Ligand: LRT

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name

Ligand: LRT

Total number of chains: 3
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 66.7% 6SQ1A
DFGin ABAminus 1 33.3% 6Y2UA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AGC PRKACA KAPCA_CRIGR 6Y2UA P25321 1 351 351.0 LRT:60401 Type1 Inactive DFGin 6.3897 14.1273 ABAminus -116.87, -29.74 -101.42, 118.51 -125.0, 17.87 293.73, 84.27 -60.5, -32.85 in-in in 8.8178 Saltbr-in 2.7471 HRD-in -82.23, -56.84 69.37, 8.99 in-in-in SNCiii in-in ActLoopNT-in 2.9228 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -150.67, 161.61 APE9-dihe-na 116.23, -161.47 APE8-dihe-in -111.19, 132.56 APE8-rot-in 301.77 APE67-dihe-in -58.37, -26.58 -47.25, -49.31 APE12-dist-in 8.1796 APE11-dist-in 11.6373 APE10-dist-in 5.9769 APE9-dist-in 3.8833 None SEP11,TPO198,SEP339 SEP11,TPO198,SEP339 XRAY 1.93 0.187 0.222 A 353.0 351.0 0 25 25 0 [[44, 298]] 1.0 6y2u Cricetulus griseus AGC_PRKACA_CRIGR AGC 6.6e-95 323.2 1.0 260.0 260.0 184 185 186 188 190 73 92 96 164 166 165 167.0 221 209 204 203 202 201 200 199 198 122 cAMP-dependent protein kinase catalytic subunit alpha
AGC PRKACA KAPCA_CRIGR 6SQ1A P25321 14 351 351.0 LRT:60403 Type1 Active DFGin 6.2159 14.2505 BLAminus -121.79, 172.1 69.1, 85.08 -99.08, 24.56 277.81, 66.67 -63.84, -22.93 in-in in 8.6518 Saltbr-in 2.6996 HRD-in -89.13, -55.11 71.03, 9.14 in-in-in SNCiii in-in ActLoopNT-in 2.9507 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -159.84, 157.22 APE9-dihe-na 133.4, -154.71 APE8-dihe-in -125.36, 134.74 APE8-rot-in 298.73 APE67-dihe-in -64.25, -21.15 -48.42, -47.94 APE12-dist-in 7.9507 APE11-dist-in 11.2453 APE10-dist-in 5.8092 APE9-dist-in 3.9436 None SEP140,TPO198,SEP339 SEP140,TPO198,SEP339 XRAY 1.49 0.144 0.177 A 353.0 338.0 0 25 25 0 [[44, 298]] 1.0 6sq1 Cricetulus griseus AGC_PRKACA_CRIGR AGC 6.6e-95 323.2 1.0 260.0 260.0 184 185 186 188 190 73 92 96 164 166 165 167.0 221 209 204 203 202 201 200 199 198 122 cAMP-dependent protein kinase catalytic subunit alpha
AGC PRKACA KAPCA_CRIGR 6YNTA P25321 6 351 351.0 LRT:60405 Type1 Active DFGin 6.0242 14.3498 BLAminus -127.88, -176.71 61.66, 78.46 -90.86, 25.34 272.68, 60.44 -59.78, -24.31 in-in in 9.06 Saltbr-in 2.6983 HRD-in -92.67, -53.37 74.33, 11.71 in-in-in SNCiii in-in ActLoopNT-in 2.9262 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -158.24, 160.78 APE9-dihe-na 130.38, -159.85 APE8-dihe-in -120.86, 135.61 APE8-rot-in 299.16 APE67-dihe-in -60.2, -23.36 -47.55, -51.43 APE12-dist-in 8.1139 APE11-dist-in 11.3697 APE10-dist-in 5.8425 APE9-dist-in 3.5589 None SEP11,TPO198,SEP339 SEP11,TPO198,SEP339 XRAY 1.52 0.171 0.191 A 353.0 346.0 0 25 25 0 [[44, 298]] 1.0 6ynt Cricetulus griseus AGC_PRKACA_CRIGR AGC 6.6e-95 323.2 1.0 260.0 260.0 184 185 186 188 190 73 92 96 164 166 165 167.0 221 209 204 203 202 201 200 199 198 122 cAMP-dependent protein kinase catalytic subunit alpha

Ligand: LRT

Total number of chains: 3
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 66.7% 6SQ1A
DFGin ABAminus 1 33.3% 6Y2UA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AGC PRKACA KAPCA_CRIGR 6Y2UA P25321 1 351 351.0 LRT:60401 Type1 Inactive DFGin 6.3897 14.1273 ABAminus -116.87, -29.74 -101.42, 118.51 -125.0, 17.87 293.73, 84.27 -60.5, -32.85 in-in in 8.8178 Saltbr-in 2.7471 HRD-in -82.23, -56.84 69.37, 8.99 in-in-in SNCiii in-in ActLoopNT-in 2.9228 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -150.67, 161.61 APE9-dihe-na 116.23, -161.47 APE8-dihe-in -111.19, 132.56 APE8-rot-in 301.77 APE67-dihe-in -58.37, -26.58 -47.25, -49.31 APE12-dist-in 8.1796 APE11-dist-in 11.6373 APE10-dist-in 5.9769 APE9-dist-in 3.8833 None SEP11,TPO198,SEP339 SEP11,TPO198,SEP339 XRAY 1.93 0.187 0.222 A 353.0 351.0 0 25 25 0 [[44, 298]] 1.0 6y2u Cricetulus griseus AGC_PRKACA_CRIGR AGC 6.6e-95 323.2 1.0 260.0 260.0 184 185 186 188 190 73 92 96 164 166 165 167.0 221 209 204 203 202 201 200 199 198 122 cAMP-dependent protein kinase catalytic subunit alpha
AGC PRKACA KAPCA_CRIGR 6SQ1A P25321 14 351 351.0 LRT:60403 Type1 Active DFGin 6.2159 14.2505 BLAminus -121.79, 172.1 69.1, 85.08 -99.08, 24.56 277.81, 66.67 -63.84, -22.93 in-in in 8.6518 Saltbr-in 2.6996 HRD-in -89.13, -55.11 71.03, 9.14 in-in-in SNCiii in-in ActLoopNT-in 2.9507 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -159.84, 157.22 APE9-dihe-na 133.4, -154.71 APE8-dihe-in -125.36, 134.74 APE8-rot-in 298.73 APE67-dihe-in -64.25, -21.15 -48.42, -47.94 APE12-dist-in 7.9507 APE11-dist-in 11.2453 APE10-dist-in 5.8092 APE9-dist-in 3.9436 None SEP140,TPO198,SEP339 SEP140,TPO198,SEP339 XRAY 1.49 0.144 0.177 A 353.0 338.0 0 25 25 0 [[44, 298]] 1.0 6sq1 Cricetulus griseus AGC_PRKACA_CRIGR AGC 6.6e-95 323.2 1.0 260.0 260.0 184 185 186 188 190 73 92 96 164 166 165 167.0 221 209 204 203 202 201 200 199 198 122 cAMP-dependent protein kinase catalytic subunit alpha
AGC PRKACA KAPCA_CRIGR 6YNTA P25321 6 351 351.0 LRT:60405 Type1 Active DFGin 6.0242 14.3498 BLAminus -127.88, -176.71 61.66, 78.46 -90.86, 25.34 272.68, 60.44 -59.78, -24.31 in-in in 9.06 Saltbr-in 2.6983 HRD-in -92.67, -53.37 74.33, 11.71 in-in-in SNCiii in-in ActLoopNT-in 2.9262 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -158.24, 160.78 APE9-dihe-na 130.38, -159.85 APE8-dihe-in -120.86, 135.61 APE8-rot-in 299.16 APE67-dihe-in -60.2, -23.36 -47.55, -51.43 APE12-dist-in 8.1139 APE11-dist-in 11.3697 APE10-dist-in 5.8425 APE9-dist-in 3.5589 None SEP11,TPO198,SEP339 SEP11,TPO198,SEP339 XRAY 1.52 0.171 0.191 A 353.0 346.0 0 25 25 0 [[44, 298]] 1.0 6ynt Cricetulus griseus AGC_PRKACA_CRIGR AGC 6.6e-95 323.2 1.0 260.0 260.0 184 185 186 188 190 73 92 96 164 166 165 167.0 221 209 204 203 202 201 200 199 198 122 cAMP-dependent protein kinase catalytic subunit alpha