Ligand: FGF (Roblitinib)

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 3 100.0% 6JPJA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR FGFR4 FGFR4_HUMAN 6JPJA 2.638 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao FGF Type1 454 - 752 0 None C477A,R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 6YI8A 2.13 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_niiai APEdist_aaao FGF Type1 453 - 753 0 None None Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 6YI8B 2.13 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_nniai APEdist_aaao FGF Type1 451 - 752 0 None None Fibroblast growth factor receptor 4

Ligand: FGF (Roblitinib)

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 3 100.0% 6JPJA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR FGFR4 FGFR4_HUMAN 6JPJA 2.638 Inactive DFGin‑BLAplus in-in out-out TYR APEdihe_iioai APEdist_aaao FGF Type1 454 - 752 0 None C477A,R664E Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 6YI8A 2.13 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_niiai APEdist_aaao FGF Type1 453 - 753 0 None None Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 6YI8B 2.13 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_nniai APEdist_aaao FGF Type1 451 - 752 0 None None Fibroblast growth factor receptor 4 Homo sapiens

Ligand: FGF (Roblitinib)

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism