Ligand: M1O

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBtrans 3 75.0% 7U98B
DFGin None 1 25.0% 7U98A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 7U98B P00533 701 1005 1210.0 M1O:1101 Type1 Inactive DFGin 5.6086 16.6112 BLBtrans -140.13, -174.53 48.89, 57.71 -85.81, 131.72 167.62, 55.27 65.83, 6.33 out-out out 13.5772 Saltbr-out 13.5348 HRD-in -76.37, -57.65 78.87, -5.89 out-out-out SNCooo out-out ActLoopNT-out 6.9167 ActLoopCT-out TYR APEdihe_niiai APEdist_aaao APE10-dihe-none 999.0, 8.89 APE9-dihe-in -69.72, 140.24 APE8-dihe-in -81.34, 67.13 APE8-rot-na 31.34 APE67-dihe-in -70.75, -7.15 -60.08, -43.98 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 12.6718 APE9-dist-out 8.2301 T790M,V948R None None XRAY 3.42 0.216 0.244 B 331.0 293.0 12 30 18 12 [[712, 970]] 1.0 7u98 TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7U98C P00533 702 1007 1210.0 M1O:1101 Type1 Inactive DFGin 5.0841 16.3008 BLBtrans -131.03, -174.08 58.46, 35.85 -67.66, 147.46 158.98, 69.58 40.61, 29.57 out-out out 13.6113 Saltbr-out 12.985 HRD-in -71.79, -58.03 80.81, -14.3 out-out-out SNCooo out-out ActLoopNT-out 8.7043 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 128.85 APE8-dihe-in -70.24, 67.11 APE8-rot-na 29.02 APE67-dihe-in -75.38, -2.45 -60.79, -40.52 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.3021 T790M,V948R None None XRAY 3.42 0.216 0.244 C 331.0 286.0 20 30 16 14 [[712, 970]] 1.0 7u98 TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7U98D P00533 701 1007 1210.0 M1O:1101 Type1 Inactive DFGin 5.7338 16.4305 BLBtrans -133.75, -174.31 52.82, 34.09 -65.47, 149.8 160.31, 69.84 72.06, -122.62 out-out out 13.7188 Saltbr-out 13.8044 HRD-in -70.87, -55.75 80.84, -15.72 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 128.2 APE8-dihe-in -87.12, 65.67 APE8-rot-na 32.02 APE67-dihe-in -75.78, -0.75 -61.11, -41.8 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.5339 T790M,V948R None None XRAY 3.42 0.216 0.244 D 331.0 285.0 22 30 14 16 [[712, 970]] 1.0 7u98 TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7U98A P00533 701 1007 1210.0 M1O:1101 Type1 Inactive DFGin 5.2916 16.4611 None -131.78, -176.31 58.71, 37.78 -55.07, -79.17 157.63, 65.72 -77.42, -26.86 out-out out 13.9765 Saltbr-out 14.699 HRD-in -68.9, -54.72 82.24, -14.81 out-out-none SNCoon out-none ActLoopNT-out 7.1211 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 67.12 APE8-rot-na 30.49 APE67-dihe-in -75.19, -1.88 -59.47, -39.67 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 T790M,V948R None None XRAY 3.42 0.216 0.244 A 331.0 287.0 20 30 16 14 [[712, 970]] 1.0 7u98 TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

Ligand: M1O

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBtrans 3 75.0% 7U98B
DFGin None 1 25.0% 7U98A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 7U98B P00533 701 1005 1210.0 M1O:1101 Type1 Inactive DFGin 5.6086 16.6112 BLBtrans -140.13, -174.53 48.89, 57.71 -85.81, 131.72 167.62, 55.27 65.83, 6.33 out-out out 13.5772 Saltbr-out 13.5348 HRD-in -76.37, -57.65 78.87, -5.89 out-out-out SNCooo out-out ActLoopNT-out 6.9167 ActLoopCT-out TYR APEdihe_niiai APEdist_aaao APE10-dihe-none 999.0, 8.89 APE9-dihe-in -69.72, 140.24 APE8-dihe-in -81.34, 67.13 APE8-rot-na 31.34 APE67-dihe-in -70.75, -7.15 -60.08, -43.98 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 12.6718 APE9-dist-out 8.2301 T790M,V948R None None XRAY 3.42 0.216 0.244 B 331.0 293.0 12 30 18 12 [[712, 970]] 1.0 7u98 Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7U98C P00533 702 1007 1210.0 M1O:1101 Type1 Inactive DFGin 5.0841 16.3008 BLBtrans -131.03, -174.08 58.46, 35.85 -67.66, 147.46 158.98, 69.58 40.61, 29.57 out-out out 13.6113 Saltbr-out 12.985 HRD-in -71.79, -58.03 80.81, -14.3 out-out-out SNCooo out-out ActLoopNT-out 8.7043 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 128.85 APE8-dihe-in -70.24, 67.11 APE8-rot-na 29.02 APE67-dihe-in -75.38, -2.45 -60.79, -40.52 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.3021 T790M,V948R None None XRAY 3.42 0.216 0.244 C 331.0 286.0 20 30 16 14 [[712, 970]] 1.0 7u98 Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7U98D P00533 701 1007 1210.0 M1O:1101 Type1 Inactive DFGin 5.7338 16.4305 BLBtrans -133.75, -174.31 52.82, 34.09 -65.47, 149.8 160.31, 69.84 72.06, -122.62 out-out out 13.7188 Saltbr-out 13.8044 HRD-in -70.87, -55.75 80.84, -15.72 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 128.2 APE8-dihe-in -87.12, 65.67 APE8-rot-na 32.02 APE67-dihe-in -75.78, -0.75 -61.11, -41.8 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.5339 T790M,V948R None None XRAY 3.42 0.216 0.244 D 331.0 285.0 22 30 14 16 [[712, 970]] 1.0 7u98 Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7U98A P00533 701 1007 1210.0 M1O:1101 Type1 Inactive DFGin 5.2916 16.4611 None -131.78, -176.31 58.71, 37.78 -55.07, -79.17 157.63, 65.72 -77.42, -26.86 out-out out 13.9765 Saltbr-out 14.699 HRD-in -68.9, -54.72 82.24, -14.81 out-out-none SNCoon out-none ActLoopNT-out 7.1211 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 67.12 APE8-rot-na 30.49 APE67-dihe-in -75.19, -1.88 -59.47, -39.67 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 T790M,V948R None None XRAY 3.42 0.216 0.244 A 331.0 287.0 20 30 16 14 [[712, 970]] 1.0 7u98 Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

Ligand: M1O

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name