Ligand: LDN

Total number of chains: 32
Active chains: 2
Total number of genes: 3
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 32 100.0% 3Q4UA
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Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TKL ACVR1 ACVR1_HUMAN 3Q4UA 1.82 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 202 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 3Q4UB 1.82 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 201 - 498 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 3Q4UC 1.82 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 204 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 3Q4UD 1.82 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 201 - 499 0 None Q207D Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 6UNSA 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 204 - 496 0 None K492A,K493A Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 6UNSB 2.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 204 - 496 0 None K492A,K493A Activin receptor type-1
TKL ACVRL1 ACVL1_HUMAN 3MY0A 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 493 0 None None Activin receptor type-1-like
TKL ACVRL1 ACVL1_HUMAN 3MY0B 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 494 0 None None Activin receptor type-1-like
TKL ACVRL1 ACVL1_HUMAN 3MY0C 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 492 0 None None Activin receptor type-1-like
TKL ACVRL1 ACVL1_HUMAN 3MY0D 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 491 0 None None Activin receptor type-1-like
TKL ACVRL1 ACVL1_HUMAN 3MY0E 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 493 0 None None Activin receptor type-1-like
TKL ACVRL1 ACVL1_HUMAN 3MY0F 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 493 0 None None Activin receptor type-1-like
TKL ACVRL1 ACVL1_HUMAN 3MY0G 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 493 0 None None Activin receptor type-1-like
TKL ACVRL1 ACVL1_HUMAN 3MY0H 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 492 0 None None Activin receptor type-1-like
TKL ACVRL1 ACVL1_HUMAN 3MY0I 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 493 0 None None Activin receptor type-1-like
TKL ACVRL1 ACVL1_HUMAN 3MY0J 2.65 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aannn APEdist_nnnn LDN Type1 200 - 493 0 None None Activin receptor type-1-like
TKL ACVRL1 ACVL1_HUMAN 3MY0K 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 492 0 None None Activin receptor type-1-like
TKL ACVRL1 ACVL1_HUMAN 3MY0L 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 493 0 None None Activin receptor type-1-like
TKL ACVRL1 ACVL1_HUMAN 3MY0M 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 494 0 None None Activin receptor type-1-like
TKL ACVRL1 ACVL1_HUMAN 3MY0N 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 493 0 None None Activin receptor type-1-like
TKL ACVRL1 ACVL1_HUMAN 3MY0O 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 490 0 None None Activin receptor type-1-like
TKL ACVRL1 ACVL1_HUMAN 3MY0P 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 493 0 None None Activin receptor type-1-like
TKL ACVRL1 ACVL1_HUMAN 3MY0Q 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 493 0 None None Activin receptor type-1-like
TKL ACVRL1 ACVL1_HUMAN 3MY0R 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 493 0 None None Activin receptor type-1-like
TKL ACVRL1 ACVL1_HUMAN 3MY0S 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 492 0 None None Activin receptor type-1-like
TKL ACVRL1 ACVL1_HUMAN 3MY0T 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 492 0 None None Activin receptor type-1-like
TKL ACVRL1 ACVL1_HUMAN 3MY0U 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 493 0 None None Activin receptor type-1-like
TKL ACVRL1 ACVL1_HUMAN 3MY0V 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 493 0 None None Activin receptor type-1-like
TKL ACVRL1 ACVL1_HUMAN 3MY0W 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 493 0 None None Activin receptor type-1-like
TKL ACVRL1 ACVL1_HUMAN 3MY0X 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 488 0 None None Activin receptor type-1-like
TKL BMPR1B BMR1B_HUMAN 3MDYA 2.05 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii LDN Type1 174 - 502 0 None None Bone morphogenetic protein receptor type-1B
TKL BMPR1B BMR1B_HUMAN 3MDYC 2.05 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii LDN Type1 174 - 500 0 None None Bone morphogenetic protein receptor type-1B

Ligand: LDN

Total number of chains: 32
Active chains: 2
Total number of genes: 3
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 32 100.0% 3Q4UA
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TKL ACVR1 ACVR1_HUMAN 3Q4UA 1.82 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 202 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 3Q4UB 1.82 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 201 - 498 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 3Q4UC 1.82 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 204 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 3Q4UD 1.82 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 201 - 499 0 None Q207D Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 6UNSA 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 204 - 496 0 None K492A,K493A Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 6UNSB 2.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 204 - 496 0 None K492A,K493A Activin receptor type-1 Homo sapiens
TKL ACVRL1 ACVL1_HUMAN 3MY0A 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 493 0 None None Activin receptor type-1-like Homo sapiens
TKL ACVRL1 ACVL1_HUMAN 3MY0B 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 494 0 None None Activin receptor type-1-like Homo sapiens
TKL ACVRL1 ACVL1_HUMAN 3MY0C 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 492 0 None None Activin receptor type-1-like Homo sapiens
TKL ACVRL1 ACVL1_HUMAN 3MY0D 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 491 0 None None Activin receptor type-1-like Homo sapiens
TKL ACVRL1 ACVL1_HUMAN 3MY0E 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 493 0 None None Activin receptor type-1-like Homo sapiens
TKL ACVRL1 ACVL1_HUMAN 3MY0F 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 493 0 None None Activin receptor type-1-like Homo sapiens
TKL ACVRL1 ACVL1_HUMAN 3MY0G 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 493 0 None None Activin receptor type-1-like Homo sapiens
TKL ACVRL1 ACVL1_HUMAN 3MY0H 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 492 0 None None Activin receptor type-1-like Homo sapiens
TKL ACVRL1 ACVL1_HUMAN 3MY0I 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 493 0 None None Activin receptor type-1-like Homo sapiens
TKL ACVRL1 ACVL1_HUMAN 3MY0J 2.65 Inactive DFGin‑BLAminus in-out in-none nonTYR APEdihe_aannn APEdist_nnnn LDN Type1 200 - 493 0 None None Activin receptor type-1-like Homo sapiens
TKL ACVRL1 ACVL1_HUMAN 3MY0K 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 492 0 None None Activin receptor type-1-like Homo sapiens
TKL ACVRL1 ACVL1_HUMAN 3MY0L 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 493 0 None None Activin receptor type-1-like Homo sapiens
TKL ACVRL1 ACVL1_HUMAN 3MY0M 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 494 0 None None Activin receptor type-1-like Homo sapiens
TKL ACVRL1 ACVL1_HUMAN 3MY0N 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 493 0 None None Activin receptor type-1-like Homo sapiens
TKL ACVRL1 ACVL1_HUMAN 3MY0O 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 490 0 None None Activin receptor type-1-like Homo sapiens
TKL ACVRL1 ACVL1_HUMAN 3MY0P 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 493 0 None None Activin receptor type-1-like Homo sapiens
TKL ACVRL1 ACVL1_HUMAN 3MY0Q 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 493 0 None None Activin receptor type-1-like Homo sapiens
TKL ACVRL1 ACVL1_HUMAN 3MY0R 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 493 0 None None Activin receptor type-1-like Homo sapiens
TKL ACVRL1 ACVL1_HUMAN 3MY0S 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 492 0 None None Activin receptor type-1-like Homo sapiens
TKL ACVRL1 ACVL1_HUMAN 3MY0T 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 492 0 None None Activin receptor type-1-like Homo sapiens
TKL ACVRL1 ACVL1_HUMAN 3MY0U 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 493 0 None None Activin receptor type-1-like Homo sapiens
TKL ACVRL1 ACVL1_HUMAN 3MY0V 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 493 0 None None Activin receptor type-1-like Homo sapiens
TKL ACVRL1 ACVL1_HUMAN 3MY0W 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 493 0 None None Activin receptor type-1-like Homo sapiens
TKL ACVRL1 ACVL1_HUMAN 3MY0X 2.65 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi LDN Type1 195 - 488 0 None None Activin receptor type-1-like Homo sapiens
TKL BMPR1B BMR1B_HUMAN 3MDYA 2.05 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii LDN Type1 174 - 502 0 None None Bone morphogenetic protein receptor type-1B Homo sapiens
TKL BMPR1B BMR1B_HUMAN 3MDYC 2.05 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii LDN Type1 174 - 500 0 None None Bone morphogenetic protein receptor type-1B Homo sapiens

Ligand: LDN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Advanced page

Hover over column headers for tooltip help

Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism