Ligand: G98

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 3E8DA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AGC AKT2 AKT2_HUMAN 3E8DA P31751 146 480 481.0 G98:1 Type1.5_Back Active DFGin 6.6266 13.6021 BLAminus -131.95, 161.19 63.93, 96.17 -108.94, 28.77 296.25, 77.68 -84.56, 5.75 in-in in 9.2004 Saltbr-in 2.8047 HRD-in -77.32, -43.78 69.76, 5.0 in-in-in SNCiii in-in ActLoopNT-in 3.087 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -148.79, 164.59 APE9-dihe-na 136.0, -148.3 APE8-dihe-in -124.36, 129.64 APE8-rot-in 293.72 APE67-dihe-in -64.33, -19.25 -43.26, -53.33 APE12-dist-in 8.0866 APE11-dist-in 11.6652 APE10-dist-in 5.9945 APE9-dist-in 3.6895 S474D TPO309,TPO451 TPO309,TPO451 XRAY 2.7 0.214 0.268 A 335.0 316.0 0 28 28 0 [[152, 409]] 1.0 3e8d AGC_AKT2_HUMAN AGC 1.7e-99 338.1 1.0 260.0 260.0 292 293 294 296 298 181 200 204 272 274 273 275.0 332 320 315 314 313 312 311 310 309 230 RAC-beta serine/threonine-protein kinase
AGC AKT2 AKT2_HUMAN 3E8DB P31751 146 480 481.0 G98:1 Type1.5_Back Active DFGin 6.5882 13.5569 BLAminus -130.8, 161.71 64.68, 95.04 -108.93, 28.35 296.53, 82.54 -84.83, 6.03 in-in in 9.2388 Saltbr-in 2.8509 HRD-in -77.39, -43.59 70.5, 3.48 in-in-in SNCiii in-in ActLoopNT-in 3.0793 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -148.5, 165.61 APE9-dihe-na 135.83, -147.81 APE8-dihe-in -124.63, 129.91 APE8-rot-in 295.04 APE67-dihe-in -64.9, -18.78 -43.89, -52.5 APE12-dist-in 8.0825 APE11-dist-in 11.6493 APE10-dist-in 5.988 APE9-dist-in 3.7067 S474D TPO309,TPO451 TPO309,TPO451 XRAY 2.7 0.214 0.268 B 335.0 318.0 0 28 28 0 [[152, 409]] 1.0 3e8d AGC_AKT2_HUMAN AGC 1.7e-99 338.1 1.0 260.0 260.0 292 293 294 296 298 181 200 204 272 274 273 275.0 332 320 315 314 313 312 311 310 309 230 RAC-beta serine/threonine-protein kinase

Ligand: G98

Total number of chains: 8
Active chains: 8
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 8 100.0% 3E8EA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AGC PRKACA KAPCA_BOVIN 3E8EA P00517 8 351 351.0 G98:60351 Type1.5_Back Active DFGin 6.3073 14.6275 BLAminus -127.58, 177.12 59.26, 81.09 -89.3, 24.2 272.49, 51.41 -54.01, -38.82 in-in in 8.6228 Saltbr-in 2.6167 HRD-in -86.71, -49.98 69.16, 6.49 in-in-in SNCiii in-in ActLoopNT-in 2.8632 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -151.99, 154.32 APE9-dihe-na 133.62, -170.54 APE8-dihe-in -106.52, 129.54 APE8-rot-in 301.27 APE67-dihe-in -53.09, -32.91 -42.99, -51.98 APE12-dist-in 8.2069 APE11-dist-in 11.4816 APE10-dist-in 5.9204 APE9-dist-in 3.7722 None SEP11,TPO198,SEP339 SEP11,TPO198,SEP339 XRAY 2.0 0.245 0.279 A 350.0 344.0 0 25 25 0 [[44, 298]] 1.0 3e8e Bos taurus AGC_PRKACA_BOVIN AGC 1.3e-94 322.2 1.0 260.0 260.0 184 185 186 188 190 73 92 96 164 166 165 167.0 221 209 204 203 202 201 200 199 198 122 cAMP-dependent protein kinase catalytic subunit alpha
AGC PRKACA KAPCA_BOVIN 3E8EB P00517 13 351 351.0 G98:60351 Type1.5_Back Active DFGin 6.2938 14.7178 BLAminus -125.84, -172.92 50.21, 81.31 -89.14, 23.18 270.21, 58.55 -50.98, -43.5 in-in in 8.6642 Saltbr-in 2.6654 HRD-in -82.38, -53.17 68.54, 5.22 in-in-in SNCiii in-in ActLoopNT-in 2.8797 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -152.38, 161.75 APE9-dihe-na 128.75, -165.32 APE8-dihe-in -112.15, 133.4 APE8-rot-in 300.5 APE67-dihe-in -58.46, -24.04 -42.84, -57.3 APE12-dist-in 8.0985 APE11-dist-in 11.3489 APE10-dist-in 5.8215 APE9-dist-in 3.724 None SEP11,TPO198,SEP339 SEP11,TPO198,SEP339 XRAY 2.0 0.245 0.279 B 350.0 339.0 0 25 25 0 [[44, 298]] 1.0 3e8e Bos taurus AGC_PRKACA_BOVIN AGC 1.3e-94 322.2 1.0 260.0 260.0 184 185 186 188 190 73 92 96 164 166 165 167.0 221 209 204 203 202 201 200 199 198 122 cAMP-dependent protein kinase catalytic subunit alpha
AGC PRKACA KAPCA_BOVIN 3E8EE P00517 8 351 351.0 G98:60351 Type1.5_Back Active DFGin 6.5022 14.7143 BLAminus -125.94, 177.63 60.28, 78.38 -89.05, 26.68 272.68, 53.04 -58.15, -33.43 in-in in 8.5959 Saltbr-in 2.7412 HRD-in -83.69, -53.19 69.3, 12.83 in-in-in SNCiii in-in ActLoopNT-in 2.9203 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -154.44, 161.83 APE9-dihe-na 125.18, -160.92 APE8-dihe-in -119.48, 128.06 APE8-rot-in 308.71 APE67-dihe-in -61.97, -23.41 -42.69, -51.33 APE12-dist-in 8.1077 APE11-dist-in 11.5081 APE10-dist-in 5.9999 APE9-dist-in 3.6674 None SEP11,TPO198,SEP339 SEP11,TPO198,SEP339 XRAY 2.0 0.245 0.279 E 350.0 344.0 0 25 25 0 [[44, 298]] 1.0 3e8e Bos taurus AGC_PRKACA_BOVIN AGC 1.3e-94 322.2 1.0 260.0 260.0 184 185 186 188 190 73 92 96 164 166 165 167.0 221 209 204 203 202 201 200 199 198 122 cAMP-dependent protein kinase catalytic subunit alpha
AGC PRKACA KAPCA_BOVIN 3E8EI P00517 4 351 351.0 G98:60351 Type1.5_Back Active DFGin 6.2839 14.6216 BLAminus -121.51, -176.84 52.35, 81.35 -90.04, 28.89 273.59, 58.29 -59.59, -35.26 in-in in 8.5151 Saltbr-in 2.667 HRD-in -96.55, -53.06 68.92, 16.49 in-in-in SNCiii in-in ActLoopNT-in 2.8724 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -152.85, 164.56 APE9-dihe-na 117.18, -165.89 APE8-dihe-in -113.08, 128.95 APE8-rot-in 295.01 APE67-dihe-in -62.64, -25.23 -41.3, -50.45 APE12-dist-in 8.1826 APE11-dist-in 11.4443 APE10-dist-in 5.9011 APE9-dist-in 3.5317 None SEP11,TPO198,SEP339 SEP11,TPO198,SEP339 XRAY 2.0 0.245 0.279 I 350.0 348.0 0 25 25 0 [[44, 298]] 1.0 3e8e Bos taurus AGC_PRKACA_BOVIN AGC 1.3e-94 322.2 1.0 260.0 260.0 184 185 186 188 190 73 92 96 164 166 165 167.0 221 209 204 203 202 201 200 199 198 122 cAMP-dependent protein kinase catalytic subunit alpha
AGC PRKACA KAPCA_BOVIN 3E8EL P00517 14 351 351.0 G98:60351 Type1.5_Back Active DFGin 6.3558 14.4455 BLAminus -126.34, 179.53 56.51, 87.88 -97.22, 26.99 274.78, 53.86 -54.08, -36.01 in-in in 8.4902 Saltbr-in 2.9058 HRD-in -84.79, -53.72 69.04, 14.43 in-in-in SNCiii in-in ActLoopNT-in 2.9175 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -147.8, 165.17 APE9-dihe-na 117.16, -168.03 APE8-dihe-in -109.85, 132.76 APE8-rot-in 309.54 APE67-dihe-in -58.05, -25.67 -43.08, -54.13 APE12-dist-in 8.0742 APE11-dist-in 11.4769 APE10-dist-in 5.8902 APE9-dist-in 3.5416 None SEP11,TPO198,SEP339 SEP11,TPO198,SEP339 XRAY 2.0 0.245 0.279 L 350.0 338.0 0 25 25 0 [[44, 298]] 1.0 3e8e Bos taurus AGC_PRKACA_BOVIN AGC 1.3e-94 322.2 1.0 260.0 260.0 184 185 186 188 190 73 92 96 164 166 165 167.0 221 209 204 203 202 201 200 199 198 122 cAMP-dependent protein kinase catalytic subunit alpha
AGC PRKACA KAPCA_BOVIN 3E8EP P00517 8 351 351.0 G98:60351 Type1.5_Back Active DFGin 6.3511 14.4567 BLAminus -129.89, 174.6 59.69, 84.32 -91.75, 22.85 273.06, 63.33 -54.83, -37.28 in-in in 8.5071 Saltbr-in 3.0872 HRD-in -91.09, -52.59 71.75, 13.86 in-in-in SNCiii in-in ActLoopNT-in 2.8806 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -157.01, 169.23 APE9-dihe-na 113.75, -166.64 APE8-dihe-in -114.16, 128.38 APE8-rot-in 299.83 APE67-dihe-in -58.07, -28.95 -41.88, -52.2 APE12-dist-in 8.1136 APE11-dist-in 11.4255 APE10-dist-in 5.9681 APE9-dist-in 3.5443 None SEP11,TPO198,SEP339 SEP11,TPO198,SEP339 XRAY 2.0 0.245 0.279 P 350.0 344.0 0 25 25 0 [[44, 298]] 1.0 3e8e Bos taurus AGC_PRKACA_BOVIN AGC 1.3e-94 322.2 1.0 260.0 260.0 184 185 186 188 190 73 92 96 164 166 165 167.0 221 209 204 203 202 201 200 199 198 122 cAMP-dependent protein kinase catalytic subunit alpha
AGC AKT2 AKT2_HUMAN 3E8DA P31751 146 480 481.0 G98:1 Type1.5_Back Active DFGin 6.6266 13.6021 BLAminus -131.95, 161.19 63.93, 96.17 -108.94, 28.77 296.25, 77.68 -84.56, 5.75 in-in in 9.2004 Saltbr-in 2.8047 HRD-in -77.32, -43.78 69.76, 5.0 in-in-in SNCiii in-in ActLoopNT-in 3.087 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -148.79, 164.59 APE9-dihe-na 136.0, -148.3 APE8-dihe-in -124.36, 129.64 APE8-rot-in 293.72 APE67-dihe-in -64.33, -19.25 -43.26, -53.33 APE12-dist-in 8.0866 APE11-dist-in 11.6652 APE10-dist-in 5.9945 APE9-dist-in 3.6895 S474D TPO309,TPO451 TPO309,TPO451 XRAY 2.7 0.214 0.268 A 335.0 316.0 0 28 28 0 [[152, 409]] 1.0 3e8d Homo sapiens AGC_AKT2_HUMAN AGC 1.7e-99 338.1 1.0 260.0 260.0 292 293 294 296 298 181 200 204 272 274 273 275.0 332 320 315 314 313 312 311 310 309 230 RAC-beta serine/threonine-protein kinase
AGC AKT2 AKT2_HUMAN 3E8DB P31751 146 480 481.0 G98:1 Type1.5_Back Active DFGin 6.5882 13.5569 BLAminus -130.8, 161.71 64.68, 95.04 -108.93, 28.35 296.53, 82.54 -84.83, 6.03 in-in in 9.2388 Saltbr-in 2.8509 HRD-in -77.39, -43.59 70.5, 3.48 in-in-in SNCiii in-in ActLoopNT-in 3.0793 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -148.5, 165.61 APE9-dihe-na 135.83, -147.81 APE8-dihe-in -124.63, 129.91 APE8-rot-in 295.04 APE67-dihe-in -64.9, -18.78 -43.89, -52.5 APE12-dist-in 8.0825 APE11-dist-in 11.6493 APE10-dist-in 5.988 APE9-dist-in 3.7067 S474D TPO309,TPO451 TPO309,TPO451 XRAY 2.7 0.214 0.268 B 335.0 318.0 0 28 28 0 [[152, 409]] 1.0 3e8d Homo sapiens AGC_AKT2_HUMAN AGC 1.7e-99 338.1 1.0 260.0 260.0 292 293 294 296 298 181 200 204 272 274 273 275.0 332 320 315 314 313 312 311 310 309 230 RAC-beta serine/threonine-protein kinase

Ligand: G98

Total number of chains: 6
Active chains: 6
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 6 100.0% 3E8EA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AGC PRKACA KAPCA_BOVIN 3E8EA P00517 8 351 351.0 G98:60351 Type1.5_Back Active DFGin 6.3073 14.6275 BLAminus -127.58, 177.12 59.26, 81.09 -89.3, 24.2 272.49, 51.41 -54.01, -38.82 in-in in 8.6228 Saltbr-in 2.6167 HRD-in -86.71, -49.98 69.16, 6.49 in-in-in SNCiii in-in ActLoopNT-in 2.8632 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -151.99, 154.32 APE9-dihe-na 133.62, -170.54 APE8-dihe-in -106.52, 129.54 APE8-rot-in 301.27 APE67-dihe-in -53.09, -32.91 -42.99, -51.98 APE12-dist-in 8.2069 APE11-dist-in 11.4816 APE10-dist-in 5.9204 APE9-dist-in 3.7722 None SEP11,TPO198,SEP339 SEP11,TPO198,SEP339 XRAY 2.0 0.245 0.279 A 350.0 344.0 0 25 25 0 [[44, 298]] 1.0 3e8e Bos taurus AGC_PRKACA_BOVIN AGC 1.3e-94 322.2 1.0 260.0 260.0 184 185 186 188 190 73 92 96 164 166 165 167.0 221 209 204 203 202 201 200 199 198 122 cAMP-dependent protein kinase catalytic subunit alpha
AGC PRKACA KAPCA_BOVIN 3E8EB P00517 13 351 351.0 G98:60351 Type1.5_Back Active DFGin 6.2938 14.7178 BLAminus -125.84, -172.92 50.21, 81.31 -89.14, 23.18 270.21, 58.55 -50.98, -43.5 in-in in 8.6642 Saltbr-in 2.6654 HRD-in -82.38, -53.17 68.54, 5.22 in-in-in SNCiii in-in ActLoopNT-in 2.8797 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -152.38, 161.75 APE9-dihe-na 128.75, -165.32 APE8-dihe-in -112.15, 133.4 APE8-rot-in 300.5 APE67-dihe-in -58.46, -24.04 -42.84, -57.3 APE12-dist-in 8.0985 APE11-dist-in 11.3489 APE10-dist-in 5.8215 APE9-dist-in 3.724 None SEP11,TPO198,SEP339 SEP11,TPO198,SEP339 XRAY 2.0 0.245 0.279 B 350.0 339.0 0 25 25 0 [[44, 298]] 1.0 3e8e Bos taurus AGC_PRKACA_BOVIN AGC 1.3e-94 322.2 1.0 260.0 260.0 184 185 186 188 190 73 92 96 164 166 165 167.0 221 209 204 203 202 201 200 199 198 122 cAMP-dependent protein kinase catalytic subunit alpha
AGC PRKACA KAPCA_BOVIN 3E8EE P00517 8 351 351.0 G98:60351 Type1.5_Back Active DFGin 6.5022 14.7143 BLAminus -125.94, 177.63 60.28, 78.38 -89.05, 26.68 272.68, 53.04 -58.15, -33.43 in-in in 8.5959 Saltbr-in 2.7412 HRD-in -83.69, -53.19 69.3, 12.83 in-in-in SNCiii in-in ActLoopNT-in 2.9203 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -154.44, 161.83 APE9-dihe-na 125.18, -160.92 APE8-dihe-in -119.48, 128.06 APE8-rot-in 308.71 APE67-dihe-in -61.97, -23.41 -42.69, -51.33 APE12-dist-in 8.1077 APE11-dist-in 11.5081 APE10-dist-in 5.9999 APE9-dist-in 3.6674 None SEP11,TPO198,SEP339 SEP11,TPO198,SEP339 XRAY 2.0 0.245 0.279 E 350.0 344.0 0 25 25 0 [[44, 298]] 1.0 3e8e Bos taurus AGC_PRKACA_BOVIN AGC 1.3e-94 322.2 1.0 260.0 260.0 184 185 186 188 190 73 92 96 164 166 165 167.0 221 209 204 203 202 201 200 199 198 122 cAMP-dependent protein kinase catalytic subunit alpha
AGC PRKACA KAPCA_BOVIN 3E8EI P00517 4 351 351.0 G98:60351 Type1.5_Back Active DFGin 6.2839 14.6216 BLAminus -121.51, -176.84 52.35, 81.35 -90.04, 28.89 273.59, 58.29 -59.59, -35.26 in-in in 8.5151 Saltbr-in 2.667 HRD-in -96.55, -53.06 68.92, 16.49 in-in-in SNCiii in-in ActLoopNT-in 2.8724 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -152.85, 164.56 APE9-dihe-na 117.18, -165.89 APE8-dihe-in -113.08, 128.95 APE8-rot-in 295.01 APE67-dihe-in -62.64, -25.23 -41.3, -50.45 APE12-dist-in 8.1826 APE11-dist-in 11.4443 APE10-dist-in 5.9011 APE9-dist-in 3.5317 None SEP11,TPO198,SEP339 SEP11,TPO198,SEP339 XRAY 2.0 0.245 0.279 I 350.0 348.0 0 25 25 0 [[44, 298]] 1.0 3e8e Bos taurus AGC_PRKACA_BOVIN AGC 1.3e-94 322.2 1.0 260.0 260.0 184 185 186 188 190 73 92 96 164 166 165 167.0 221 209 204 203 202 201 200 199 198 122 cAMP-dependent protein kinase catalytic subunit alpha
AGC PRKACA KAPCA_BOVIN 3E8EL P00517 14 351 351.0 G98:60351 Type1.5_Back Active DFGin 6.3558 14.4455 BLAminus -126.34, 179.53 56.51, 87.88 -97.22, 26.99 274.78, 53.86 -54.08, -36.01 in-in in 8.4902 Saltbr-in 2.9058 HRD-in -84.79, -53.72 69.04, 14.43 in-in-in SNCiii in-in ActLoopNT-in 2.9175 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -147.8, 165.17 APE9-dihe-na 117.16, -168.03 APE8-dihe-in -109.85, 132.76 APE8-rot-in 309.54 APE67-dihe-in -58.05, -25.67 -43.08, -54.13 APE12-dist-in 8.0742 APE11-dist-in 11.4769 APE10-dist-in 5.8902 APE9-dist-in 3.5416 None SEP11,TPO198,SEP339 SEP11,TPO198,SEP339 XRAY 2.0 0.245 0.279 L 350.0 338.0 0 25 25 0 [[44, 298]] 1.0 3e8e Bos taurus AGC_PRKACA_BOVIN AGC 1.3e-94 322.2 1.0 260.0 260.0 184 185 186 188 190 73 92 96 164 166 165 167.0 221 209 204 203 202 201 200 199 198 122 cAMP-dependent protein kinase catalytic subunit alpha
AGC PRKACA KAPCA_BOVIN 3E8EP P00517 8 351 351.0 G98:60351 Type1.5_Back Active DFGin 6.3511 14.4567 BLAminus -129.89, 174.6 59.69, 84.32 -91.75, 22.85 273.06, 63.33 -54.83, -37.28 in-in in 8.5071 Saltbr-in 3.0872 HRD-in -91.09, -52.59 71.75, 13.86 in-in-in SNCiii in-in ActLoopNT-in 2.8806 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -157.01, 169.23 APE9-dihe-na 113.75, -166.64 APE8-dihe-in -114.16, 128.38 APE8-rot-in 299.83 APE67-dihe-in -58.07, -28.95 -41.88, -52.2 APE12-dist-in 8.1136 APE11-dist-in 11.4255 APE10-dist-in 5.9681 APE9-dist-in 3.5443 None SEP11,TPO198,SEP339 SEP11,TPO198,SEP339 XRAY 2.0 0.245 0.279 P 350.0 344.0 0 25 25 0 [[44, 298]] 1.0 3e8e Bos taurus AGC_PRKACA_BOVIN AGC 1.3e-94 322.2 1.0 260.0 260.0 184 185 186 188 190 73 92 96 164 166 165 167.0 221 209 204 203 202 201 200 199 198 122 cAMP-dependent protein kinase catalytic subunit alpha