Ligand: H5R

Total number of chains: 3
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 66.7% 8S85B
DFGin BLAminus 1 33.3% 7DG4A
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CMGC DYRK2 DYRK2_HUMAN 7DG4A 2.58 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii H5R Type1 215 - 538 0 PTR382,SEP458 None Dual specificity tyrosine-phosphorylation-regulated kinase 2
TYR JAK1-2 JAK1_HUMAN 8S85A 1.75 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai A1H5R Type1 854 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 8S85B 1.75 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai A1H5R Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1

Ligand: H5R

Total number of chains: 3
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 66.7% 8S85B
DFGin BLAminus 1 33.3% 7DG4A
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC DYRK2 DYRK2_HUMAN 7DG4A 2.58 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii H5R Type1 215 - 538 0 PTR382,SEP458 None Dual specificity tyrosine-phosphorylation-regulated kinase 2 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 8S85A 1.75 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai A1H5R Type1 854 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR JAK1-2 JAK1_HUMAN 8S85B 1.75 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai A1H5R Type1 865 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens

Ligand: H5R

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Advanced page

Hover over column headers for tooltip help

Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism