 NIO:401 Type1 Inactive DFGin 7.471 16.3 BLAminus -116.61, 178.26 54.58, 80.03 -91.17, 14.79 296.76, 82.15 -70.7, -15.45 in-in in 9.643 Saltbr-in 2.697 HRD-in -74.94, -47.04 69.95, 13.58 in-in-out SNCiio in-out ActLoopNT-in 2.872 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -136.62, 165.93 APE9-dihe-na 67.12, 156.73 APE8-dihe-in -70.88, 146.98 APE8-rot-out 150.31 APE67-dihe-in -70.99, -16.75 -44.95, -47.09 APE12-dist-in 12.635 APE11-dist-in 10.43 APE10-dist-in 6.209 APE9-dist-in 3.336 C336S None None XRAY 1.161 0.146 0.185 B 364 329 0 0 0 0 [[40, 325]] 1.0 9fbi Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'

Ligand: NIO

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name