Ligand: M2Z

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 6SZMB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 6SZMA Q04771 202 499 509.0 M2Z:501,M2Z:502,M2Z:503 Allosteric,Allosteric,Type1 Inactive DFGin 8.3731 13.3835 BLAminus -123.47, 160.72 76.41, 88.39 -99.15, 24.41 296.86, 175.6 -67.43, -19.78 in-out in 9.1097 Saltbr-out 5.9058 HRD-in -80.16, -50.98 77.51, 1.34 out-in-out SNCoio in-out ActLoopNT-in 2.8981 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -127.99, 159.14 APE9-dihe-na -78.06, -171.02 APE8-dihe-in -67.19, 128.07 APE8-rot-in 301.51 APE67-dihe-in -54.87, -30.28 -61.82, -41.68 APE12-dist-in 10.1324 APE11-dist-out 6.4105 APE10-dist-out 9.2993 APE9-dist-in 3.6403 None None None XRAY 1.42 0.154 0.188 A 301.0 288.0 10 32 22 10 [[207, 497]] 1.0 6szm TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 6SZMB Q04771 205 499 509.0 M2Z:501 Type1 Inactive DFGin 6.8892 13.3795 BLAminus -130.45, 165.06 76.0, 85.65 -99.23, 20.14 303.49, 173.6 -70.24, -14.21 in-out in 8.8543 Saltbr-out 4.7163 HRD-in -80.29, -50.69 76.82, 0.43 out-in-out SNCoio in-out ActLoopNT-in 2.943 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -119.93, 162.59 APE9-dihe-na -62.54, 170.01 APE8-dihe-in -65.85, 128.73 APE8-rot-in 300.13 APE67-dihe-in -58.84, -26.54 -57.25, -44.85 APE12-dist-in 10.3092 APE11-dist-out 6.2858 APE10-dist-out 9.0768 APE9-dist-in 3.7758 None None None XRAY 1.42 0.154 0.188 B 301.0 295.0 0 32 32 0 [[207, 497]] 1.0 6szm TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

Ligand: M2Z

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 6SZMB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 6SZMA Q04771 202 499 509.0 M2Z:501,M2Z:502,M2Z:503 Allosteric,Allosteric,Type1 Inactive DFGin 8.3731 13.3835 BLAminus -123.47, 160.72 76.41, 88.39 -99.15, 24.41 296.86, 175.6 -67.43, -19.78 in-out in 9.1097 Saltbr-out 5.9058 HRD-in -80.16, -50.98 77.51, 1.34 out-in-out SNCoio in-out ActLoopNT-in 2.8981 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -127.99, 159.14 APE9-dihe-na -78.06, -171.02 APE8-dihe-in -67.19, 128.07 APE8-rot-in 301.51 APE67-dihe-in -54.87, -30.28 -61.82, -41.68 APE12-dist-in 10.1324 APE11-dist-out 6.4105 APE10-dist-out 9.2993 APE9-dist-in 3.6403 None None None XRAY 1.42 0.154 0.188 A 301.0 288.0 10 32 22 10 [[207, 497]] 1.0 6szm Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 6SZMB Q04771 205 499 509.0 M2Z:501 Type1 Inactive DFGin 6.8892 13.3795 BLAminus -130.45, 165.06 76.0, 85.65 -99.23, 20.14 303.49, 173.6 -70.24, -14.21 in-out in 8.8543 Saltbr-out 4.7163 HRD-in -80.29, -50.69 76.82, 0.43 out-in-out SNCoio in-out ActLoopNT-in 2.943 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -119.93, 162.59 APE9-dihe-na -62.54, 170.01 APE8-dihe-in -65.85, 128.73 APE8-rot-in 300.13 APE67-dihe-in -58.84, -26.54 -57.25, -44.85 APE12-dist-in 10.3092 APE11-dist-out 6.2858 APE10-dist-out 9.0768 APE9-dist-in 3.7758 None None None XRAY 1.42 0.154 0.188 B 301.0 295.0 0 32 32 0 [[207, 497]] 1.0 6szm Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

Ligand: M2Z

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name