Ligand: JAK

Total number of chains: 5
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 5 100.0% 4F09A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR JAK1-2 JAK1_HUMAN 4EHZA 2.174 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai JAK Type1 858 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4EHZB 2.174 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai JAK Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4EHZC 2.174 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai JAK Type1 866 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4EHZD 2.174 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai JAK Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK2-2 JAK2_HUMAN 4F09A 2.4 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai JAK Type1 843 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2

Ligand: JAK

Total number of chains: 5
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 5 100.0% 4F09A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR JAK1-2 JAK1_HUMAN 4EHZA 2.174 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai JAK Type1 858 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 4EHZB 2.174 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai JAK Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 4EHZC 2.174 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai JAK Type1 866 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 4EHZD 2.174 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai JAK Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 4F09A 2.4 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai JAK Type1 843 - 1132 0 PTR1007,PTR1008 None Tyrosine-protein kinase JAK2 Homo sapiens

Ligand: JAK

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism