Ligand: GE5

Total number of chains: 3
Active chains: 2
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 66.7% 6HMRA
DFGinter None 1 33.3% 6HWUA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CK1 CSNK1D KC1D_HUMAN 6HMRA P48730 7 294 415.0 GE5:60301 Type1 Active DFGin 5.9016 14.8263 BLAminus -129.77, 165.39 78.39, 101.15 -107.5, 20.0 293.32, 102.36 -64.81, -25.32 in-in in 8.2845 Saltbr-in 2.7492 HRD-in -83.07, -49.96 76.13, 7.49 in-in-in SNCiii in-in ActLoopNT-in 2.8245 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -105.61, 123.18 APE9-dihe-na 112.73, -152.95 APE8-dihe-in -99.78, 125.38 APE8-rot-in 305.84 APE67-dihe-in -55.81, -38.54 -61.27, -36.97 APE12-dist-in 12.6253 APE11-dist-in 12.3101 APE10-dist-in 6.7702 APE9-dist-in 3.9726 None None None XRAY 1.782 0.176 0.199 A 314.0 287.0 1 35 35 0 [[9, 275]] 1.0 6hmr CK1_CSNK1D_HUMAN CK1 1.9e-122 413.6 1.0 262.0 262.0 148 149 150 152 154 38 52 56 125 127 126 128.0 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
CK1 CSNK1D KC1D_HUMAN 6HMRB P48730 1 293 415.0 GE5:60301 Type1 Active DFGin 5.728 14.8214 BLAminus -132.18, 166.65 79.25, 99.25 -107.58, 20.5 292.42, 101.79 -65.16, -22.71 in-in in 8.1726 Saltbr-in 2.6324 HRD-in -83.94, -50.09 75.09, 8.55 in-in-in SNCiii in-in ActLoopNT-in 2.8028 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -95.7, -50.27 APE9-dihe-na -84.81, -142.78 APE8-dihe-in -93.52, 127.66 APE8-rot-in 306.5 APE67-dihe-in -55.61, -39.37 -59.1, -37.12 APE12-dist-in 12.085 APE11-dist-in 11.8293 APE10-dist-in 6.0284 APE9-dist-in 3.9267 None None None XRAY 1.782 0.176 0.199 B 314.0 279.0 14 35 35 0 [[9, 275]] 1.0 6hmr CK1_CSNK1D_HUMAN CK1 1.9e-122 413.6 1.0 262.0 262.0 148 149 150 152 154 38 52 56 125 127 126 128.0 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
CMGC MAPK14 MK14_HUMAN 6HWUA Q16539 5 353 360.0 GE5:404 Type1 Inactive DFGinter 9.5901 8.9682 None -118.08, 168.42 -117.72, 42.58 -170.41, 161.53 57.41, 87.05 -97.74, 161.01 in-in in 9.4576 Saltbr-in 2.9264 HRD-in -69.49, -51.73 75.06, -4.67 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_nnoo APE10-dihe-na 999.0, 73.5 APE9-dihe-na -65.73, 137.2 APE8-dihe-out -60.1, -34.07 APE8-rot-in 274.51 APE67-dihe-in -66.54, -24.29 -62.93, -25.28 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 11.2073 APE9-dist-out 11.5529 None None None XRAY 2.3 0.193 0.247 A 362.0 333.0 16 25 14 11 [[24, 308]] 1.0 6hwu CMGC_MAPK14_HUMAN CMGC 6e-85 291.1 1.0 301.0 301.0 167 168 169 171 173 53 71 75 147 149 148 150.0 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14

Ligand: GE5

Total number of chains: 3
Active chains: 2
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 66.7% 6HMRA
DFGinter None 1 33.3% 6HWUA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CK1 CSNK1D KC1D_HUMAN 6HMRA P48730 7 294 415.0 GE5:60301 Type1 Active DFGin 5.9016 14.8263 BLAminus -129.77, 165.39 78.39, 101.15 -107.5, 20.0 293.32, 102.36 -64.81, -25.32 in-in in 8.2845 Saltbr-in 2.7492 HRD-in -83.07, -49.96 76.13, 7.49 in-in-in SNCiii in-in ActLoopNT-in 2.8245 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -105.61, 123.18 APE9-dihe-na 112.73, -152.95 APE8-dihe-in -99.78, 125.38 APE8-rot-in 305.84 APE67-dihe-in -55.81, -38.54 -61.27, -36.97 APE12-dist-in 12.6253 APE11-dist-in 12.3101 APE10-dist-in 6.7702 APE9-dist-in 3.9726 None None None XRAY 1.782 0.176 0.199 A 314.0 287.0 1 35 35 0 [[9, 275]] 1.0 6hmr Homo sapiens CK1_CSNK1D_HUMAN CK1 1.9e-122 413.6 1.0 262.0 262.0 148 149 150 152 154 38 52 56 125 127 126 128.0 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
CK1 CSNK1D KC1D_HUMAN 6HMRB P48730 1 293 415.0 GE5:60301 Type1 Active DFGin 5.728 14.8214 BLAminus -132.18, 166.65 79.25, 99.25 -107.58, 20.5 292.42, 101.79 -65.16, -22.71 in-in in 8.1726 Saltbr-in 2.6324 HRD-in -83.94, -50.09 75.09, 8.55 in-in-in SNCiii in-in ActLoopNT-in 2.8028 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -95.7, -50.27 APE9-dihe-na -84.81, -142.78 APE8-dihe-in -93.52, 127.66 APE8-rot-in 306.5 APE67-dihe-in -55.61, -39.37 -59.1, -37.12 APE12-dist-in 12.085 APE11-dist-in 11.8293 APE10-dist-in 6.0284 APE9-dist-in 3.9267 None None None XRAY 1.782 0.176 0.199 B 314.0 279.0 14 35 35 0 [[9, 275]] 1.0 6hmr Homo sapiens CK1_CSNK1D_HUMAN CK1 1.9e-122 413.6 1.0 262.0 262.0 148 149 150 152 154 38 52 56 125 127 126 128.0 195 183 178 177 176 175 174 173 172 83 Casein kinase I isoform delta
CMGC MAPK14 MK14_HUMAN 6HWUA Q16539 5 353 360.0 GE5:404 Type1 Inactive DFGinter 9.5901 8.9682 None -118.08, 168.42 -117.72, 42.58 -170.41, 161.53 57.41, 87.05 -97.74, 161.01 in-in in 9.4576 Saltbr-in 2.9264 HRD-in -69.49, -51.73 75.06, -4.67 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_nnoo APE10-dihe-na 999.0, 73.5 APE9-dihe-na -65.73, 137.2 APE8-dihe-out -60.1, -34.07 APE8-rot-in 274.51 APE67-dihe-in -66.54, -24.29 -62.93, -25.28 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 11.2073 APE9-dist-out 11.5529 None None None XRAY 2.3 0.193 0.247 A 362.0 333.0 16 25 14 11 [[24, 308]] 1.0 6hwu Homo sapiens CMGC_MAPK14_HUMAN CMGC 6e-85 291.1 1.0 301.0 301.0 167 168 169 171 173 53 71 75 147 149 148 150.0 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14

Ligand: GE5

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name