Ligand: H1N

Total number of chains: 3
Active chains: 1
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 4QMTA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CAMK CAMKK1 KKCC1_HUMAN 6CCFA Q8N5S9 124 411 505.0 H1N:60501 Type1 Inactive DFGin 6.9822 14.2827 BLAminus -129.63, 176.21 62.09, 90.97 -101.79, 18.55 285.4, 75.97 -64.26, -22.76 out-out out 14.0584 Saltbr-out 12.4299 HRD-in -79.89, -51.68 75.56, 1.6 out-in-in SNCoii in-in ActLoopNT-in 2.9478 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -156.85, 153.62 APE9-dihe-na 115.71, -151.61 APE8-dihe-in -106.82, 124.89 APE8-rot-in 306.74 APE67-dihe-in -69.72, -15.74 -42.83, -46.56 APE12-dist-in 10.017 APE11-dist-in 10.5615 APE10-dist-in 5.119 APE9-dist-in 3.4454 None None None XRAY 2.1 0.212 0.244 A 290.0 259.0 29 28 28 0 [[128, 409]] 1.0 6ccf CAMK_CAMKK1_HUMAN CAMK 6.6e-70 241.4 1.0 256.0 256.0 292 293 294 296 298 157 199 203 272 274 273 275.0 335 320 315 314 313 312 311 310 309 231 Calcium/calmodulin-dependent protein kinase kinase 1
CAMK CAMKK1 KKCC1_HUMAN 6CCFB Q8N5S9 124 411 505.0 H1N:60501 Type1 Inactive DFGin 7.2731 14.0653 BLAminus -126.55, 172.15 65.89, 86.71 -96.71, 27.86 289.91, 81.79 -69.35, -26.21 out-out out 13.6926 Saltbr-out 11.7365 HRD-in -74.19, -48.51 77.63, 6.18 out-in-in SNCoii in-in ActLoopNT-in 3.019 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -168.63, 140.92 APE9-dihe-na 123.47, -148.43 APE8-dihe-in -109.58, 128.52 APE8-rot-in 304.9 APE67-dihe-in -58.4, -24.99 -49.75, -46.8 APE12-dist-in 10.77 APE11-dist-in 10.6482 APE10-dist-in 5.1899 APE9-dist-in 3.4462 None None None XRAY 2.1 0.212 0.244 B 290.0 261.0 27 28 28 0 [[128, 409]] 1.0 6ccf CAMK_CAMKK1_HUMAN CAMK 6.6e-70 241.4 1.0 256.0 256.0 292 293 294 296 298 157 199 203 272 274 273 275.0 335 320 315 314 313 312 311 310 309 231 Calcium/calmodulin-dependent protein kinase kinase 1
STE STK24 STK24_HUMAN 4QMTA Q9Y6E0 27 311 443.0 H1N:60401 Type1 Active DFGin 6.6921 14.5096 BLAminus -135.76, 169.96 68.22, 92.24 -111.29, 19.37 290.68, 93.58 -60.25, -31.42 in-in in 8.5862 Saltbr-in 2.8056 HRD-in -69.73, -51.28 73.34, 0.05 in-in-in SNCiii in-in ActLoopNT-in 2.8223 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -143.38, 158.58 APE9-dihe-na 127.76, -164.52 APE8-dihe-in -119.79, 120.1 APE8-rot-in 305.04 APE67-dihe-in -61.83, -25.4 -41.8, -49.43 APE12-dist-in 8.1078 APE11-dist-in 10.9221 APE10-dist-in 5.1766 APE9-dist-in 3.3349 None TPO190 TPO190 XRAY 1.5 0.15 0.185 A 310.0 285.0 0 28 28 0 [[36, 286]] 1.0 4qmt STE_STK24_HUMAN STE 3.9e-100 340.4 1.0 257.0 257.0 173 174 175 177 179 65 82 86 153 155 154 156.0 213 201 196 195 194 193 192 191 190 112 Serine/threonine-protein kinase 24

Ligand: H1N

Total number of chains: 5
Active chains: 1
Total number of genes: 3
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 60.0% 4QMTA
DFGin ABAminus 2 40.0% 2BFYA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CAMK CAMKK1 KKCC1_HUMAN 6CCFA Q8N5S9 124 411 505.0 H1N:60501 Type1 Inactive DFGin 6.9822 14.2827 BLAminus -129.63, 176.21 62.09, 90.97 -101.79, 18.55 285.4, 75.97 -64.26, -22.76 out-out out 14.0584 Saltbr-out 12.4299 HRD-in -79.89, -51.68 75.56, 1.6 out-in-in SNCoii in-in ActLoopNT-in 2.9478 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -156.85, 153.62 APE9-dihe-na 115.71, -151.61 APE8-dihe-in -106.82, 124.89 APE8-rot-in 306.74 APE67-dihe-in -69.72, -15.74 -42.83, -46.56 APE12-dist-in 10.017 APE11-dist-in 10.5615 APE10-dist-in 5.119 APE9-dist-in 3.4454 None None None XRAY 2.1 0.212 0.244 A 290.0 259.0 29 28 28 0 [[128, 409]] 1.0 6ccf Homo sapiens CAMK_CAMKK1_HUMAN CAMK 6.6e-70 241.4 1.0 256.0 256.0 292 293 294 296 298 157 199 203 272 274 273 275.0 335 320 315 314 313 312 311 310 309 231 Calcium/calmodulin-dependent protein kinase kinase 1
CAMK CAMKK1 KKCC1_HUMAN 6CCFB Q8N5S9 124 411 505.0 H1N:60501 Type1 Inactive DFGin 7.2731 14.0653 BLAminus -126.55, 172.15 65.89, 86.71 -96.71, 27.86 289.91, 81.79 -69.35, -26.21 out-out out 13.6926 Saltbr-out 11.7365 HRD-in -74.19, -48.51 77.63, 6.18 out-in-in SNCoii in-in ActLoopNT-in 3.019 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -168.63, 140.92 APE9-dihe-na 123.47, -148.43 APE8-dihe-in -109.58, 128.52 APE8-rot-in 304.9 APE67-dihe-in -58.4, -24.99 -49.75, -46.8 APE12-dist-in 10.77 APE11-dist-in 10.6482 APE10-dist-in 5.1899 APE9-dist-in 3.4462 None None None XRAY 2.1 0.212 0.244 B 290.0 261.0 27 28 28 0 [[128, 409]] 1.0 6ccf Homo sapiens CAMK_CAMKK1_HUMAN CAMK 6.6e-70 241.4 1.0 256.0 256.0 292 293 294 296 298 157 199 203 272 274 273 275.0 335 320 315 314 313 312 311 310 309 231 Calcium/calmodulin-dependent protein kinase kinase 1
STE STK24 STK24_HUMAN 4QMTA Q9Y6E0 27 311 443.0 H1N:60401 Type1 Active DFGin 6.6921 14.5096 BLAminus -135.76, 169.96 68.22, 92.24 -111.29, 19.37 290.68, 93.58 -60.25, -31.42 in-in in 8.5862 Saltbr-in 2.8056 HRD-in -69.73, -51.28 73.34, 0.05 in-in-in SNCiii in-in ActLoopNT-in 2.8223 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -143.38, 158.58 APE9-dihe-na 127.76, -164.52 APE8-dihe-in -119.79, 120.1 APE8-rot-in 305.04 APE67-dihe-in -61.83, -25.4 -41.8, -49.43 APE12-dist-in 8.1078 APE11-dist-in 10.9221 APE10-dist-in 5.1766 APE9-dist-in 3.3349 None TPO190 TPO190 XRAY 1.5 0.15 0.185 A 310.0 285.0 0 28 28 0 [[36, 286]] 1.0 4qmt Homo sapiens STE_STK24_HUMAN STE 3.9e-100 340.4 1.0 257.0 257.0 173 174 175 177 179 65 82 86 153 155 154 156.0 213 201 196 195 194 193 192 191 190 112 Serine/threonine-protein kinase 24
CAMK AURKBA AUKBA_XENLA 2BFYA Q6DE08 86 357 361.0 H1N:1357 Type1 Inactive DFGin 5.5341 15.7092 ABAminus -116.84, -1.88 -135.6, 140.82 -132.52, 30.57 278.95, 83.35 -56.9, -28.81 out-out out 10.5764 Saltbr-out 3.9653 HRD-in -79.01, -51.98 70.46, 4.19 out-in-in SNCoii in-in ActLoopNT-in 2.919 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -152.04, 167.81 APE9-dihe-na 113.75, -150.39 APE8-dihe-in -125.82, 135.68 APE8-rot-in 312.13 APE67-dihe-in -68.48, -12.78 -29.46, -62.69 APE12-dist-in 8.2152 APE11-dist-in 10.912 APE10-dist-in 5.3849 APE9-dist-in 3.6773 G96V TPO248 TPO248 XRAY 1.8 0.203 0.226 A 284.0 272.0 0 26 26 0 [[93, 343]] 1.0 2bfy Xenopus laevis CAMK_AURKBA_XENLA CAMK 5.9e-77 264.4 1.0 256.0 256.0 233 234 235 237 239 122 141 145 213 215 214 216.0 271 259 254 253 252 251 250 249 248 171 Aurora kinase B-A
CAMK AURKBA AUKBA_XENLA 2BFYB Q6DE08 78 357 361.0 H1N:1357 Type1 Inactive DFGin 5.5272 15.8785 ABAminus -115.69, -5.46 -135.16, 135.85 -127.64, 30.68 282.8, 80.72 -58.12, -29.16 out-out out 10.9349 Saltbr-out 5.5747 HRD-in -77.36, -51.18 70.55, 1.06 out-in-in SNCoii in-in ActLoopNT-in 2.9019 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -158.63, 164.67 APE9-dihe-na 131.32, -159.09 APE8-dihe-in -135.77, 136.74 APE8-rot-in 298.0 APE67-dihe-in -65.1, -17.6 -34.73, -62.41 APE12-dist-in 7.8397 APE11-dist-in 10.6173 APE10-dist-in 5.177 APE9-dist-in 3.5853 G96V TPO248 TPO248 XRAY 1.8 0.203 0.226 B 284.0 280.0 0 26 26 0 [[93, 343]] 1.0 2bfy Xenopus laevis CAMK_AURKBA_XENLA CAMK 5.9e-77 264.4 1.0 256.0 256.0 233 234 235 237 239 122 141 145 213 215 214 216.0 271 259 254 253 252 251 250 249 248 171 Aurora kinase B-A

Ligand: H1N

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 2BFYA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CAMK AURKBA AUKBA_XENLA 2BFYA Q6DE08 86 357 361.0 H1N:1357 Type1 Inactive DFGin 5.5341 15.7092 ABAminus -116.84, -1.88 -135.6, 140.82 -132.52, 30.57 278.95, 83.35 -56.9, -28.81 out-out out 10.5764 Saltbr-out 3.9653 HRD-in -79.01, -51.98 70.46, 4.19 out-in-in SNCoii in-in ActLoopNT-in 2.919 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -152.04, 167.81 APE9-dihe-na 113.75, -150.39 APE8-dihe-in -125.82, 135.68 APE8-rot-in 312.13 APE67-dihe-in -68.48, -12.78 -29.46, -62.69 APE12-dist-in 8.2152 APE11-dist-in 10.912 APE10-dist-in 5.3849 APE9-dist-in 3.6773 G96V TPO248 TPO248 XRAY 1.8 0.203 0.226 A 284.0 272.0 0 26 26 0 [[93, 343]] 1.0 2bfy Xenopus laevis CAMK_AURKBA_XENLA CAMK 5.9e-77 264.4 1.0 256.0 256.0 233 234 235 237 239 122 141 145 213 215 214 216.0 271 259 254 253 252 251 250 249 248 171 Aurora kinase B-A
CAMK AURKBA AUKBA_XENLA 2BFYB Q6DE08 78 357 361.0 H1N:1357 Type1 Inactive DFGin 5.5272 15.8785 ABAminus -115.69, -5.46 -135.16, 135.85 -127.64, 30.68 282.8, 80.72 -58.12, -29.16 out-out out 10.9349 Saltbr-out 5.5747 HRD-in -77.36, -51.18 70.55, 1.06 out-in-in SNCoii in-in ActLoopNT-in 2.9019 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -158.63, 164.67 APE9-dihe-na 131.32, -159.09 APE8-dihe-in -135.77, 136.74 APE8-rot-in 298.0 APE67-dihe-in -65.1, -17.6 -34.73, -62.41 APE12-dist-in 7.8397 APE11-dist-in 10.6173 APE10-dist-in 5.177 APE9-dist-in 3.5853 G96V TPO248 TPO248 XRAY 1.8 0.203 0.226 B 284.0 280.0 0 26 26 0 [[93, 343]] 1.0 2bfy Xenopus laevis CAMK_AURKBA_XENLA CAMK 5.9e-77 264.4 1.0 256.0 256.0 233 234 235 237 239 122 141 145 213 215 214 216.0 271 259 254 253 252 251 250 249 248 171 Aurora kinase B-A