Ligand: J2M

Total number of chains: 1
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 100.0% 5QIKA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TKL TGFBR1 TGFR1_HUMAN 5QIKA 1.58 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii J2M Type1 200 - 499 0 None T204D TGF-beta receptor type-1

Ligand: J2M

Total number of chains: 1
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 100.0% 5QIKA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TKL TGFBR1 TGFR1_HUMAN 5QIKA 1.58 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii J2M Type1 200 - 499 0 None T204D TGF-beta receptor type-1 Homo sapiens

Ligand: J2M

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism