Ligand: IE0

Total number of chains: 2
Active chains: 1
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 9FQSA
DFGout None 1 50.0% 8PYLAAA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 9FQSA P00533 701 1019 1210.0 A1IE0:61103 Type1.5_Back Active DFGin 6.134 14.192 BLAminus -132.91, -178.24 67.27, 86.84 -99.9, 25.54 296.52, 82.26 -59.0, -36.29 in-in in 8.617 Saltbr-in 2.89 HRD-in -69.4, -45.72 68.58, -3.7 in-in-in SNCiii in-in ActLoopNT-in 2.859 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -71.39, 137.92 APE9-dihe-in -140.19, 151.4 APE8-dihe-in -80.21, 88.89 APE8-rot-na 33.48 APE67-dihe-in -69.87, -7.88 -52.66, -46.03 APE12-dist-na 12.19 APE11-dist-na 9.316 APE10-dist-na 9.94 APE9-dist-in 6.4 V948R None None XRAY 1.783 0.199 0.237 A 338 302 5 0 0 0 [[712, 970]] 1.0 9fqs TYR_EGFR_HUMAN TYR 1.3e-85 292.9 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR IGF1R IGF1R_HUMAN 8PYLAAA P08069 986 1270 1367.0 IE0:1301 Type2 Inactive DFGout 17.49 8.802 None -135.7, -153.05 -170.07, 104.78 -81.37, -21.74 213.38, 146.3 99.88, -176.88 out-out out 10.258 Saltbr-out 5.022 HRD-in -75.5, -46.79 77.95, -4.93 out-out-in SNCooi out-in ActLoopNT-out 18.194 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -61.72, 135.11 APE9-dihe-in -129.69, 131.01 APE8-dihe-in -77.6, 68.98 APE8-rot-na 32.9 APE67-dihe-in -67.64, -16.63 -60.37, -36.74 APE12-dist-na 13.769 APE11-dist-na 9.55 APE10-dist-na 5.581 APE9-dist-in 7.367 None None None XRAY 2.93 0.191 0.249 AAA 321 277 8 0 0 0 [[999, 1268]] 1.0 8pyl TYR_IGF1R_HUMAN TYR 2.3e-95 324.8 1 260 260 1152 1153 1154 1156 1158 1033 1050 1054 1132 1134 1133 1135 1194 1182 1177 1176 1175 1174 1173 1172 1171 1080 Insulin-like growth factor 1 receptor

Ligand: IE0

Total number of chains: 2
Active chains: 1
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 9FQSA
DFGout None 1 50.0% 8PYLAAA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 9FQSA P00533 701 1019 1210.0 A1IE0:61103 Type1.5_Back Active DFGin 6.134 14.192 BLAminus -132.91, -178.24 67.27, 86.84 -99.9, 25.54 296.52, 82.26 -59.0, -36.29 in-in in 8.617 Saltbr-in 2.89 HRD-in -69.4, -45.72 68.58, -3.7 in-in-in SNCiii in-in ActLoopNT-in 2.859 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -71.39, 137.92 APE9-dihe-in -140.19, 151.4 APE8-dihe-in -80.21, 88.89 APE8-rot-na 33.48 APE67-dihe-in -69.87, -7.88 -52.66, -46.03 APE12-dist-na 12.19 APE11-dist-na 9.316 APE10-dist-na 9.94 APE9-dist-in 6.4 V948R None None XRAY 1.783 0.199 0.237 A 338 302 5 0 0 0 [[712, 970]] 1.0 9fqs Homo sapiens TYR_EGFR_HUMAN TYR 1.3e-85 292.9 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR IGF1R IGF1R_HUMAN 8PYLAAA P08069 986 1270 1367.0 IE0:1301 Type2 Inactive DFGout 17.49 8.802 None -135.7, -153.05 -170.07, 104.78 -81.37, -21.74 213.38, 146.3 99.88, -176.88 out-out out 10.258 Saltbr-out 5.022 HRD-in -75.5, -46.79 77.95, -4.93 out-out-in SNCooi out-in ActLoopNT-out 18.194 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -61.72, 135.11 APE9-dihe-in -129.69, 131.01 APE8-dihe-in -77.6, 68.98 APE8-rot-na 32.9 APE67-dihe-in -67.64, -16.63 -60.37, -36.74 APE12-dist-na 13.769 APE11-dist-na 9.55 APE10-dist-na 5.581 APE9-dist-in 7.367 None None None XRAY 2.93 0.191 0.249 AAA 321 277 8 0 0 0 [[999, 1268]] 1.0 8pyl Homo sapiens TYR_IGF1R_HUMAN TYR 2.3e-95 324.8 1 260 260 1152 1153 1154 1156 1158 1033 1050 1054 1132 1134 1133 1135 1194 1182 1177 1176 1175 1174 1173 1172 1171 1080 Insulin-like growth factor 1 receptor

Ligand: IE0

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name